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Nagendran Ramalingam
Nagendran Ramalingam
Brigham & Women's Hospital and Harvard Medical School
在 bwh.harvard.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Lipidomic analysis of α-synuclein neurotoxicity identifies stearoyl CoA desaturase as a target for Parkinson treatment
S Fanning, A Haque, T Imberdis, V Baru, MI Barrasa, S Nuber, D Termine, ...
Molecular cell 73 (5), 1001-1014. e8, 2019
2332019
Tat protein of human immunodeficiency virus type 1 subtype C strains is a defective chemokine
U Ranga, R Shankarappa, NB Siddappa, L Ramakrishna, R Nagendran, ...
Journal of virology 78 (5), 2586-2590, 2004
2112004
Phospholipids regulate localization and activity of mDia1 formin
N Ramalingam, H Zhao, D Breitsprecher, P Lappalainen, J Faix, ...
European journal of cell biology 89 (10), 723-732, 2010
862010
Loss of native α-synuclein multimerization by strategically mutating its amphipathic helix causes abnormal vesicle interactions in neuronal cells
U Dettmer, N Ramalingam, VE von Saucken, TE Kim, AJ Newman, ...
Human molecular genetics 26 (18), 3466-3481, 2017
832017
Cell models of lipid-rich α-synuclein aggregation validate known modifiers of α-synuclein biology and identify stearoyl-CoA desaturase
T Imberdis, J Negri, N Ramalingam, E Terry-Kantor, GPH Ho, S Fanning, ...
Proceedings of the National Academy of Sciences 116 (41), 20760-20769, 2019
802019
Actin-capping protein promotes microtubule stability by antagonizing the actin activity of mDia1
F Bartolini, N Ramalingam, GG Gundersen
Molecular biology of the cell 23 (20), 4032-4040, 2012
782012
An mDia1-INF2 formin activation cascade facilitated by IQGAP1 regulates stable microtubules in migrating cells
F Bartolini, L Andres-Delgado, X Qu, S Nik, N Ramalingam, L Kremer, ...
Molecular biology of the cell 27 (11), 1797-1808, 2016
622016
The actinome of Dictyostelium discoideum in comparison to actins and actin-related proteins from other organisms
JM Joseph, P Fey, N Ramalingam, XI Liu, M Rohlfs, AA Noegel, ...
PloS one 3 (7), e2654, 2008
582008
A resilient formin-derived cortical actin meshwork in the rear drives actomyosin-based motility in 2D confinement
N Ramalingam, C Franke, E Jaschinski, M Winterhoff, Y Lu, S Brühmann, ...
Nature communications 6 (1), 8496, 2015
422015
Kif4 interacts with EB1 and stabilizes microtubules downstream of Rho-mDia in migrating fibroblasts
EJ Morris, GPF Nader, N Ramalingam, F Bartolini, GG Gundersen
PloS one 9 (3), e91568, 2014
412014
Functional integrity of the contractile actin cortex is safeguarded by multiple Diaphanous-related formins
C Litschko, S Brühmann, A Csiszár, T Stephan, V Dimchev, ...
Proceedings of the National Academy of Sciences 116 (9), 3594-3603, 2019
402019
Dynamic physiological α-synuclein S129 phosphorylation is driven by neuronal activity
N Ramalingam, SX Jin, TE Moors, L Fonseca-Ornelas, K Shimanaka, ...
npj Parkinson's Disease 9 (1), 4, 2023
382023
Guanabenz promotes neuronal survival via enhancement of ATF4 and parkin expression in models of Parkinson disease
X Sun, P Aimé, D Dai, N Ramalingam, JF Crary, RE Burke, LA Greene, ...
Experimental neurology 303, 95-107, 2018
382018
Upregulation of Cellular Palmitoylation Mitigates α‐Synuclein Accumulation and Neurotoxicity
GPH Ho, N Ramalingam, T Imberdis, EC Wilkie, U Dettmer, DJ Selkoe
Movement Disorders 36 (2), 348-359, 2021
252021
Rapid alpha-synuclein toxicity in a neural cell model and its rescue by a stearoyl-CoA desaturase inhibitor
E Terry-Kantor, A Tripathi, T Imberdis, ZM LaVoie, GPH Ho, D Selkoe, ...
International journal of molecular sciences 21 (15), 5193, 2020
212020
Temperature is a key determinant of alpha-and beta-synuclein membrane interactions in neurons
N Ramalingam, U Dettmer
Journal of Biological Chemistry 296, 2021
162021
Characterization of the Ste20-like kinase Krs1 of Dictyostelium discoideum
R Arasada, H Son, N Ramalingam, L Eichinger, M Schleicher, M Rohlfs
European journal of cell biology 85 (9-10), 1059-1068, 2006
132006
Pathogenic mechanisms of cytosolic and membrane-enriched α-synuclein converge on fatty acid homeostasis
A Tripathi, H Alnakhala, E Terry-Kantor, A Newman, L Liu, T Imberdis, ...
Journal of Neuroscience 42 (10), 2116-2130, 2022
122022
Studying α-synuclein conformation by intact-cell cross-linking
T Imberdis, S Fanning, A Newman, N Ramalingam, U Dettmer
Alpha-Synuclein: Methods and Protocols, 77-91, 2019
122019
Excess membrane binding of monomeric alpha-, beta-and gamma-synuclein is invariably associated with inclusion formation and toxicity
TE Kim, AJ Newman, T Imberdis, L Brontesi, A Tripathi, N Ramalingam, ...
Human Molecular Genetics 30 (23), 2332-2346, 2021
102021
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