The Pseudomonas aeruginosa Pan-Genome Provides New Insights on Its Population Structure, Horizontal Gene Transfer, and Pathogenicity L Freschi, AT Vincent, J Jeukens, JG Emond-Rheault, I Kukavica-Ibrulj, ... Genome biology and evolution 11 (1), 109-120, 2019 | 234 | 2019 |
Clinical utilization of genomics data produced by the international Pseudomonas aeruginosa consortium L Freschi, J Jeukens, I Kukavica-Ibrulj, B Boyle, MJ Dupont, J Laroche, ... Frontiers in microbiology 6, 1036, 2015 | 152 | 2015 |
GWAS for quantitative resistance phenotypes in Mycobacterium tuberculosis reveals resistance genes and regulatory regions MR Farhat, L Freschi, R Calderon, T Ioerger, M Snyder, CJ Meehan, ... Nature communications 10 (1), 2128, 2019 | 117 | 2019 |
Beyond multidrug resistance: Leveraging rare variants with machine and statistical learning models in Mycobacterium tuberculosis resistance prediction ML Chen, A Doddi, J Royer, L Freschi, M Schito, M Ezewudo, IS Kohane, ... EBioMedicine 43, 356-369, 2019 | 86* | 2019 |
Genomics of antibiotic‐resistance prediction in Pseudomonas aeruginosa J Jeukens, L Freschi, I Kukavica‐Ibrulj, JG Emond‐Rheault, NP Tucker, ... Annals of the New York Academy of Sciences 1435 (1), 5-17, 2019 | 67 | 2019 |
Genomic characterisation of an international Pseudomonas aeruginosa reference panel indicates that the two major groups draw upon distinct mobile gene pools L Freschi, C Bertelli, J Jeukens, MP Moore, I Kukavica-Ibrulj, ... FEMS microbiology letters 365 (14), fny120, 2018 | 65 | 2018 |
Population structure, biogeography and transmissibility of Mycobacterium tuberculosis L Freschi, R Vargas Jr, A Husain, SMM Kamal, A Skrahina, S Tahseen, ... Nature communications 12 (1), 6099, 2021 | 58 | 2021 |
Comparative genomics and biological characterization of sequential Pseudomonas aeruginosa isolates from persistent airways infection I Bianconi, J Jeukens, L Freschi, B Alcalá-Franco, M Facchini, B Boyle, ... BMC genomics 16 (1), 1-13, 2015 | 52 | 2015 |
Comparative genomics of a drug-resistant Pseudomonas aeruginosa panel and the challenges of antimicrobial resistance prediction from genomes J Jeukens, I Kukavica-Ibrulj, JG Emond-Rheault, L Freschi, RC Levesque FEMS Microbiology Letters 364 (18), fnx161, 2017 | 51 | 2017 |
Turnover of protein phosphorylation evolving under stabilizing selection CR Landry, L Freschi, T Zarin, AM Moses Frontiers in genetics 5, 245, 2014 | 49 | 2014 |
A Pan-Genomic Approach to Understand the Basis of Host Adaptation in Achromobacter J Jeukens, L Freschi, AT Vincent, JG Emond-Rheault, I Kukavica-Ibrulj, ... Genome Biology and Evolution 9 (4), 1030-1046, 2017 | 48 | 2017 |
Increasing genomic diversity and evidence of constrained lifestyle evolution due to insertion sequences in Aeromonas salmonicida AT Vincent, MV Trudel, L Freschi, V Nagar, C Gagné-Thivierge, ... BMC genomics 17 (1), 1-12, 2016 | 47 | 2016 |
Functional divergence and evolutionary turnover in mammalian phosphoproteomes L Freschi, M Osseni, CR Landry PLoS genetics 10 (1), e1004062, 2014 | 47 | 2014 |
Salmonella enterica Prophage Sequence Profiles Reflect Genome Diversity and Can Be Used for High Discrimination Subtyping W Mottawea, MO Duceppe, AA Dupras, V Usongo, J Jeukens, L Freschi, ... Frontiers in microbiology 9, 836, 2018 | 43 | 2018 |
Characterization of spindle checkpoint kinase Mps1 reveals domain with functional and structural similarities to tetratricopeptide repeat motifs of Bub1 and BubR1 checkpoint … S Lee, P Thebault, L Freschi, S Beaufils, TL Blundell, CR Landry, ... Journal of Biological Chemistry 287 (8), 5988-6001, 2012 | 41 | 2012 |
A Multi-Species TaqMan PCR Assay for the Identification of Asian Gypsy Moths (Lymantria spp.) and Other Invasive Lymantriines of Biosecurity Concern to North … D Stewart, R Zahiri, A Djoumad, L Freschi, J Lamarche, D Holden, ... PloS one 11 (8), e0160878, 2016 | 40 | 2016 |
qPCA: a scalable assay to measure the perturbation of protein–protein interactions in living cells L Freschi, F Torres-Quiroz, AK Dubé, CR Landry Molecular BioSystems, 2013 | 40 | 2013 |
Phosphorylation network rewiring by gene duplication L Freschi, M Courcelles, P Thibault, SW Michnick, CR Landry Molecular systems biology 7 (1), 504, 2011 | 40 | 2011 |
Role of epistasis in amikacin, kanamycin, bedaquiline, and clofazimine resistance in Mycobacterium tuberculosis complex R Vargas Jr, L Freschi, A Spitaleri, S Tahseen, I Barilar, S Niemann, ... Antimicrobial Agents and Chemotherapy 65 (11), 10.1128/aac. 01164-21, 2021 | 39 | 2021 |
Comparative analysis of mitochondrial genomes of geographic variants of the gypsy moth, Lymantria dispar, reveals a previously undescribed genotypic entity A Djoumad, A Nisole, R Zahiri, L Freschi, S Picq, DE Gundersen-Rindal, ... Scientific Reports 7 (1), 14245, 2017 | 38 | 2017 |