Immunosuppressive Myeloid Cells Induced by Chemotherapy Attenuate Antitumor CD4+ T-Cell Responses through the PD-1–PD-L1 Axis ZC Ding, X Lu, M Yu, H Lemos, L Huang, P Chandler, K Liu, M Walters, ... Cancer research 74 (13), 3441-3453, 2014 | 140 | 2014 |
Oxidative stress in the tumor microenvironment and its relevance to cancer immunotherapy NS Aboelella, C Brandle, T Kim, ZC Ding, G Zhou Cancers 13 (5), 986, 2021 | 107 | 2021 |
Polyfunctional CD4+ T cells are essential for eradicating advanced B-cell lymphoma after chemotherapy ZC Ding, L Huang, BR Blazar, H Yagita, AL Mellor, DH Munn, G Zhou Blood, The Journal of the American Society of Hematology 120 (11), 2229-2239, 2012 | 95 | 2012 |
Metabolic reprogramming by MYCN confers dependence on the serine-glycine-one-carbon biosynthetic pathway Y Xia, B Ye, J Ding, Y Yu, A Alptekin, M Thangaraju, PD Prasad, ZC Ding, ... Cancer research 79 (15), 3837-3850, 2019 | 82 | 2019 |
Chemotherapy rescues tumor-driven aberrant CD4+ T-cell differentiation and restores an activated polyfunctional helper phenotype ZC Ding, BR Blazar, AL Mellor, DH Munn, G Zhou Blood, The Journal of the American Society of Hematology 115 (12), 2397-2406, 2010 | 77 | 2010 |
Alteration of tumor metabolism by CD4+ T cells leads to TNF-α-dependent intensification of oxidative stress and tumor cell death T Habtetsion, ZC Ding, W Pi, T Li, C Lu, T Chen, C Xi, H Spartz, K Liu, ... Cell metabolism 28 (2), 228-242. e6, 2018 | 70 | 2018 |
Cytotoxic chemotherapy and CD4+ effector T cells: an emerging alliance for durable antitumor effects ZC Ding, G Zhou Journal of Immunology Research 2012 (1), 890178, 2012 | 67 | 2012 |
Alkylating agent melphalan augments the efficacy of adoptive immunotherapy using tumor-specific CD4+ T cells X Lu, ZC Ding, Y Cao, C Liu, T Habtetsion, M Yu, H Lemos, H Salman, ... The Journal of Immunology 194 (4), 2011-2021, 2015 | 65 | 2015 |
The impact of antibiotic usage on the efficacy of chemoimmunotherapy is contingent on the source of tumor-reactive T cells MP Kuczma, ZC Ding, T Li, T Habtetsion, T Chen, Z Hao, L Bryan, N Singh, ... Oncotarget 8 (67), 111931, 2017 | 60 | 2017 |
Presentation of acquired peptide-MHC class II ligands by CD4+ regulatory T cells or helper cells differentially regulates antigen-specific CD4+ T cell response G Zhou, ZC Ding, J Fu, HI Levitsky The Journal of Immunology 186 (4), 2148-2155, 2011 | 57 | 2011 |
Persistent STAT5 activation reprograms the epigenetic landscape in CD4+ T cells to drive polyfunctionality and antitumor immunity ZC Ding, H Shi, NS Aboelella, K Fesenkova, EJ Park, Z Liu, L Pei, J Li, ... Science immunology 5 (52), eaba5962, 2020 | 53 | 2020 |
The stress-responsive gene ATF3 regulates the histone acetyltransferase Tip60 H Cui, M Guo, D Xu, ZC Ding, G Zhou, HF Ding, J Zhang, Y Tang, C Yan Nature communications 6 (1), 6752, 2015 | 50 | 2015 |
Chemotherapy-induced myeloid suppressor cells and antitumor immunity: The Janus face of chemotherapy in immunomodulation ZC Ding, DH Munn, G Zhou Oncoimmunology 3 (8), e954471, 2014 | 41 | 2014 |
Neuronal growth‐inhibitory factor (metallothionein‐3): structure–function relationships ZC Ding, FY Ni, ZX Huang The FEBS journal 277 (14), 2912-2920, 2010 | 41 | 2010 |
Structural prediction of the β‐domain of metallothionein‐3 by molecular dynamics simulation FY Ni, B Cai, ZC Ding, F Zheng, MJ Zhang, HM Wu, HZ Sun, ZX Huang Proteins: Structure, Function, and Bioinformatics 68 (1), 255-266, 2007 | 40 | 2007 |
Immunostimulatory effects of melphalan and usefulness in adoptive cell therapy with antitumor CD4+ T cells M Kuczma, ZC Ding, G Zhou Critical Reviews™ in Immunology 36 (2), 2016 | 33 | 2016 |
Adjuvant IL-7 potentiates adoptive T cell therapy by amplifying and sustaining polyfunctional antitumor CD4+ T cells ZC Ding, T Habtetsion, Y Cao, T Li, C Liu, M Kuczma, T Chen, Z Hao, ... Scientific reports 7 (1), 12168, 2017 | 29 | 2017 |
The molecular mechanism for human metallothionein-3 to protect against the neuronal cytotoxicity of Aβ1–42 with Cu ions Y Luo, Y Xu, Q Bao, Z Ding, C Zhu, ZX Huang, X Tan JBIC Journal of Biological Inorganic Chemistry 18, 39-47, 2013 | 29 | 2013 |
IL-7 signaling imparts polyfunctionality and stemness potential to CD4+ T cells ZC Ding, C Liu, Y Cao, T Habtetsion, M Kuczma, W Pi, H Kong, E Cacan, ... Oncoimmunology 5 (6), e1171445, 2016 | 25 | 2016 |
Mutation at Glu23 eliminates the neuron growth inhibitory activity of human metallothionein-3 ZC Ding, XC Teng, B Cai, H Wang, Q Zheng, Y Wang, GM Zhou, ... Biochemical and Biophysical Research Communications 349 (2), 674-682, 2006 | 24 | 2006 |