| Fibroblast-derived CXCL12 promotes breast cancer metastasis by facilitating tumor cell intravasation DK Ahirwar, MW Nasser, MM Ouseph, M Elbaz, MC Cuitiño, RD Kladney, ... Oncogene 37 (32), 4428-4442, 2018 | 117 | 2018 |
| Modeling human cancer-induced cachexia EE Talbert, MC Cuitiño, KJ Ladner, PV Rajasekerea, M Siebert, R Shakya, ... Cell reports 28 (6), 1612-1622. e4, 2019 | 114 | 2019 |
| E2f8 mediates tumor suppression in postnatal liver development LN Kent, JB Rakijas, SK Pandit, B Westendorp, HZ Chen, JT Huntington, ... The Journal of clinical investigation 126 (8), 2955-2969, 2016 | 96 | 2016 |
| Cyclin F controls cell-cycle transcriptional outputs by directing the degradation of the three activator E2Fs L Clijsters, C Hoencamp, JJA Calis, A Marzio, SM Handgraaf, MC Cuitino, ... Molecular cell 74 (6), 1264-1277. e7, 2019 | 77 | 2019 |
| Stromal PDGFR-α activation enhances matrix stiffness, impedes mammary ductal development, and accelerates tumor growth AM Hammer, GM Sizemore, VC Shukla, A Avendano, ST Sizemore, ... Neoplasia 19 (6), 496-508, 2017 | 67 | 2017 |
| Two distinct E2F transcriptional modules drive cell cycles and differentiation MC Cuitiño, T Pécot, D Sun, R Kladney, T Okano-Uchida, N Shinde, ... Cell reports 27 (12), 3547-3560. e5, 2019 | 61 | 2019 |
| Genetic ablation of Smoothened in pancreatic fibroblasts increases acinar–ductal metaplasia X Liu, JR Pitarresi, MC Cuitiño, RD Kladney, SA Woelke, GM Sizemore, ... Genes & development 30 (17), 1943-1955, 2016 | 57 | 2016 |
| Abrupt involution induces inflammation, estrogenic signaling, and hyperplasia linking lack of breastfeeding with increased risk of breast cancer MM Basree, N Shinde, C Koivisto, M Cuitino, R Kladney, J Zhang, ... Breast Cancer Research 21, 1-18, 2019 | 38 | 2019 |
| Stromal platelet–derived growth factor receptor-β signaling promotes breast cancer metastasis in the brain KA Thies, AM Hammer, BE Hildreth III, SA Steck, JM Spehar, RD Kladney, ... Cancer research 81 (3), 606-618, 2021 | 36 | 2021 |
| Disruption of stromal hedgehog signaling initiates RNF5-mediated proteasomal degradation of PTEN and accelerates pancreatic tumor growth JR Pitarresi, X Liu, A Avendano, KA Thies, GM Sizemore, AM Hammer, ... Life science alliance 1 (5), 2018 | 35 | 2018 |
| Stromal ETS2 regulates chemokine production and immune cell recruitment during acinar-to-ductal metaplasia JR Pitarresi, X Liu, SM Sharma, MC Cuitiño, RD Kladney, TA Mace, ... Neoplasia 18 (9), 541-552, 2016 | 35 | 2016 |
| Noncatalytic PTEN missense mutation predisposes to organ-selective cancer development in vivo E Caserta, O Egriboz, H Wang, C Martin, C Koivisto, T Pecót, RD Kladney, ... Genes & development 29 (16), 1707-1720, 2015 | 31 | 2015 |
| Protein kinase C Beta in the tumor microenvironment promotes mammary tumorigenesis JA Wallace, JR Pitarresi, N Sharma, M Palettas, MC Cuitiño, ST Sizemore, ... Frontiers in oncology 4, 87, 2014 | 30 | 2014 |
| STAT3 in tumor fibroblasts promotes an immunosuppressive microenvironment in pancreatic cancer JE Lefler, CB MarElia-Bennett, KA Thies, BE Hildreth, SM Sharma, ... Life science alliance 5 (11), 2022 | 24 | 2022 |
| Endoreduplication of the mouse genome in the absence of ORC1 T Okano-Uchida, LN Kent, MM Ouseph, B McCarty, JJ Frank, R Kladney, ... Genes & development 32 (13-14), 978-990, 2018 | 23 | 2018 |
| Stromal PTEN determines mammary epithelial response to radiotherapy GM Sizemore, S Balakrishnan, KA Thies, AM Hammer, ST Sizemore, ... Nature communications 9 (1), 2783, 2018 | 20 | 2018 |
| Generation of a pancreatic cancer model using a Pdx1-Flp recombinase knock-in allele J Wu, X Liu, SG Nayak, JR Pitarresi, MC Cuitiño, L Yu, BE Hildreth III, ... PloS one 12 (9), e0184984, 2017 | 20 | 2017 |
| Failure to target RANKL signaling through p38‐MAPK results in defective osteoclastogenesis in the microphthalmia cloudy‐eyed mutant HA Carey, A Bronisz, J Cabrera, BE Hildreth III, M Cuitiño, QI Fu, A Ahmad, ... Journal of cellular physiology 231 (3), 630-640, 2016 | 11 | 2016 |
| Deep learning tools and modeling to estimate the temporal expression of cell cycle proteins from 2D still images T Pécot, MC Cuitiño, RH Johnson, C Timmers, G Leone PLOS Computational Biology 18 (3), e1009949, 2022 | 10* | 2022 |
| Lack of prognostic significance of angiogenesis in canine melanocytic tumours MC Cuitino, AR Massone, JR Idiart Journal of Comparative Pathology 147 (2-3), 147-152, 2012 | 8 | 2012 |
