Ductal pancreatic cancer modeling and drug screening using human pluripotent stem cell–and patient-derived tumor organoids L Huang, A Holtzinger, I Jagan, M BeGora, I Lohse, N Ngai, C Nostro, ... Nature medicine 21 (11), 1364-1371, 2015 | 767 | 2015 |
A renewed model of pancreatic cancer evolution based on genomic rearrangement patterns F Notta, M Chan-Seng-Yue, M Lemire, Y Li, GW Wilson, AA Connor, ... Nature 538 (7625), 378-382, 2016 | 582 | 2016 |
Genomics-driven precision medicine for advanced pancreatic cancer: early results from the COMPASS trial KL Aung, SE Fischer, RE Denroche, GH Jang, A Dodd, S Creighton, ... Clinical Cancer Research 24 (6), 1344-1354, 2018 | 552 | 2018 |
Transcription phenotypes of pancreatic cancer are driven by genomic events during tumor evolution M Chan-Seng-Yue, JC Kim, GW Wilson, K Ng, EF Figueroa, GM O’Kane, ... Nature genetics 52 (2), 231-240, 2020 | 518 | 2020 |
Prevalence of germline mutations in cancer predisposition genes in patients with pancreatic cancer RC Grant, I Selander, AA Connor, S Selvarajah, A Borgida, L Briollais, ... Gastroenterology 148 (3), 556-564, 2015 | 344 | 2015 |
Association of distinct mutational signatures with correlates of increased immune activity in pancreatic ductal adenocarcinoma AA Connor, RE Denroche, GH Jang, L Timms, SN Kalimuthu, I Selander, ... JAMA oncology 3 (6), 774-783, 2017 | 267 | 2017 |
Mammary analog secretory carcinoma of salivary gland origin with the ETV6 gene rearrangement by FISH: expanded morphologic and immunohistochemical spectrum of a recently … A Connor, B Perez-Ordoñez, M Shago, A Skálová, I Weinreb The American journal of surgical pathology 36 (1), 27-34, 2012 | 261 | 2012 |
Pancreatic cancer evolution and heterogeneity: integrating omics and clinical data AA Connor, S Gallinger Nature Reviews Cancer 22 (3), 131-142, 2022 | 212 | 2022 |
Integration of genomic and transcriptional features in pancreatic cancer reveals increased cell cycle progression in metastases AA Connor, RE Denroche, GH Jang, M Lemire, A Zhang, ... Cancer cell 35 (2), 267-282. e7, 2019 | 193 | 2019 |
A four-chemokine signature is associated with a T-cell–inflamed phenotype in primary and metastatic pancreatic cancer JM Romero, B Grünwald, GH Jang, PP Bavi, A Jhaveri, M Masoomian, ... Clinical Cancer Research 26 (8), 1997-2010, 2020 | 123 | 2020 |
Molecular events in the natural history of pancreatic cancer LE Oldfield, AA Connor, S Gallinger Trends in cancer 3 (5), 336-346, 2017 | 81 | 2017 |
Candidate DNA repair susceptibility genes identified by exome sequencing in high-risk pancreatic cancer AL Smith, N Alirezaie, A Connor, M Chan-Seng-Yue, R Grant, I Selander, ... Cancer letters 370 (2), 302-312, 2016 | 66 | 2016 |
Characterization, detection, and treatment approaches for homologous recombination deficiency in cancer GM O’Kane, AA Connor, S Gallinger Trends in Molecular Medicine 23 (12), 1121-1137, 2017 | 62 | 2017 |
Exome-wide association study of pancreatic cancer risk RC Grant, RE Denroche, A Borgida, C Virtanen, N Cook, AL Smith, ... Gastroenterology 154 (3), 719-722. e3, 2018 | 49 | 2018 |
A clinical‐radiomic model for improved prognostication of surgical candidates with colorectal liver metastases J Shur, M Orton, A Connor, S Fischer, CA Moulton, S Gallinger, DM Koh, ... Journal of Surgical Oncology 121 (2), 357-364, 2020 | 39 | 2020 |
Hereditary pancreatic cancer syndromes AA Connor, S Gallinger Surgical Oncology Clinics 24 (4), 733-764, 2015 | 37 | 2015 |
Central, but not peripheral, circulating tumor cells are prognostic in patients undergoing resection of colorectal cancer liver metastases AA Connor, K McNamara, E Al-Sukhni, J Diskin, D Chan, C Ash, ... Annals of Surgical Oncology 23, 2168-2175, 2016 | 34 | 2016 |
Increased in vitro and in vivo sensitivity of BRCA2-associated pancreatic cancer to the poly (ADP-ribose) polymerase-1/2 inhibitor BMN 673 AZ Andrei, A Hall, AL Smith, C Bascuñana, A Malina, A Connor, ... Cancer letters 364 (1), 8-16, 2015 | 34 | 2015 |
Reflex Testing for Germline BRCA1, BRCA2, PALB2, and ATM Mutations in Pancreatic Cancer: Mutation Prevalence and Clinical Outcomes From Two Canadian … AL Smith, C Wong, A Cuggia, A Borgida, S Holter, A Hall, AA Connor, ... JCO Precision Oncology 2, 1-16, 2018 | 33 | 2018 |
Mutations in mitochondrial DNA from pancreatic ductal adenocarcinomas associate with survival times of patients and accumulate as tumors progress JF Hopkins, RE Denroche, JA Aguiar, F Notta, AA Connor, JM Wilson, ... Gastroenterology 154 (6), 1620-1624. e5, 2018 | 28 | 2018 |