Potential role of signal transducer and activator of transcription (STAT) 3 signaling pathway in inflammation, survival, proliferation and invasion of hepatocellular carcinoma A Subramaniam, MK Shanmugam, E Perumal, F Li, A Nachiyappan, X Dai, ... Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1835 (1), 46-60, 2013 | 351 | 2013 |
Celastrol inhibits tumor cell proliferation and promotes apoptosis through the activation of c-Jun N-terminal kinase and suppression of PI3 K/Akt signaling pathways R Kannaiyan, KA Manu, L Chen, F Li, P Rajendran, A Subramaniam, ... Apoptosis 16, 1028-1041, 2011 | 179 | 2011 |
Emodin inhibits growth and induces apoptosis in an orthotopic hepatocellular carcinoma model by blocking activation of STAT3 A Subramaniam, MK Shanmugam, TH Ong, F Li, E Perumal, L Chen, ... British journal of pharmacology 170 (4), 807-821, 2013 | 152 | 2013 |
Emodin suppresses migration and invasion through the modulation of CXCR4 expression in an orthotopic model of human hepatocellular carcinoma KA Manu, MK Shanmugam, TH Ong, A Subramaniam, KS Siveen, ... PloS one 8 (3), e57015, 2013 | 71 | 2013 |
Therapeutic efficacy of Tamarindus indica (L) to protect against fluoride-induced oxidative stress in the liver of female rats P Ekambaram, T Namitha, S Bhuvaneswari, S Aruljothi, D Vasanth, ... Fluoride 43 (2), 134, 2010 | 54 | 2010 |
An anthraquinone derivative, emodin sensitizes hepatocellular carcinoma cells to TRAIL induced apoptosis through the induction of death receptors and downregulation of cell … A Subramaniam, SY Loo, P Rajendran, KA Manu, E Perumal, F Li, ... Apoptosis 18, 1175-1187, 2013 | 48 | 2013 |
Design, synthesis, and structural characterization of lysine covalent BH3 peptides targeting Mcl-1 L Gambini, P Udompholkul, C Baggio, A Muralidharan, N Kenjić, Z Assar, ... Journal of medicinal chemistry 64 (8), 4903-4912, 2021 | 24 | 2021 |
Role of prolyl hydroxylase domain proteins in bone metabolism D Wolf, A Muralidharan, S Mohan Osteoporosis and Sarcopenia 8 (1), 1-10, 2022 | 6 | 2022 |
Possible involvement of signal transducer and activator of transcription-3 (STAT3) signaling pathway in the initiation and progression of hepatocellular carcinoma A Subramaniam, MK Shanmugam, E Perumal, F Li, A Nachiyappan, ... Perspectives in Cancer Prevention-Translational Cancer Research, 73-87, 2014 | 3 | 2014 |
Metformin treatment outcomes in relation to obesity and cation transporter expression in mouse models of endometrial cancer A Muralidharan, H Guo, J Han, L Zhang, W Sun, Y Yin, C Zhou, ... Cancer Research 79 (13_Supplement), 3609-3609, 2019 | 1 | 2019 |
Sex-Specific Effects of THRβ Signaling on Metabolic Responses to High Fat Diet in Mice A Muralidharan, GA Gomez, C Kesavan, S Pourteymoor, D Larkin, ... Endocrinology 165 (8), bqae075, 2024 | | 2024 |
OCT and MATE transporters mediate uptake and antiproliferative activity of the anticancer drug metformin in endometrial cancer cell lines A Muralidharan, VL Bae-Jump, DR Thakker Cancer Research 78 (13_Supplement), 4916-4916, 2018 | | 2018 |
Aruljothi Subramaniam, Muthu K. Shanmugam, Ekambaram Perumal, Feng Li, Alamelu Nachiyappan AP Kumar, BKH Tan, G Sethi Perspectives in Cancer Prevention-Translational Cancer Research, 73, 2013 | | 2013 |
Elucidation of Molecular Mechanisms Involved in the Anticancer Effect of Emodin (1, 3, 8 trihydroxy-6-methylanthraquinone): Mediated through the Induction of Apoptosis … S ARULJOTHI, P EKAMBARAM | | 2013 |
An anthraquinone derivative, emodin sensitizes hepatocellular carcinoma cells to TRAIL induced apoptosis through the induction of death receptors signaling MK Shanmugam, A Subramaniam, SY Loo, R Peramaiyan, ... JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY 27, 330-330, 2012 | | 2012 |
Modulation of Signal Transducer and Activator of Transcription 3 by emodin through the induction of a phosphatase leads to the suppression of HCC growth in orthotopic mouse model MK Shanmugam, TH Ong, R Peramaiyan, A Subramaniam, KM Hui, ... Cancer Research 72 (8_Supplement), 2813-2813, 2012 | | 2012 |