Targeting fibrosis: Mechanisms and clinical trials M Zhao, L Wang, M Wang, S Zhou, Y Lu, H Cui, AC Racanelli, L Zhang, ... Signal transduction and targeted therapy 7 (1), 206, 2022 | 152 | 2022 |
Liver fibrosis: therapeutic targets and advances in drug therapy Z Tan, H Sun, T Xue, C Gan, H Liu, Y Xie, Y Yao, T Ye Frontiers in cell and developmental biology 9, 730176, 2021 | 132 | 2021 |
Betulinic acid impairs metastasis and reduces immunosuppressive cells in breast cancer models AQ Zeng, Y Yu, YQ Yao, FF Yang, M Liao, LJ Song, YL Li, Y Yu, YJ Li, ... Oncotarget 9 (3), 3794, 2018 | 65 | 2018 |
Discovery of the first potent proteolysis targeting chimera (PROTAC) degrader of indoleamine 2, 3-dioxygenase 1 M Hu, W Zhou, Y Wang, D Yao, T Ye, Y Yao, B Chen, G Liu, X Yang, ... Acta Pharmaceutica Sinica B 10 (10), 1943-1953, 2020 | 56 | 2020 |
Punica granatum (pomegranate) peel extract exerts potent antitumor and anti-metastasis activity in thyroid cancer Y Li, T Ye, F Yang, M Hu, L Liang, H He, Z Li, A Zeng, Y Li, Y Yao, Y Xie, ... RSC advances 6 (87), 84523-84535, 2016 | 47 | 2016 |
CA II, a potential biomarker by proteomic analysis, exerts significant inhibitory effect on the growth of colorectal cancer cells R Zhou, W Huang, Y Yao, Y Wang, Z Li, B Shao, J Zhong, M Tang, ... International journal of oncology 43 (2), 611-621, 2013 | 42 | 2013 |
Therapeutic potential of an anti-HER2 single chain antibody–DM1 conjugates for the treatment of HER2-positive cancer H Zhang, Y Wang, Y Wu, X Jiang, Y Tao, Y Yao, Y Peng, X Chen, Y Fu, ... Signal transduction and targeted therapy 2 (1), 1-11, 2017 | 41 | 2017 |
Piperlongumine induces apoptosis in human melanoma cells via reactive oxygen species mediated mitochondria disruption X Song, T Gao, Q Lei, L Zhang, Y Yao, J Xiong Nutrition and cancer 70 (3), 502-511, 2018 | 40 | 2018 |
Synthesis, characterization and targeting chemotherapy for ovarian cancer of trastuzumab-SN-38 conjugates Y Yao, L Yu, X Su, Y Wang, W Li, Y Wu, X Cheng, H Zhang, X Wei, ... Journal of Controlled Release 220, 5-17, 2015 | 40 | 2015 |
The effect of miR‐7 on behavior and global protein expression in glioma cell lines ZJ Lu, SY Liu, YQ Yao, YJ Zhou, S Zhang, L Dai, HW Tian, Y Zhou, ... Electrophoresis 32 (24), 3612-3620, 2011 | 38 | 2011 |
The role of natural products in the prevention and treatment of pulmonary fibrosis: A review L Wang, S Li, Y Yao, W Yin, T Ye Food & function 12 (3), 990-1007, 2021 | 34 | 2021 |
Isoliquiritigenin inhibits the growth of multiple myeloma via blocking IL-6 signaling X Chen, Y Wu, Y Jiang, Y Zhou, Y Wang, Y Yao, C Yi, L Gou, J Yang Journal of molecular medicine 90, 1311-1319, 2012 | 34 | 2012 |
Design, synthesis and biological evaluation of a novel tubulin inhibitor 7a3 targeting the colchicine binding site Q Lai, Y Wang, R Wang, W Lai, L Tang, Y Tao, Y Liu, R Zhang, L Huang, ... European Journal of Medicinal Chemistry 156, 162-179, 2018 | 33 | 2018 |
Hinokiflavone induces apoptosis in melanoma cells through the ROS-mitochondrial apoptotic pathway and impairs cell migration and invasion S Yang, Y Zhang, Y Luo, B Xu, Y Yao, Y Deng, F Yang, T Ye, G Wang, ... Biomedicine & Pharmacotherapy 103, 101-110, 2018 | 33 | 2018 |
High ECT2 expression is an independent prognostic factor for poor overall survival and recurrence-free survival in non-small cell lung adenocarcinoma S Zhou, P Wang, X Su, J Chen, H Chen, H Yang, A Fang, L Xie, Y Yao, ... PloS one 12 (10), e0187356, 2017 | 33 | 2017 |
Comparative RNA‐Seq transcriptome analysis on silica induced pulmonary inflammation and fibrosis in mice silicosis model J Chen, Y Yao, X Su, Y Shi, X Song, L Xie, J You, L Tian, L Yang, A Fang, ... Journal of Applied Toxicology 38 (5), 773-782, 2018 | 32 | 2018 |
Promiximab-duocarmycin, a new CD56 antibody-drug conjugates, is highly efficacious in small cell lung cancer xenograft models L Yu, Y Lu, Y Yao, Y Liu, Y Wang, Q Lai, R Zhang, W Li, R Wang, Y Fu, ... Oncotarget 9 (4), 5197, 2018 | 31 | 2018 |
Facile synthesis of functionalized spiropyrrolizidine oxindoles via a three-component tandem cycloaddition reaction YM Xie, YQ Yao, HB Sun, TT Yan, J Liu, TR Kang Molecules 16 (10), 8745-8757, 2011 | 31 | 2011 |
Cryptotanshinone reverses the epithelial‐mesenchymal transformation process and attenuates bleomycin‐induced pulmonary fibrosis Q Zhang, C Gan, H Liu, L Wang, Y Li, Z Tan, J You, Y Yao, Y Xie, W Yin, ... Phytotherapy Research 34 (10), 2685-2696, 2020 | 30 | 2020 |
Eradication of growth of HER2-positive ovarian cancer with trastuzumab-DM1, an antibody-cytotoxic drug conjugate in mouse xenograft model L Yu, Y Wang, Y Yao, W Li, Q Lai, J Li, Y Zhou, T Kang, Y Xie, Y Wu, ... International Journal of Gynecologic Cancer 24 (7), 2014 | 30 | 2014 |