The spectrum of HLA-DQ and HLA-DR alleles, 2006: a listing correlating sequence and structure with function GP Bondinas, AK Moustakas, GK Papadopoulos Immunogenetics 59 (7), 539-553, 2007 | 164 | 2007 |
HLA–DR1001 presents “altered‐self” peptides derived from joint‐associated proteins by accepting citrulline in three of its binding pockets EA James, AK Moustakas, J Bui, GK Papadopoulos, G Bondinas, ... Arthritis & Rheumatism 62 (10), 2909-2918, 2010 | 128 | 2010 |
Disabling an integral CTL epitope allows suppression of autoimmune diabetes by intranasal proinsulin peptide NR Martinez, P Augstein, AK Moustakas, GK Papadopoulos, S Gregori, ... The Journal of clinical investigation 111 (9), 1365-1371, 2003 | 111 | 2003 |
Crossreactivity to vinculin and microbes provides a molecular basis for HLA-based protection against rheumatoid arthritis J Van Heemst, DTSL Jansen, S Polydorides, AK Moustakas, M Bax, ... Nature communications 6 (1), 6681, 2015 | 88 | 2015 |
Type 1 diabetes-associated HLA-DQ8 transdimer accommodates a unique peptide repertoire M van Lummel, PA van Veelen, A Zaldumbide, A de Ru, GMC Janssen, ... Journal of Biological Chemistry 287 (12), 9514-9524, 2012 | 86 | 2012 |
Large-scale characterization of natural ligands explains the unique gluten-binding properties of HLA-DQ2 D Stepniak, M Wiesner, AH de Ru, AK Moustakas, JW Drijfhout, ... The Journal of Immunology 180 (5), 3268-3278, 2008 | 84 | 2008 |
Analysis of structure and function relationships of an autoantigenic peptide of insulin bound to H-2Kd that stimulates CD8 T cells in insulin-dependent diabetes … FS Wong, AK Moustakas, L Wen, GK Papadopoulos, CA Janeway Jr Proceedings of the National Academy of Sciences 99 (8), 5551-5556, 2002 | 78 | 2002 |
Gluten-specific T cells cross-react between HLA-DQ8 and the HLA-DQ2α/DQ8β transdimer Y Kooy-Winkelaar, M van Lummel, AK Moustakas, J Schweizer, ... The Journal of Immunology 187 (10), 5123-5129, 2011 | 61 | 2011 |
Allelic variation in key peptide-binding pockets discriminates between closely related diabetes-protective and diabetes-susceptible HLA-DQB1* 06 alleles RA Ettinger, GK Papadopoulos, AK Moustakas, GT Nepom, WW Kwok The Journal of Immunology 176 (3), 1988-1998, 2006 | 61 | 2006 |
Structure of celiac disease-associated HLA-DQ8 and non-associated HLA-DQ9 alleles in complex with two disease-specific epitopes AK Moustakas, Y van de Wal, J Routsias, YMC Kooy, P van Veelen, ... International Immunology 12 (8), 1157-1166, 2000 | 60 | 2000 |
T-cell recognition of HLA-DQ2-bound gluten peptides can be influenced by an N-terminal proline at p-1 D Stepniak, LW Vader, Y Kooy, PA van Veelen, A Moustakas, ... Immunogenetics 57, 8-15, 2005 | 58 | 2005 |
Functional consequences of HLA-DQ8 homozygosity versus heterozygosity for islet autoimmunity in type 1 diabetes P Eerligh, M Van Lummel, A Zaldumbide, AK Moustakas, G Duinkerken, ... Genes & Immunity 12 (6), 415-427, 2011 | 52 | 2011 |
Molecular basis for increased susceptibility of Indigenous North Americans to seropositive rheumatoid arthritis SW Scally, SC Law, YT Ting, J Van Heemst, J Sokolove, AJ Deutsch, ... Annals of the rheumatic diseases 76 (11), 1915-1923, 2017 | 44 | 2017 |
The binding of antigenic peptides to HLA-DR is influenced by interactions between pocket 6 and pocket 9 EA James, AK Moustakas, J Bui, R Nouv, GK Papadopoulos, WW Kwok The Journal of Immunology 183 (5), 3249-3258, 2009 | 40 | 2009 |
Peptide analysis, stability studies, and structural modeling explain contradictory peptide motifs and unique properties of the NOD mouse MHC class II molecule H2‐Ag7 C Münz, M Hofmann, K Yoshida, AK Moustakas, H Kikutani, S Stevanoviç, ... European journal of immunology 32 (8), 2105-2116, 2002 | 31 | 2002 |
Molecular properties of HLA‐DQ alleles conferring susceptibility to or protection from insulin‐dependent diabetes mellitus: Keys to the fate of islet β‐cells AK Moustakas, GK Papadopoulos American journal of medical genetics 115 (1), 37-47, 2002 | 31 | 2002 |
Absorption spectra of intermolecular charge-transfer transitions between xenon and halogen molecules (fluorine, chlorine, bromine) in liquid xenon ME Fajardo, VA Apkarian, A Moustakas, H Krueger, E Weitz The Journal of Physical Chemistry 92 (2), 357-360, 1988 | 30 | 1988 |
Vibrational relaxation of HCl as a function of xenon density: The role of HCl–Xe complexes A Moustakas, E Weitz The Journal of chemical physics 98 (9), 6947-6957, 1993 | 26 | 1993 |
The increased ability to present citrullinated peptides is not unique to HLA-SE molecules: arginine-to-citrulline conversion also enhances peptide affinity for HLA-DQ molecules ASB Kampstra, J van Heemst, AK Moustakas, GK Papadopoulos, ... Arthritis research & therapy 18, 1-8, 2016 | 25 | 2016 |
Mutational analysis of critical residues determining antigen presentation and activation of HLA-DQ0602 restricted T-cell clones S Reichstetter, GK Papadopoulos, AK Moustakas, E Swanson, AW Liu, ... Human immunology 63 (3), 185-193, 2002 | 24 | 2002 |