HLTF’s ancient HIRAN domain binds 3′ DNA ends to drive replication fork reversal AC Kile, DA Chavez, J Bacal, S Eldirany, DM Korzhnev, I Bezsonova, ... Molecular cell 58 (6), 1090-1100, 2015 | 214 | 2015 |
HLTF promotes fork reversal, limiting replication stress resistance and preventing multiple mechanisms of unrestrained DNA synthesis G Bai, C Kermi, H Stoy, CJ Schiltz, J Bacal, AM Zaino, MK Hadden, ... Molecular cell 78 (6), 1237-1251. e7, 2020 | 153 | 2020 |
Cohesin association to replication sites depends on rad50 and promotes fork restart M Tittel-Elmer, A Lengronne, MB Davidson, J Bacal, P François, M Hohl, ... Molecular cell 48 (1), 98-108, 2012 | 136 | 2012 |
The histone deacetylases sir2 and rpd3 act on ribosomal DNA to control the replication program in budding yeast K Yoshida, J Bacal, D Desmarais, I Padioleau, O Tsaponina, A Chabes, ... Molecular cell 54 (4), 691-697, 2014 | 122 | 2014 |
Analysis of DNA replication profiles in budding yeast and mammalian cells using DNA combing JN Bianco, J Poli, J Saksouk, J Bacal, MJ Silva, K Yoshida, YL Lin, ... Methods 57 (2), 149-157, 2012 | 121 | 2012 |
Histone H3 lysine 56 acetylation and the response to DNA replication fork damage H Wurtele, GS Kaiser, J Bacal, E St-Hilaire, EH Lee, S Tsao, J Dorn, ... Molecular and cellular biology, 2012 | 109 | 2012 |
Mrc1 and Rad9 cooperate to regulate initiation and elongation of DNA replication in response to DNA damage J Bacal, M Moriel‐Carretero, B Pardo, A Barthe, S Sharma, A Chabes, ... The EMBO journal 37 (21), e99319, 2018 | 67 | 2018 |
DNA replication stress underlies renal phenotypes in CEP290-associated Joubert syndrome GG Slaats, JC Saldivar, J Bacal, MK Zeman, AC Kile, AM Hynes, ... The Journal of clinical investigation 125 (9), 3657-3666, 2015 | 62 | 2015 |
Phosphorylation of CMG helicase and Tof1 is required for programmed fork arrest D Bastia, P Srivastava, S Zaman, M Choudhury, BK Mohanty, J Bacal, ... Proceedings of the National Academy of Sciences 113 (26), E3639-E3648, 2016 | 35 | 2016 |
Signaling by the integrated stress response kinase PKR is fine-tuned by dynamic clustering F Zappa, NL Muniozguren, MZ Wilson, MS Costello, JC Ponce-Rojas, ... Journal of Cell Biology 221 (7), e202111100, 2022 | 29 | 2022 |
Eliminating hypoxic tumor cells improves response to PARP inhibitors in homologous recombination–deficient cancer models M Mehibel, Y Xu, CG Li, EJ Moon, KN Thakkar, AN Diep, RK Kim, ... The Journal of clinical investigation 131 (11), 2021 | 21 | 2021 |
Interstrand crosslinking of homologous repair template DNA enhances gene editing in human cells HI Ghasemi, J Bacal, AC Yoon, KU Tavasoli, C Cruz, JT Vu, BM Gardner, ... Nature biotechnology 41 (10), 1398-1404, 2023 | 3 | 2023 |
A genome-wide screen links peroxisome regulation with Wnt signaling through RNF146 and TNKS/2 JT Vu, KU Tavasoli, CJ Sheedy, SP Chowdhury, L Mandjikian, J Bacal, ... Journal of Cell Biology 223 (10), 2024 | | 2024 |
Baseline unfolded protein response signaling adjusts the timing of the mammalian cell cycle SP Chowdhury, SC Solley, E Polishchuk, J Bacal, JE Conrad, ... Molecular Biology of the Cell 35 (6), br12, 2024 | | 2024 |
Abstract 2189 A genome-wide screen identifies novel regulators of peroxisome biology B Gardner, J Vu, K Tavasoli, J Bacal, M Morrissey, C Richardson Journal of Biological Chemistry 300 (3), 2024 | | 2024 |
Abstract 1127 FANCD2 promotes HR outcomes during DSB repair by stabilizing template and DSB molecules C Richardson, C Joyce, J Bacal Journal of Biological Chemistry 300 (3), 2024 | | 2024 |
A genome-wide screen links peroxisome regulation with Wnt signaling through RNF146 and tankyrase JT Vu, KU Tavasoli, L Mandjikian, CJ Sheedy, J Bacal, MA Morrissey, ... bioRxiv, 2024 | | 2024 |
Abstract IA-003: Oxygen dependent resistance to PARP inhibitors M Mehibel, J Xu, G Li, J Moon, K Thakkar, A Diep, R Kim, J Bloomstein, ... Clinical Cancer Research 27 (8_Supplement), IA-003-IA-003, 2021 | | 2021 |