| Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression LS Qi, MH Larson, LA Gilbert, JA Doudna, JS Weissman, AP Arkin, ... Cell 152 (5), 1173-1183, 2013 | 5879 | 2013 |
| CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes LA Gilbert, MH Larson, L Morsut, Z Liu, GA Brar, SE Torres, ... Cell 154 (2), 442-451, 2013 | 4408 | 2013 |
| Deciphering the message in protein sequences: tolerance to amino acid substitutions JU Bowie, JF Reidhaar-Olson, WA Lim, RT Sauer Science 247 (4948), 1306-1310, 1990 | 1506 | 1990 |
| CRISPR interference (CRISPRi) for sequence-specific control of gene expression MH Larson, LA Gilbert, X Wang, WA Lim, JS Weissman, LS Qi Nature protocols 8 (11), 2180-2196, 2013 | 1473 | 2013 |
| The genome of the choanoflagellate Monosiga brevicollis and the origin of metazoans N King, MJ Westbrook, SL Young, A Kuo, M Abedin, J Chapman, ... Nature 451 (7180), 783-788, 2008 | 1249 | 2008 |
| Spatiotemporal control of cell signalling using a light-switchable protein interaction A Levskaya, OD Weiner, WA Lim, CA Voigt Nature 461 (7266), 997-1001, 2009 | 1186 | 2009 |
| Mechanism and role of PDZ domains in signaling complex assembly BZ Harris, WA Lim Journal of cell science 114 (18), 3219-3231, 2001 | 1138 | 2001 |
| The principles of engineering immune cells to treat cancer WA Lim, CH June Cell 168 (4), 724-740, 2017 | 1110 | 2017 |
| Engineering complex synthetic transcriptional programs with CRISPR RNA scaffolds JG Zalatan, ME Lee, R Almeida, LA Gilbert, EH Whitehead, M La Russa, ... Cell 160 (1), 339-350, 2015 | 1102 | 2015 |
| Defining network topologies that can achieve biochemical adaptation W Ma, A Trusina, H El-Samad, WA Lim, C Tang Cell 138 (4), 760-773, 2009 | 1057 | 2009 |
| Beyond editing: repurposing CRISPR–Cas9 for precision genome regulation and interrogation AA Dominguez, WA Lim, LS Qi Nature reviews Molecular cell biology 17 (1), 5-15, 2016 | 1053 | 2016 |
| Scaffold proteins: hubs for controlling the flow of cellular information MC Good, JG Zalatan, WA Lim Science 332 (6030), 680-686, 2011 | 1045 | 2011 |
| Precision tumor recognition by T cells with combinatorial antigen-sensing circuits KT Roybal, LJ Rupp, L Morsut, WJ Walker, KA McNally, JS Park, WA Lim Cell 164 (4), 770-779, 2016 | 999 | 2016 |
| Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription JA Doudna, M Jinek, E Charpentier, K Chylinski US Patent 10,266,850, 2019 | 953 | 2019 |
| Engineering customized cell sensing and response behaviors using synthetic notch receptors L Morsut, KT Roybal, X Xiong, RM Gordley, SM Coyle, M Thomson, ... Cell 164 (4), 780-791, 2016 | 933 | 2016 |
| Remote control of therapeutic T cells through a small molecule–gated chimeric receptor CY Wu, KT Roybal, EM Puchner, J Onuffer, WA Lim Science 350 (6258), aab4077, 2015 | 811 | 2015 |
| CRISPR/Cas9-mediated PD-1 disruption enhances anti-tumor efficacy of human chimeric antigen receptor T cells LJ Rupp, K Schumann, KT Roybal, RE Gate, CJ Ye, WA Lim, A Marson Scientific reports 7 (1), 1-10, 2017 | 743 | 2017 |
| Unexpected modes of PDZ domain scaffolding revealed by structure of nNOS-syntrophin complex BJ Hillier, KS Christopherson, KE Prehoda, DS Bredt, WA Lim Science 284 (5415), 812-815, 1999 | 694 | 1999 |
| PSD-95 Assembles a Ternary Complex with theN-Methyl-D-aspartic Acid Receptor and a Bivalent Neuronal NO Synthase PDZ Domain KS Christopherson, BJ Hillier, WA Lim, DS Bredt Journal of Biological Chemistry 274 (39), 27467-27473, 1999 | 683 | 1999 |
| Structural determinants of peptide-binding orientation and of sequence specificity in SH3 domains WA Lim, FM Richards, RO Fox Nature 372 (6504), 375-379, 1994 | 669 | 1994 |
