| Global network reorganization during dynamic adaptations of Bacillus subtilis metabolism JM Buescher, W Liebermeister, M Jules, M Uhr, J Muntel, E Botella, ... Science 335 (6072), 1099-1103, 2012 | 331 | 2012 |
| Large‐scale 13C‐flux analysis reveals distinct transcriptional control of respiratory and fermentative metabolism in Escherichia coli BRB Haverkorn van Rijsewijk, A Nanchen, S Nallet, RJ Kleijn, U Sauer Molecular systems biology 7 (1), 477, 2011 | 219 | 2011 |
| Transcriptional regulation is insufficient to explain substrate‐induced flux changes in Bacillus subtilis V Chubukov, M Uhr, L Le Chat, RJ Kleijn, M Jules, H Link, S Aymerich, ... Molecular systems biology 9 (1), 709, 2013 | 214 | 2013 |
| Metabolic-flux analysis of Saccharomyces cerevisiae CEN.PK113-7D based on mass isotopomer measurements of 13C-labeled primary metabolites WA Van Winden, JC Van Dam, C Ras, RJ Kleijn, JL Vinke, WM Van Gulik, ... FEMS yeast research 5 (6-7), 559-568, 2005 | 205 | 2005 |
| Metabolic fluxes during strong carbon catabolite repression by malate in Bacillus subtilis RJ Kleijn, JM Buescher, L Le Chat, M Jules, S Aymerich, U Sauer Journal of Biological Chemistry 285 (3), 1587-1596, 2010 | 153 | 2010 |
| Regulatory tasks of the phosphoenolpyruvate-phosphotransferase system of Pseudomonas putida in central carbon metabolism M Chavarría, RJ Kleijn, U Sauer, K Pflüger-Grau, V de Lorenzo MBio 3 (2), 10.1128/mbio. 00028-12, 2012 | 88 | 2012 |
| Metabolic flux analysis of a glycerol-overproducing Saccharomyces cerevisiae strain based on GC-MS, LC-MS and NMR-derived 13C-labelling data RJ Kleijn, JMA Geertman, BK Nfor, C Ras, D Schipper, JT Pronk, ... FEMS Yeast Research 7 (2), 216-231, 2007 | 83 | 2007 |
| Regulation of CodY activity through modulation of intracellular branched-chain amino acid pools SR Brinsmade, RJ Kleijn, U Sauer, AL Sonenshein Journal of bacteriology 192 (24), 6357-6368, 2010 | 81 | 2010 |
| Measurement of intracellular metabolites of primary metabolism and adenine nucleotides in chemostat cultivated Penicillium chrysogenum U Nasution, WM Van Gulik, RJ Kleijn, WA Van Winden, A Proell, ... Biotechnology and Bioengineering 94 (1), 159-166, 2006 | 79 | 2006 |
| Revisiting the 13C‐label distribution of the non‐oxidative branch of the pentose phosphate pathway based upon kinetic and genetic evidence RJ Kleijn, WA Van Winden, WM Van Gulik, JJ Heijnen The FEBS journal 272 (19), 4970-4982, 2005 | 68 | 2005 |
| Cytosolic NADPH metabolism in penicillin-G producing and non-producing chemostat cultures of Penicillium chrysogenum RJ Kleijn, F Liu, WA van Winden, WM van Gulik, C Ras, JJ Heijnen Metabolic Engineering 9 (1), 112-123, 2007 | 66 | 2007 |
| Development of In Vivo Sponge Cultures: Particle Feeding by the Tropical Sponge Pseudosuberites aff. andrewsi R Osinga, R Kleijn, E Groenendijk, P Niesink, J Tramper, RH Wijffels Marine Biotechnology 3, 544-554, 2001 | 58 | 2001 |
| 13C-Labeled Gluconate Tracing as a Direct and Accurate Method for Determining the Pentose Phosphate Pathway Split Ratio in Penicillium chrysogenum RJ Kleijn, WA van Winden, C Ras, WM van Gulik, D Schipper, JJ Heijnen Applied and Environmental Microbiology 72 (7), 4743-4754, 2006 | 56 | 2006 |
| The IHF regulon of exponentially growing Pseudomonas putida cells R Silva‐Rocha, M Chavarría, RJ Kleijn, U Sauer, V de Lorenzo Environmental microbiology 15 (1), 49-63, 2013 | 20 | 2013 |
| Development and application of 13C-labeling techniques: analyzing the pentose phosphate pathway of Penicillium chrysogenum RJ Kleijn | 4 | 2007 |
| Behavior of Enterobacter pulveris in amorphous and crystalline powder matrices treated with supercritical carbon dioxide M Callanan, M Paes, C Iversen, R Kleijn, CB Almeida, W Peñaloza, ... Journal of dairy science 95 (11), 6300-6306, 2012 | 2 | 2012 |
| Transcriptional control of metabolic fluxes and computational identification of the governing principles RJ Kleijn, SM Fendt, R Schuetz, M Heinemann, N Zamboni, U Sauer The FEBS Journal 277, 27-27, 2010 | 1 | 2010 |
| Use of AEX-HPLC-ESI-MS for 13C-labeling based metabolic flux analysis in Saccharomyces cerevisiae and Penicillium chrysogenum WA van Winden, RJ Kleijn, WM van Gulik, JJ Heijnen The metabolic pathway engineering handbook: Tools and applications, 1-14, 2009 | 1 | 2009 |
| Use of AEX-HPLC-ESI-MS for 13C-Labeling Based Metabolic Flux Analysis in Saccharomyces cerevisiae and Penicillium RJ Kleijn, WM van Gulik, JJ Heijnen The Metabolic Pathway Engineering Handbook: Tools and Applications 2, 2009 | | 2009 |
| Relation between central metabolism and β-lactam production in Penicillium chrysogenum: a metabolomics study L Wu, WM Van Gulik, RJ Kleijn, U Nasution, RM Seifar, WA van Winden, ... | | 2007 |
