HSP90 at the hub of protein homeostasis: emerging mechanistic insights M Taipale, DF Jarosz, S Lindquist Nature reviews Molecular cell biology 11 (7), 515-528, 2010 | 1999 | 2010 |
DNA-binding specificities of human transcription factors A Jolma, J Yan, T Whitington, J Toivonen, KR Nitta, P Rastas, ... Cell 152 (1), 327-339, 2013 | 1376 | 2013 |
Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition M Taipale, I Krykbaeva, M Koeva, C Kayatekin, KD Westover, GI Karras, ... Cell 150 (5), 987-1001, 2012 | 900 | 2012 |
Genome‐wide analysis of ETS‐family DNA‐binding in vitro and in vivo GH Wei, G Badis, MF Berger, T Kivioja, K Palin, M Enge, M Bonke, ... The EMBO journal 29 (13), 2147-2160, 2010 | 664 | 2010 |
Widespread macromolecular interaction perturbations in human genetic disorders N Sahni, S Yi, M Taipale, JIF Bass, J Coulombe-Huntington, F Yang, ... Cell 161 (3), 647-660, 2015 | 572 | 2015 |
A candidate gene for developmental dyslexia encodes a nuclear tetratricopeptide repeat domain protein dynamically regulated in brain M Taipale, N Kaminen, J Nopola-Hemmi, T Haltia, B Myllyluoma, ... Proceedings of the National Academy of Sciences 100 (20), 11553-11558, 2003 | 543 | 2003 |
Multiplexed massively parallel SELEX for characterization of human transcription factor binding specificities A Jolma, T Kivioja, J Toivonen, L Cheng, G Wei, M Enge, M Taipale, ... Genome research 20 (6), 861-873, 2010 | 530 | 2010 |
The Axon Guidance Receptor Gene ROBO1 Is a Candidate Gene for Developmental Dyslexia K Hannula-Jouppi, N Kaminen-Ahola, M Taipale, R Eklund, ... PLoS genetics 1 (4), e50, 2005 | 475 | 2005 |
Nuclear pore components are involved in the transcriptional regulation of dosage compensation in Drosophila S Mendjan, M Taipale, J Kind, H Holz, P Gebhardt, M Schelder, ... Molecular cell 21 (6), 811-823, 2006 | 463 | 2006 |
A quantitative chaperone interaction network reveals the architecture of cellular protein homeostasis pathways M Taipale, G Tucker, J Peng, I Krykbaeva, ZY Lin, B Larsen, H Choi, ... Cell 158 (2), 434-448, 2014 | 434 | 2014 |
Widespread regulation of translation by elongation pausing in heat shock R Shalgi, JA Hurt, I Krykbaeva, M Taipale, S Lindquist, CB Burge Molecular cell 49 (3), 439-452, 2013 | 377 | 2013 |
hMOF histone acetyltransferase is required for histone H4 lysine 16 acetylation in mammalian cells M Taipale, S Rea, K Richter, A Vilar, P Lichter, A Imhof, A Akhtar Molecular and cellular biology, 2005 | 361 | 2005 |
Mapping differential interactomes by affinity purification coupled with data-independent mass spectrometry acquisition JP Lambert, G Ivosev, AL Couzens, B Larsen, M Taipale, ZY Lin, Q Zhong, ... Nature methods 10 (12), 1239-1245, 2013 | 335 | 2013 |
A dominant gene for developmental dyslexia on chromosome 3 J Nopola-Hemmi, B Myllyluoma, T Haltia, M Taipale, V Ollikainen, ... Journal of medical genetics 38 (10), 658-664, 2001 | 238 | 2001 |
The mammalian-membrane two-hybrid assay (MaMTH) for probing membrane-protein interactions in human cells J Petschnigg, B Groisman, M Kotlyar, M Taipale, Y Zheng, CF Kurat, ... Nature methods 11 (5), 585-592, 2014 | 201 | 2014 |
The histone acetyltransferase hMOF is frequently downregulated in primary breast carcinoma and medulloblastoma and constitutes a biomarker for clinical outcome in medulloblastoma S Pfister, S Rea, M Taipale, F Mendrzyk, B Straub, C Ittrich, O Thuerigen, ... International journal of cancer 122 (6), 1207-1213, 2008 | 192 | 2008 |
Protein homeostasis and the phenotypic manifestation of genetic diversity: principles and mechanisms DF Jarosz, M Taipale, S Lindquist Annual review of genetics 44, 189-216, 2010 | 191 | 2010 |
Germline HAVCR2 mutations altering TIM-3 characterize subcutaneous panniculitis-like T cell lymphomas with hemophagocytic lymphohistiocytic syndrome T Gayden, FE Sepulveda, DA Khuong-Quang, J Pratt, ET Valera, ... Nature genetics 50 (12), 1650-1657, 2018 | 184 | 2018 |
Two translocations of chromosome 15q associated with dyslexia J Nopola-Hemmi, M Taipale, T Haltia, AE Lehesjoki, A Voutilainen, J Kere Journal of Medical Genetics 37 (10), 771-775, 2000 | 162 | 2000 |
An efficient KRAB domain for CRISPRi applications in human cells N Alerasool, D Segal, H Lee, M Taipale Nature methods 17 (11), 1093-1096, 2020 | 155 | 2020 |