Effect of the CYP2D6 genotype on metoprolol metabolism persists during long-term treatment T Rau, R Heide, K Bergmann, H Wuttke, U Werner, N Feifel, ... Pharmacogenetics and Genomics 12 (6), 465-472, 2002 | 208 | 2002 |
Simultaneous determination of aceclofenac and three of its metabolites in human plasma by high‐performance liquid chromatography B Hinz, D Auge, T Rau, S Rietbrock, K Brune, U Werner Biomedical Chromatography 17 (4), 268-275, 2003 | 154 | 2003 |
Impact of the CYP2D6 genotype on the clinical effects of metoprolol: a prospective longitudinal study T Rau, H Wuttke, LM Michels, U Werner, K Bergmann, M Kreft, MF Fromm, ... Clinical Pharmacology & Therapeutics 85 (3), 269-272, 2009 | 149 | 2009 |
Caffeine accelerates absorption and enhances the analgesic effect of acetaminophen B Renner, G Clarke, T Grattan, A Beisel, C Mueller, U Werner, G Kobal, ... The Journal of Clinical Pharmacology 47 (6), 715-726, 2007 | 131 | 2007 |
Aceclofenac spares cyclooxygenase 1 as a result of limited but sustained biotransformation to diclofenac B Hinz, T Rau, D Auge, U Werner, R Ramer, S Rietbrock, K Brune Clinical Pharmacology & Therapeutics 74 (3), 222-235, 2003 | 121 | 2003 |
Characterization of β‐adrenoceptor antagonists as substrates and inhibitors of the drug transporter P‐glycoprotein1 I Bachmakov, U Werner, B Endress, D Auge, MF Fromm Fundamental & clinical pharmacology 20 (3), 273-282, 2006 | 120 | 2006 |
Celecoxib inhibits metabolism of cytochrome P450 2D6 substrate metoprolol in humans U Werner, D Werner, T Rau, MF Fromm, B Hinz, K Brune Clinical Pharmacology & Therapeutics 74 (2), 130-137, 2003 | 120 | 2003 |
Survey of adverse drug reactions on a pediatric ward: a strategy for early and detailed detection J Weiss, S Krebs, C Hoffmann, U Werner, A Neubert, K Brune, W Rascher Pediatrics 110 (2), 254-257, 2002 | 120 | 2002 |
Expression and function of β-glucuronidase in pancreatic cancer: potential role in drug targeting B Sperker, U Werner, TE Mürdter, C Tekkaya, P Fritz, R Wacke, U Adam, ... Naunyn-Schmiedeberg's Archives of Pharmacology 362, 110-115, 2000 | 107 | 2000 |
Bioavailability of diclofenac potassium at low doses B Hinz, J Chevts, B Renner, H Wuttke, T Rau, A Schmidt, I Szelenyi, ... British journal of clinical pharmacology 59 (1), 80-84, 2005 | 105 | 2005 |
Celecoxib modulates the expression of cyclooxygenase-2, ki67, apoptosis-related marker, and microvessel density in human cervical cancer: a pilot study G Ferrandina, FO Ranelletti, F Legge, L Lauriola, V Salutari, M Gessi, ... Clinical cancer research 9 (12), 4324-4331, 2003 | 102 | 2003 |
Gender is an important determinant of the disposition of the loop diuretic torasemide U Werner, D Werner, S Heinbüchner, B Graf, H Ince, S Kische, ... The Journal of Clinical Pharmacology 50 (2), 160-168, 2010 | 77 | 2010 |
Investigation of the pharmacokinetics of celecoxib by liquid chromatography–mass spectrometry U Werner, D Werner, A Pahl, R Mundkowski, M Gillich, K Brune Biomedical Chromatography 16 (1), 56-60, 2002 | 75 | 2002 |
Role of nitric oxide in zymosan induced paw inflammation and thermal hyperalgesia H Gühring, I Tegeder, J Lötsch, A Pahl, U Werner, PW Reeh, K Rehse, ... Inflammation Research 50, 83-88, 2001 | 65 | 2001 |
Determinants of steady-state torasemide pharmacokinetics: impact of pharmacogenetic factors, gender and angiotensin II receptor blockers D Werner, U Werner, A Meybaum, B Schmidt, S Umbreen, A Grosch, ... Clinical pharmacokinetics 47, 323-332, 2008 | 59 | 2008 |
Effect of amiodarone on the plasma levels of metoprolol D Werner, H Wuttke, MF Fromm, S Schaefer, T Eschenhagen, K Brune, ... The American journal of cardiology 94 (10), 1319-1321, 2004 | 57 | 2004 |
Single-dose nimodipine normalizes impaired retinal circulation in normal tension glaucoma F Michalk, G Michelson, J Harazny, U Werner, WG Daniel, D Werner Journal of Glaucoma 13 (2), 158-162, 2004 | 51 | 2004 |
The penetration of ciprofloxacin into human pancreatic and peripancreatic necroses in acute necrotizing pancreatitis U Adam, S Herms, U Werner, H Strubelt, F Makowiec, UT Hopt, ... Infection 29, 326-331, 2001 | 48 | 2001 |
A liquid chromatography–mass spectrometry method for the quantification of both etoricoxib and valdecoxib in human plasma U Werner, D Werner, B Hinz, C Lambrecht, K Brune Biomedical Chromatography 19 (2), 113-118, 2005 | 47 | 2005 |
Tolerability of β‐blockers metabolized via cytochrome P450 2D6 is sex‐dependent PA Thürmann, S Haack, U Werner, J Szymanski, G Haase, B Drewelow, ... Clinical Pharmacology & Therapeutics 80 (5), 551-553, 2006 | 42 | 2006 |