Synergism of TNF-α and IFN-γ triggers inflammatory cell death, tissue damage, and mortality in SARS-CoV-2 infection and cytokine shock syndromes R Karki, BR Sharma, S Tuladhar, EP Williams, L Zalduondo, P Samir, ... Cell 184 (1), 149-168. e17, 2021 | 1194 | 2021 |
ADAR1 restricts ZBP1-mediated immune response and PANoptosis to promote tumorigenesis R Karki, B Sundaram, BR Sharma, SJ Lee, RKS Malireddi, LN Nguyen, ... Cell reports 37 (3), 2021 | 193 | 2021 |
Malaria parasite-synthesized heme is essential in the mosquito and liver stages and complements host heme in the blood stages of infection VA Nagaraj, B Sundaram, NM Varadarajan, PA Subramani, DM Kalappa, ... PLoS pathogens 9 (8), e1003522, 2013 | 166 | 2013 |
Inflammatory cell death, PANoptosis, mediated by cytokines in diverse cancer lineages inhibits tumor growth RK Malireddi, R Karki, B Sundaram, B Kancharana, SJ Lee, P Samir, ... Immunohorizons 5 (7), 568-580, 2021 | 107 | 2021 |
Advances in understanding activation and function of the NLRC4 inflammasome B Sundaram, TD Kanneganti International journal of molecular sciences 22 (3), 1048, 2021 | 87 | 2021 |
NLRP12-PANoptosome activates PANoptosis and pathology in response to heme and PAMPs B Sundaram, N Pandian, R Mall, Y Wang, R Sarkar, HJ Kim, ... Cell 186 (13), 2783-2801. e20, 2023 | 70 | 2023 |
Renal control of disease tolerance to malaria S Ramos, AR Carlos, B Sundaram, V Jeney, A Ribeiro, R Gozzelino, ... Proceedings of the National Academy of Sciences 116 (12), 5681-5686, 2019 | 67 | 2019 |
Deletions in the cytoplasmic domain of iRhom1 and iRhom2 promote shedding of the TNF receptor by the protease ADAM17 SK Maney, DR McIlwain, R Polz, AA Pandyra, B Sundaram, D Wolff, ... Science signaling 8 (401), ra109-ra109, 2015 | 67 | 2015 |
Single cell analysis of PANoptosome cell death complexes through an expansion microscopy method Y Wang, N Pandian, JH Han, B Sundaram, SJ Lee, R Karki, CS Guy, ... Cellular and Molecular Life Sciences 79 (10), 531, 2022 | 26 | 2022 |
iRhom2 inhibits bile duct obstruction–induced liver fibrosis B Sundaram, K Behnke, A Belancic, MA Al-Salihi, Y Thabet, R Polz, ... Science Signaling 12 (605), eaax1194, 2019 | 22 | 2019 |
B cell‐mediated maintenance of cluster of differentiation 169–positive cells is critical for liver regeneration K Behnke, Y Zhuang, HC Xu, B Sundaram, M Reich, PV Shinde, J Huang, ... Hepatology 68 (6), 2348-2361, 2018 | 22 | 2018 |
Inflammatory cell death, PANoptosis, mediated by cytokines in diverse cancer lineages inhibits tumor growth. Immunohorizons 5, 568–580 RKS Malireddi, R Karki, B Sundaram, B Kancharana, S Lee, P Samir, ... Epub 2021/07/23. doi: 10.4049/immunohorizons. 2100059, 2021 | 20 | 2021 |
Fragile X mental retardation protein protects against tumour necrosis factor-mediated cell death and liver injury Y Zhuang, HC Xu, PV Shinde, J Warfsmann, J Vasilevska, B Sundaram, ... Gut 69 (1), 133-145, 2020 | 17 | 2020 |
BAFF attenuates immunosuppressive monocytes in the melanoma tumor microenvironment W Liu, P Stachura, HC Xu, R Váraljai, P Shinde, NU Ganesh, M Mack, ... Cancer research 82 (2), 264-277, 2022 | 10 | 2022 |
Cholestasis induced liver pathology results in dysfunctional immune responses after arenavirus infection E Lang, VI Pozdeev, PV Shinde, HC Xu, B Sundaram, Y Zhuang, ... Scientific reports 8 (1), 12179, 2018 | 8 | 2018 |
The NLR family of innate immune and cell death sensors B Sundaram, RE Tweedell, SP Kumar, TD Kanneganti Immunity 57 (4), 674-699, 2024 | 7 | 2024 |
The transcription factor IRF9 promotes colorectal cancer via modulating the IL-6/STAT3 signaling axis BR Sharma, R Karki, B Sundaram, Y Wang, P Vogel, TD Kanneganti Cancers 14 (4), 919, 2022 | 7 | 2022 |
NLRC4 deficiency leads to enhanced phosphorylation of MLKL and necroptosis B Sundaram, R Karki, TD Kanneganti Immunohorizons 6 (3), 243-252, 2022 | 5 | 2022 |
Plasmodium berghei glycine cleavage system T-protein is non-essential for parasite survival in vertebrate and invertebrate hosts NM Varadarajan, B Sundaram, PA Subramani, DM Kalappa, SK Ghosh, ... Molecular and Biochemical Parasitology 197 (1-2), 50-55, 2014 | 3 | 2014 |
NLRC5 senses NAD+ depletion, forming a PANoptosome and driving PANoptosis and inflammation B Sundaram, N Pandian, HJ Kim, HM Abdelaal, R Mall, O Indari, R Sarkar, ... Cell, 2024 | 1 | 2024 |