Multi-Spectroscopic and Theoretical Analysis on the Interaction between Human Serum Albumin and a Capsaicin Derivative - RPF101 JCNF Otávio Augusto Chaves, Maurício Temotheo Tavares, Micael Rodrigues ... Biomolecules 8 (3), 78-96, 2018 | 39 | 2018 |
Oleanolic Acid (OA) as an antileishmanial agent: biological evaluation and in silico mechanistic insights TS Melo, CR Gattass, DC Soares, MR Cunha, C Ferreira, MT Tavares, ... Parasitology International 65 (3), 227–237, 2016 | 37 | 2016 |
An environmentally safe condition for the synthesis of aryl and alkyl sulphonyl hydrazones via one-pot reaction MR Cunha, MT Tavares, CF Carvalho, GJV Pereira, ADF Souza, ... ACS Sustainable Chemistry & Engineering 4 (4), 1899–1905, 2016 | 30 | 2016 |
Synthesis, molecular modeling, and evaluation of novel sulfonylhydrazones as acetylcholinesterase inhibitors for Alzheimer's disease TB Fernandes, MR Cunha, RP Sakata, TM Candido, AR Baby, ... Archiv der Pharmazie 350 (11), 1700163, 2017 | 28 | 2017 |
Inactivation-mimicking block of the epithelial calcium channel TRPV6 R Bhardwaj, S Lindinger, A Neuberger, KD Nadezhdin, AK Singh, ... Science advances 6 (48), eabe1508, 2020 | 25 | 2020 |
Natural product inspired optimization of a selective TRPV6 calcium channel inhibitor MR Cunha, R Bhardwaj, AL Carrel, S Lindinger, C Romanin, ... RSC medicinal chemistry 11 (9), 1032-1040, 2020 | 23 | 2020 |
Capsaicin-like analogue induced selective apoptosis in A2058 melanoma cells: Design, synthesis and molecular modeling GJV Pereira, MT Tavares, RA Azevedo, BB Martins, MR Cunha, ... Bioorganic & Medicinal Chemistry 27 (13), 2893-2904, 2019 | 23 | 2019 |
A Photoswitchable Inhibitor of the Calcium Channel TRPV6 MR Cunha, R Bhardwaj, S Lindinger, C Butorac, C Romanin, MA Hediger, ... ACS Medicinal Chemistry Letters 10 (9), 1341–1345, 2019 | 17 | 2019 |
Using an in Silico Approach To Teach 3D Pharmacodynamics of the Drug−Target Interaction Process Focusing on Selective COX2 Inhibition by Celecoxib MT Tavares, MC Primi, NATF Silva, CF Carvalho, MR Cunha, ... Journal of Chemical Education 94 (3), 380–387, 2017 | 14 | 2017 |
Peppers: A “Hot” Natural Source for Antitumor Compounds MR Cunha, MT Tavares, TB Fernandes, R Parise-Filho Molecules 26 (6), 1521-1542, 2021 | 12 | 2021 |
Analgesic activity of Ruta graveolens L.(Rue) extracts MR Cunha, TS Melo, FMM Magri, JC Delorenzi African J. of Pharmacy and Pharmacol 9, 1-5, 2015 | 8 | 2015 |
Discovery of novel benzothiophene derivatives as potent and narrow spectrum inhibitors of DYRK1A and DYRK1B ND Segretti, JE Takarada, MA Ferreira Jr, A da Silva Santiago, ... Bioorganic & Medicinal Chemistry Letters 68, 128764, 2022 | 3 | 2022 |
Discovery of pyrazolo [3, 4-d] pyrimidines as novel mitogen-activated protein kinase kinase 3 (MKK3) inhibitors JE Takarada, MR Cunha, VM Almeida, SNS Vasconcelos, AS Santiago, ... Bioorganic & Medicinal Chemistry 98, 117561, 2024 | 2 | 2024 |
A novel BRET-based assay to investigate binding and residence time of unmodified ligands to the human lysosomal ion channel TRPML1 in intact cells MR Cunha, CMC Catta-Preta, JE Takarada, GA Moreira, KB Massirer, ... Journal of Biological Chemistry 299 (6), 2023 | 2 | 2023 |
Novel Dihydropteridinone Derivatives As Potent Inhibitors of the Understudied Human Kinases Vaccinia-Related Kinase 1 and Casein Kinase 1δ/ε FH de Souza Gama, LA Dutra, M Hawgood, CV Dos Reis, RAM Serafim, ... Journal of Medicinal Chemistry, 2024 | 1 | 2024 |
(S)‐ML‐SA1 ACTIVATES AUTOPHAGY VIA TRPML1‐TFEB PATHWAY MR Cunha, BS do Amaral, JE Takarada, GV Valderrama, ANL Batista, ... ChemBioChem, e202400506, 2024 | | 2024 |
GATING AND MOLECULAR PHARMACOLOGY OF TRP CHANNELS A Neuberger, YA Trofimov, KD Nadezhdin, K Saotome, AK Singh, ... XXIX International Symposium" Bioinformatics and Computer-Aided Drug …, 2023 | | 2023 |