Mevalonate kinase deficiency leads to decreased prenylation of Rab GTPases J Jurczyluk, MA Munoz, OP Skinner, RC Chai, N Ali, U Palendira, ... Immunology and Cell Biology 94 (10), 994-999, 2016 | 38 | 2016 |
A highly sensitive prenylation assay reveals in vivo effects of bisphosphonate drug on the Rab prenylome of macrophages outside the skeleton N Ali, J Jurczyluk, G Shay, Z Tnimov, K Alexandrov, MA Munoz, ... Small GTPases 6 (4), 202-211, 2015 | 32 | 2015 |
Lack of protein prenylation promotes NLRP3 inflammasome assembly in human monocytes OP Skinner, J Jurczyluk, PJ Baker, SL Masters, AGR Wilks, ... Journal of Allergy and Clinical Immunology 143 (6), 2315-2317. e3, 2019 | 18 | 2019 |
Bisphosphonate drugs have actions in the lung and inhibit the mevalonate pathway in alveolar macrophages MA Munoz, EK Fletcher, OP Skinner, J Jurczyluk, E Kristianto, MP Hodson, ... Elife 10, e72430, 2021 | 6 | 2021 |
Systemic host inflammation induces stage-specific transcriptomic modification and slower maturation in malaria parasites LIM Lansink, OP Skinner, JA Engel, HJ Lee, MSF Soon, CG Williams, ... Mbio 14 (4), e01129-23, 2023 | | 2023 |
CD4+ T cells display a spectrum of recall dynamics during re-infection with malaria parasites. HJ Lee, ML Moreira, S Li, CG Williams, OP Skinner, S Asad, T Asatsuma, ... bioRxiv, 2023.03. 02.530907, 2023 | | 2023 |
Spatial transcriptomics maps molecular and cellular requirements for CD4+ T cell-dependent immunity to malaria. CG Williams, ML Moreira, T Asatsuma, OP Skinner, HJ Lee, S Li, I Barrera, ... bioRxiv, 2023.02. 23.529309, 2023 | | 2023 |
Increased core body temperature exacerbates defective protein prenylation in mouse models of mevalonate kinase deficiency MA Munoz, OP Skinner, E Masle-Farquhar, J Jurczyluk, Y Xiao, ... Journal of Clinical Investigation 132 (19), e160929, 2022 | | 2022 |
Increased core body temperature exacerbates defective protein prenylation in mouse avatars of mevalonate kinase deficiency MA Munoz, OP Skinner, E Masle-Farquhar, J Jurczyluk, Y Xiao, E Fletcher, ... bioRxiv, 2022.02. 28.480959, 2022 | | 2022 |
Bisphosphonate drugs have actions outside the skeleton and inhibit the mevalonate pathway in alveolar macrophages MA Munoz, EK Fletcher, OP Skinner, J Jurczyluk, E Kristianto, MP Hodson, ... bioRxiv, 2021.08. 09.455652, 2021 | | 2021 |
New insights into the link between protein prenylation and inflammation using models of mevalonate kinase deficiency (MKD) O Skinner UNSW Sydney, 2021 | | 2021 |