Structure of the class D GPCR Ste2 dimer coupled to two G proteins V Velazhahan, N Ma, G Pándy-Szekeres, AJ Kooistra, Y Lee, DE Gloriam, ... Nature 589 (7840), 148-153, 2021 | 75 | 2021 |
IFITM3 functions as a PIP3 scaffold to amplify PI3K signalling in B cells J Lee, ME Robinson, N Ma, D Artadji, MA Ahmed, G Xiao, T Sadras, ... Nature 588 (7838), 491-497, 2020 | 70 | 2020 |
De Novo Left‐Handed Synthetic Peptidomimetic Foldamers F She, P Teng, A Peguero‐Tejada, M Wang, N Ma, T Odom, M Zhou, ... Angewandte Chemie 130 (31), 10064-10068, 2018 | 56 | 2018 |
Right-Handed Helical Foldamers Consisting of De Novo d-AApeptides P Teng, N Ma, DC Cerrato, F She, T Odom, X Wang, LJ Ming, ... Journal of the American Chemical Society 139 (21), 7363-7369, 2017 | 54 | 2017 |
Photophysical and dynamical properties of doubly linked Cy3–DNA constructs EMS Stennett, N Ma, A Van Der Vaart, M Levitus The Journal of Physical Chemistry B 118 (1), 152-163, 2014 | 54 | 2014 |
Structural basis of odorant recognition by a human odorant receptor CB Billesbølle, CA de March, WJC van der Velden, N Ma, J Tewari, ... Nature 615 (7953), 742-749, 2023 | 49 | 2023 |
Modeling, synthesis, and biological evaluation of potential retinoid X receptor (RXR) selective agonists: novel analogues of 4-[1-(3, 5, 5, 8, 8-pentamethyl-5, 6, 7, 8 … PW Jurutka, I Kaneko, J Yang, JS Bhogal, JC Swierski, CR Tabacaru, ... Journal of medicinal chemistry 56 (21), 8432-8454, 2013 | 31 | 2013 |
Autoregulation of GPCR signalling through the third intracellular loop F Sadler, N Ma, M Ritt, Y Sharma, N Vaidehi, S Sivaramakrishnan Nature 615 (7953), 734-741, 2023 | 30 | 2023 |
Anisotropy of B-DNA groove bending N Ma, A van der Vaart Journal of the American Chemical Society 138 (31), 9951-9958, 2016 | 30 | 2016 |
Dynamic spatiotemporal determinants modulate GPCR: G protein coupling selectivity and promiscuity M Sandhu, A Cho, N Ma, E Mukhaleva, Y Namkung, S Lee, S Ghosh, ... Nature Communications 13 (1), 7428, 2022 | 26 | 2022 |
Allosteric communication regulates ligand‐specific GPCR activity N Ma, AK Nivedha, N Vaidehi The FEBS journal 288 (8), 2502-2512, 2021 | 26 | 2021 |
Analysis of differential secondary effects of novel rexinoids: select rexinoid X receptor ligands demonstrate differentiated side effect profiles PA Marshall, PW Jurutka, CE Wagner, A van der Vaart, I Kaneko, ... Pharmacology research & perspectives 3 (2), e00122, 2015 | 21 | 2015 |
Free energy coupling between DNA bending and base flipping N Ma, A van der Vaart Journal of Chemical Information and Modeling 57 (8), 2020-2026, 2017 | 20 | 2017 |
Modeling, synthesis, and biological evaluation of potential retinoid X receptor (RXR)-selective agonists: analogues of 4-[1-(3, 5, 5, 8, 8-pentamethyl-5, 6, 7, 8-tetrahydro-2 … MC Heck, CE Wagner, PH Shahani, M MacNeill, A Grozic, T Darwaiz, ... Journal of medicinal chemistry 59 (19), 8924-8940, 2016 | 20 | 2016 |
Activation mechanism of the class D fungal GPCR dimer Ste2 V Velazhahan, N Ma, N Vaidehi, CG Tate Nature 603 (7902), 743-748, 2022 | 19 | 2022 |
Activation Microswitches in Adenosine Receptor A2A Function as Rheostats in the Cell Membrane N Ma, S Lee, N Vaidehi Biochemistry 59 (42), 4059-4071, 2020 | 14 | 2020 |
Bitopic inhibition of ATP and substrate binding in Ser/Thr kinases through a conserved allosteric mechanism N Ma, LG Lippert, T Devamani, B Levy, S Lee, M Sandhu, N Vaidehi, ... Biochemistry 57 (45), 6387-6390, 2018 | 12 | 2018 |
A novel gene expression analytics-based approach to structure aided design of rexinoids for development as next-generation cancer therapeutics BJ Hanish, JFH Price, I Kaneko, N Ma, A van der Vaart, CE Wagner, ... Steroids 135, 36-49, 2018 | 10 | 2018 |
Molecular dynamics simulations and molecular flooding studies of the retinoid X-receptor ligand binding domain GM Gray, N Ma, CE Wagner, A van der Vaart Journal of molecular modeling 23, 1-9, 2017 | 9 | 2017 |
Catalytic site mutations confer multiple states of G protein activation N Hewitt, N Ma, N Arang, SA Martin, A Prakash, JF DiBerto, KM Knight, ... Science signaling 16 (772), eabq7842, 2023 | 6 | 2023 |