Ibrutinib is an irreversible molecular inhibitor of ITK driving a Th1-selective pressure in T lymphocytes JA Dubovsky, KA Beckwith, G Natarajan, JA Woyach, S Jaglowski, ... Blood, The Journal of the American Society of Hematology 122 (15), 2539-2549, 2013 | 826 | 2013 |
Selective inhibitors of nuclear export show that CRM1/XPO1 is a target in chronic lymphocytic leukemia R Lapalombella, Q Sun, K Williams, L Tangeman, S Jha, Y Zhong, ... Blood, The Journal of the American Society of Hematology 120 (23), 4621-4634, 2012 | 372 | 2012 |
Prolonged lymphocytosis during ibrutinib therapy is associated with distinct molecular characteristics and does not indicate a suboptimal response to therapy JA Woyach, K Smucker, LL Smith, A Lozanski, Y Zhong, AS Ruppert, ... Blood, The Journal of the American Society of Hematology 123 (12), 1810-1817, 2014 | 347 | 2014 |
Ibrutinib treatment ameliorates murine chronic graft-versus-host disease JA Dubovsky, R Flynn, J Du, BK Harrington, Y Zhong, B Kaffenberger, ... The Journal of clinical investigation 124 (11), 4867-4876, 2014 | 213 | 2014 |
Hypermorphic mutation of phospholipase C, γ2 acquired in ibrutinib-resistant CLL confers BTK independency upon B-cell receptor activation TM Liu, JA Woyach, Y Zhong, A Lozanski, G Lozanski, S Dong, E Strattan, ... Blood, The Journal of the American Society of Hematology 126 (1), 61-68, 2015 | 200 | 2015 |
Myeloid-derived suppressor cells express Bruton's tyrosine kinase and can be depleted in tumor-bearing hosts by ibrutinib treatment A Stiff, P Trikha, R Wesolowski, K Kendra, V Hsu, S Uppati, E McMichael, ... Cancer research 76 (8), 2125-2136, 2016 | 192 | 2016 |
Application of next generation sequencing in laboratory medicine Y Zhong, F Xu, J Wu, J Schubert, MM Li Annals of laboratory medicine 41 (1), 25-43, 2021 | 158 | 2021 |
IPI-145 antagonizes intrinsic and extrinsic survival signals in chronic lymphocytic leukemia cells S Dong, D Guinn, JA Dubovsky, Y Zhong, A Lehman, J Kutok, JA Woyach, ... Blood, The Journal of the American Society of Hematology 124 (24), 3583-3586, 2014 | 123 | 2014 |
Selinexor suppresses downstream effectors of B-cell activation, proliferation and migration in chronic lymphocytic leukemia cells Y Zhong, D El-Gamal, JA Dubovsky, KA Beckwith, BK Harrington, ... Leukemia, doi: 10.1038/leu.2014.9., 2014 | 71 | 2014 |
Targeting Interleukin-2-inducible T-cell Kinase (ITK) and Resting Lymphocyte Kinase (RLK) Using a Novel Covalent Inhibitor PRN694. Y Zhong, D S, S E, R L, B JP, T K, M A, P P, B JM, B A, O TD, V E, B KA, ... J Biol Chem, 2015 | 57 | 2015 |
PKC-β as a therapeutic target in CLL: PKC inhibitor AEB071 demonstrates preclinical activity in CLL D El-Gamal, K Williams, TD LaFollette, M Cannon, JS Blachly, Y Zhong, ... Blood, The Journal of the American Society of Hematology 124 (9), 1481-1491, 2014 | 57 | 2014 |
The B-cell receptor pathway: a critical component of healthy and malignant immune biology Y Zhong, JC Byrd, JA Dubovsky Seminars in hematology 51 (3), 206-218, 2014 | 40 | 2014 |
The spectrum of rare central nervous system (CNS) tumors with EWSR1‐non‐ETS fusions: experience from three pediatric institutions with review of the literature O Lopez‐Nunez, B Cafferata, M Santi, S Ranganathan, TM Pearce, ... Brain pathology 31 (1), 70-83, 2021 | 38 | 2021 |
Targeting Interleukin-2-Inducible T-cell Kinase (ITK) in T-Cell Related Diseases Y Zhong, AJ Johnson, JC Byrd, JA Dubovsky Journal of Postdoctoral Research June 2 (6), 1-11, 2014 | 29 | 2014 |
AP-1 elements and TCL1 protein regulate expression of the gene encoding protein tyrosine phosphatase PTPROt in leukemia T Motiwala, N Zanesi, J Datta, S Roy, H Kutay, AM Checovich, M Kaou, ... Blood, The Journal of the American Society of Hematology 118 (23), 6132-6140, 2011 | 24 | 2011 |
Effect of increased HoxB4 on human megakaryocytic development Y Zhong, B Sullenbarger, LC Lasky Biochemical and biophysical research communications 398 (3), 377-382, 2010 | 13 | 2010 |
Genomic characterization of a PPP1CB-ALK fusion with fusion gene amplification in a congenital glioblastoma Y Zhong, F Lin, F Xu, J Schubert, J Wu, L Wainwright, X Zhao, K Cao, ... Cancer Genetics 252, 37-42, 2021 | 11 | 2021 |
Novel ATXN1/ATXN1L::NUTM2A fusions identified in aggressive infant sarcomas with gene expression and methylation patterns similar to CIC-rearranged sarcoma F Xu, AN Viaene, J Ruiz, J Schubert, J Wu, J Chen, K Cao, W Fu, ... Acta Neuropathologica Communications 10 (1), 102, 2022 | 8 | 2022 |
Identification and gene prediction of a 24 kb region containingxa5, a recessive bacterial blight resistance gene in rice (Oryza sativa L.) Y Zhong, G Jiang, X Chen, Z Xia, X Li, L Zhu, W Zhai Chinese Science Bulletin 48, 2725-2729, 2003 | 6 | 2003 |
The oncogenic roles of NTRK fusions and methods of molecular diagnosis E Aref-Eshghi, F Lin, MM Li, Y Zhong Cancer Genetics 258, 110-119, 2021 | 5 | 2021 |