TRAF6 promotes atypical ubiquitination of mutant DJ-1 and alpha-synuclein and is localized to Lewy bodies in sporadic Parkinson's disease brains S Zucchelli, M Codrich, F Marcuzzi, M Pinto, S Vilotti, M Biagioli, I Ferrer, ... Human molecular genetics 19 (19), 3759-3770, 2010 | 113 | 2010 |
Tumor necrosis factor receptor-associated factor 6 (TRAF6) associates with huntingtin protein and promotes its atypical ubiquitination to enhance aggregate formation S Zucchelli, F Marcuzzi, M Codrich, E Agostoni, S Vilotti, M Biagioli, ... Journal of Biological Chemistry 286 (28), 25108-25117, 2011 | 76 | 2011 |
Parkinson's disease DJ-1 L166P alters rRNA biogenesis by exclusion of TTRAP from the nucleolus and sequestration into cytoplasmic aggregates via TRAF6 S Vilotti, M Codrich, M Dal Ferro, M Pinto, I Ferrer, L Collavin, S Gustincich, ... PloS one 7 (4), e35051, 2012 | 59 | 2012 |
Hemoglobin is present as a canonical α2β2 tetramer in dopaminergic neurons R Russo, S Zucchelli, M Codrich, F Marcuzzi, C Verde, S Gustincich Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1834 (9), 1939-1943, 2013 | 54 | 2013 |
Neuronal hemoglobin affects dopaminergic cells’ response to stress M Codrich, M Bertuzzi, R Russo, M Francescatto, S Espinoza, L Zentilin, ... Cell death & disease 8 (1), e2538-e2538, 2018 | 40 | 2018 |
Inhibition of APE1-endonuclease activity affects cell metabolism in colon cancer cells via a p53-dependent pathway M Codrich, M Comelli, MC Malfatti, C Mio, D Ayyildiz, C Zhang, MR Kelley, ... DNA repair 82, 102675, 2019 | 36 | 2019 |
Integrated multi-omics analyses on patient-derived CRC organoids highlight altered molecular pathways in colorectal cancer progression involving PTEN M Codrich, E Dalla, C Mio, G Antoniali, MC Malfatti, S Marzinotto, ... Journal of Experimental & Clinical Cancer Research 40, 1-17, 2021 | 35 | 2021 |
Coping with RNA damage with a focus on APE1, a BER enzyme at the crossroad between DNA damage repair and RNA processing/decay MC Malfatti, G Antoniali, M Codrich, G Tell DNA repair 104, 103133, 2021 | 26 | 2021 |
New perspectives in cancer biology from a study of canonical and non-canonical functions of base excision repair proteins with a focus on early steps MC Malfatti, G Antoniali, M Codrich, S Burra, G Mangiapane, E Dalla, ... Mutagenesis 35 (1), 129-149, 2020 | 25 | 2020 |
Design and advanced characterization of quercetin-loaded nano-liposomes prepared by high-pressure homogenization S Melchior, M Codrich, A Gorassini, D Mehn, J Ponti, G Verardo, G Tell, ... Food Chemistry 428, 136680, 2023 | 15 | 2023 |
Role of condensates in modulating DNA repair pathways and its implication for chemoresistance G Dall’Agnese, A Dall’Agnese, SF Banani, M Codrich, MC Malfatti, ... Journal of Biological Chemistry 299 (6), 2023 | 10 | 2023 |
Combining deep phenotyping of serum proteomics and clinical data via machine learning for COVID-19 biomarker discovery AP Beltrami, M De Martino, E Dalla, MC Malfatti, F Caponnetto, M Codrich, ... International Journal of Molecular Sciences 23 (16), 9161, 2022 | 10 | 2022 |
Compensatory changes in degenerating spinal motoneurons sustain functional sparing in the SOD1‐G93A mouse model of amyotrophic lateral sclerosis E Giusto, M Codrich, G de Leo, V Francardo, M Coradazzi, R Parenti, ... Journal of Comparative Neurology 528 (2), 231-243, 2020 | 10 | 2020 |
APE1 interacts with the nuclear exosome complex protein MTR4 and is involved in cisplatin‐and 5‐fluorouracil‐induced RNA damage response M Codrich, M Degrassi, MC Malfatti, G Antoniali, A Gorassini, D Ayyildiz, ... The FEBS Journal 290 (7), 1740-1764, 2023 | 4 | 2023 |
The E3 ubiquitin ligase TRAF6 interacts with the cellular prion protein and modulates its solubility and recruitment to cytoplasmic p62/SQSTM1-positive Aggresome-like structures L Masperone, M Codrich, F Persichetti, S Gustincich, S Zucchelli, ... Molecular Neurobiology 59 (3), 1577-1588, 2022 | 4 | 2022 |
AUF1 Recognizes 8-Oxo-Guanosine Embedded in DNA and Stimulates APE1 Endoribonuclease Activity MC Malfatti, M Codrich, E Dalla, C D'Ambrosio, F Storici, A Scaloni, G Tell Antioxidants & Redox Signaling 39 (7-9), 411-431, 2023 | 3 | 2023 |
Neuronal haemoglobin induces loss of dopaminergic neurons in mouse Substantia nigra, cognitive deficits and cleavage of endogenous α-synuclein C Santulli, C Bon, E De Cecco, M Codrich, J Narkiewicz, P Parisse, ... Cell Death & Disease 13 (12), 1048, 2022 | 2 | 2022 |
Neuronal hemoglobin induces loss of dopaminergic neurons in mouse Substantia nigra, cognitive deficits and cleavage of endogenous α-synuclein S Chiara, B Carlotta, DC Elena, C Marta, N Joanna, P Pietro, P Fabio, ... | 1 | 2021 |
Expression of APE1 endonuclease in primarily cultured aortic valve interstitial cells undergoing spontaneous senescence. A Bonetti, G Antoniali, MC Malfatti, M Codrich, M Contin, G Tell, F Ortolani Italian Journal of Anatomy & Embryology/Archivio Italiano di Anatomia Ed …, 2023 | | 2023 |
Neuronal hemoglobin induces α-synuclein cleavage and loss of dopaminergic neurons S Chiara, B Carlotta, DC Elena, C Marta, N Joanna, P Pietro, P Fabio, ... bioRxiv, 2021.10. 13.464204, 2021 | | 2021 |