Mevalonate kinase deficiency leads to decreased prenylation of Rab GTPases J Jurczyluk, MA Munoz, OP Skinner, RC Chai, N Ali, U Palendira, ... Immunology and Cell Biology 94 (10), 994-999, 2016 | 41 | 2016 |
A highly sensitive prenylation assay reveals in vivo effects of bisphosphonate drug on the Rab prenylome of macrophages outside the skeleton N Ali, J Jurczyluk, G Shay, Z Tnimov, K Alexandrov, MA Munoz, ... Small GTPases 6 (4), 202-211, 2015 | 33 | 2015 |
Lack of protein prenylation promotes NLRP3 inflammasome assembly in human monocytes OP Skinner, J Jurczyluk, PJ Baker, SL Masters, AGR Wilks, ... Journal of Allergy and Clinical Immunology 143 (6), 2315-2317. e3, 2019 | 21 | 2019 |
Bisphosphonate drugs have actions in the lung and inhibit the mevalonate pathway in alveolar macrophages MA Munoz, EK Fletcher, OP Skinner, J Jurczyluk, E Kristianto, MP Hodson, ... Elife 10, e72430, 2021 | 12 | 2021 |
Increased core body temperature exacerbates defective protein prenylation in mouse models of mevalonate kinase deficiency MA Munoz, OP Skinner, E Masle-Farquhar, J Jurczyluk, Y Xiao, ... The Journal of Clinical Investigation 132 (19), 2022 | 4 | 2022 |
Systemic host inflammation induces stage-specific transcriptomic modification and slower maturation in malaria parasites LIM Lansink, OP Skinner, JA Engel, HJ Lee, MSF Soon, CG Williams, ... Mbio 14 (4), e01129-23, 2023 | 3 | 2023 |
Plasmodium infection induces phenotypic, clonal, and spatial diversity among differentiating CD4+ T cells CG Williams, ML Moreira, T Asatsuma, HJ Lee, S Li, I Barrera, E Murray, ... Cell Reports 43 (6), 2024 | 2 | 2024 |
Advances and challenges in investigating B-cells via single-cell transcriptomics OP Skinner, S Asad, A Haque Current Opinion in Immunology 88, 102443, 2024 | 1 | 2024 |
Spatial transcriptomics maps molecular and cellular requirements for CD4+ T cell-dependent immunity to malaria CG Williams, ML Moreira, T Asatsuma, OP Skinner, HJ Lee, S Li, I Barrera, ... bioRxiv, 2023.02. 23.529309, 2023 | 1 | 2023 |
CD4+ T cells display a spectrum of recall dynamics during re-infection with malaria parasites HJ Lee, ML Moreira, S Li, T Asatsuma, CG Williams, OP Skinner, S Asad, ... Nature Communications 15 (1), 5497, 2024 | | 2024 |
Increased core body temperature exacerbates defective protein prenylation in mouse avatars of mevalonate kinase deficiency MA Munoz, OP Skinner, E Masle-Farquhar, J Jurczyluk, Y Xiao, E Fletcher, ... bioRxiv, 2022.02. 28.480959, 2022 | | 2022 |
Bisphosphonate drugs have actions outside the skeleton and inhibit the mevalonate pathway in alveolar macrophages MA Munoz, EK Fletcher, OP Skinner, J Jurczyluk, E Kristianto, MP Hodson, ... bioRxiv, 2021.08. 09.455652, 2021 | | 2021 |
New insights into the link between protein prenylation and inflammation using models of mevalonate kinase deficiency (MKD) O Skinner UNSW Sydney, 2021 | | 2021 |
Protein prenylation is defective in mevalonate kinase deficiency and is an accurate biomarker in peripheral blood mononuclear cells D Coman, M Munoz, M Rogers, J Jurczyluk, O Skinner, A Simon, S Mehr, ... Pediatric Rheumatology, 2019 | | 2019 |