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Wouter P.R. Verdurmen
Wouter P.R. Verdurmen
Assistant Professor, Radboud University Medical Center
在 radboudumc.nl 的电子邮件经过验证 - 首页
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引用次数
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Protein expression from exogenous mRNA: Uptake by receptor-mediated endocytosis and trafficking via the lysosomal pathway
C Lorenz, M Fotin-Mleczek, G Roth, C Becker, TC Dam, WPR Verdurmen, ...
RNA biology 8 (4), 627-636, 2011
2012011
Molecular parameters of siRNA–cell penetrating peptide nanocomplexes for efficient cellular delivery
AH van Asbeck, A Beyerle, H McNeill, PHM Bovee-Geurts, S Lindberg, ...
ACS nano 7 (5), 3797-3807, 2013
1682013
Cellular integration of an enzyme-loaded polymersome nanoreactor
SFM Van Dongen, WPR Verdurmen, R Peters, RJM Nolte, R Brock, ...
Angew. Chem., Int. Ed 49 (40), 7213-7216, 2010
1652010
Preferential uptake of L-versus D-amino acid cell-penetrating peptides in a cell type-dependent manner
WPR Verdurmen, PH Bovee-Geurts, P Wadhwani, AS Ulrich, M Hällbrink, ...
Chemistry & biology 18 (8), 1000-1010, 2011
1562011
A cell-penetrating peptide derived from human lactoferrin with conformation-dependent uptake efficiency
F Duchardt, IR Ruttekolk, WPR Verdurmen, H Lortat-Jacob, J Bürck, ...
Journal of Biological Chemistry 284 (52), 36099-36108, 2009
1512009
Cationic cell-penetrating peptides induce ceramide formation via acid sphingomyelinase: implications for uptake
WPR Verdurmen, M Thanos, IR Ruttekolk, E Gulbins, R Brock
Journal of Controlled Release 147 (2), 171-179, 2010
1232010
Biological responses towards cationic peptides and drug carriers
WPR Verdurmen, R Brock
Trends in pharmacological sciences 32 (2), 116-124, 2011
1062011
A quantitative comparison of cytosolic delivery via different protein uptake systems
WPR Verdurmen, M Mazlami, A Plückthun
Scientific reports 7 (1), 13194, 2017
982017
Functional consequences of sphingomyelinase-induced changes in erythrocyte membrane structure
S Dinkla, K Wessels, WPR Verdurmen, C Tomelleri, JCA Cluitmans, ...
Cell death & disease 3 (10), e410-e410, 2012
892012
Efficient cell-specific uptake of binding proteins into the cytoplasm through engineered modular transport systems
WPR Verdurmen, M Luginbühl, A Honegger, A Plückthun
Journal of Controlled Release 200, 13-22, 2015
842015
The stoichiometry of peptide-heparan sulfate binding as a determinant of uptake efficiency of cell-penetrating peptides
R Wallbrecher, WPR Verdurmen, S Schmidt, PH Bovee-Geurts, ...
Cellular and molecular life sciences 71, 2717-2729, 2014
682014
Structure analysis and conformational transitions of the cell penetrating peptide transportan 10 in the membrane-bound state
S Fanghänel, P Wadhwani, E Strandberg, WPR Verdurmen, J Bürck, ...
PLoS One 9 (6), e99653, 2014
592014
Mimicking Tumors: Toward More Predictive In Vitro Models for Peptide- and Protein-Conjugated Drugs
D van den Brand, LF Massuger, R Brock, WPR Verdurmen
Bioconjugate chemistry 28 (3), 846-856, 2017
542017
Cell surface clustering of heparan sulfate proteoglycans by amphipathic cell-penetrating peptides does not contribute to uptake
WPR Verdurmen, R Wallbrecher, S Schmidt, J Eilander, P Bovee-Geurts, ...
Journal of controlled release 170 (1), 83-91, 2013
502013
Intermolecular biparatopic trapping of ErbB2 prevents compensatory activation of PI3K/AKT via RAS–p110 crosstalk
R Tamaskovic, M Schwill, G Nagy-Davidescu, C Jost, DC Schaefer, ...
Nature Communications 7 (1), 11672, 2016
472016
Metabolic switching of tumor cells under hypoxic conditions in a tumor-on-a-chip model
V Palacio-Castañeda, L Kooijman, B Venzac, WPR Verdurmen, S Le Gac
Micromachines 11 (4), 382, 2020
462020
Detecting cytosolic peptide delivery with the GFP complementation assay in the low micromolar range
S Schmidt, MJW Adjobo‐Hermans, R Wallbrecher, WPR Verdurmen, ...
Angewandte Chemie International Edition 54 (50), 15105-15108, 2015
432015
Exploration of the design principles of a cell-penetrating bicylic peptide scaffold
R Wallbrecher, L Depré, WPR Verdurmen, PH Bovée-Geurts, ...
Bioconjugate chemistry 25 (5), 955-964, 2014
432014
Oxygen control: the often overlooked but essential piece to create better in vitro systems
V Palacio-Castañeda, N Velthuijs, S Le Gac, WPR Verdurmen
Lab on a Chip 22 (6), 1068-1092, 2022
362022
Multivalent presentation of the cell-penetrating peptide nona-arginine on a linear scaffold strongly increases its membrane-perturbing capacity
A Chakrabarti, JJ Witsenburg, MD Sinzinger, M Richter, R Wallbrecher, ...
Biochimica et Biophysica Acta (BBA)-Biomembranes 1838 (12), 3097-3106, 2014
312014
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