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Kushal Saha
Kushal Saha
Postdoctoral Research Fellow, Harvard Medical School
在 bwh.harvard.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Matrix metalloproteinase MMP-12 promotes macrophage transmigration across intestinal epithelial tight junctions and increases severity of experimental colitis
M Nighot, AS Ganapathy, K Saha, E Suchanec, EF Castillo, A Gregory, ...
Journal of Crohn's and Colitis 15 (10), 1751-1765, 2021
662021
AP2M1 mediates autophagy-induced CLDN2 (claudin 2) degradation through endocytosis and interaction with LC3 and reduces intestinal epithelial tight junction permeability
TMPN Ashwinkumar Subramenium Ganapathy, Kushal Saha, Eric Suchanec, Ayush ...
Autophagy 17 (12), 2021
57*2021
Autophagy reduces the degradation and promotes membrane localization of occludin to enhance the intestinal epithelial tight junction barrier against paracellular macromolecule flux
K Saha, A Subramenium Ganapathy, A Wang, N Michael Morris, ...
Journal of Crohn's and Colitis 17 (3), 433-449, 2023
352023
Long-Term use of proton pump inhibitors disrupts intestinal tight junction barrier and exaggerates experimental colitis
M Nighot, PL Liao, N Morris, D McCarthy, V Dharmaprakash, I Ullah Khan, ...
Journal of Crohn's and Colitis 17 (4), 565-579, 2023
202023
Alpha-tocopherylquinone differentially modulates claudins to enhance intestinal epithelial tight junction barrier via AhR and Nrf2 pathways
AS Ganapathy, K Saha, A Wang, P Arumugam, V Dharmaprakash, ...
Cell reports 42 (7), 2023
132023
Alpha-tocopherylquinone-mediated activation of the Aryl Hydrocarbon Receptor regulates the production of inflammation-inducing cytokines and ameliorates intestinal inflammation
K Saha, AS Ganapathy, A Wang, P Arumugam, NM Morris, L Harris, ...
Mucosal immunology 16 (6), 826-842, 2023
22023
Autophagy Increases Occludin Levels to Enhance Intestinal Paracellular Tight Junction Barrier
K Saha, AS Ganapathy, A Wang, NM Morris, E Suchanec, G Yochum, ...
bioRxiv, 2022.04. 11.487876, 2022
12022
Tight junction regulation, intestinal permeability, and mucosal immunity in gastrointestinal health and disease
K Saha, Y Zhou, JR Turner
Current Opinion in Gastroenterology 41 (1), 46-53, 2025
2025
Regional Heterogeneity in Intestinal Epithelial Barrier Permeability and Mesenteric Perfusion After Thoracic Spinal Cord Injury
JB Radler, AR McBride, K Saha, P Nighot, GM Holmes
Digestive Diseases and Sciences 69 (9), 3236-3248, 2024
2024
107 AUTOPHAGY AMELIORATES ER STRESS-MEDIATED INTESTINAL TIGHT JUNCTION BARRIER DYSFUNCTION
P Arumugam, AS Ganapathy, K Saha, P Nighot
Gastroenterology 166 (5), S-29-S-30, 2024
2024
Intestinal Epithelial Tight Junction Barrier Regulation by Novel Pathways
P Arumugam, K Saha, P Nighot
Inflammatory Bowel Diseases, 2024
2024
Assessing novel mechanisms to understand the dynamics of the Intestinal milieu in Inflammatory Bowel Diseases.
K Saha
2024
Intestinal epithelium-specific deletion of the Aryl hydrocarbon Receptor (AhR) reduces intestinal Tight Junction permeability thereby hindering homeostatic antigen sampling and …
K Saha, AS Ganapathy, P Arumugam, A Wang, L Harris, G Yochum, ...
JOURNAL OF CROHNS & COLITIS 18, I227-I227, 2024
2024
DOP83 Intestinal epithelium-specific deletion of the Aryl hydrocarbon Receptor (AhR) reduces intestinal Tight Junction permeability thereby hindering homeostatic antigen …
K Saha, AS Ganapathy, P Arumugam, A Wang, L Harris, G Yochum, ...
Journal of Crohn's and Colitis 18 (Supplement_1), i229-i229, 2024
2024
955 ALPHA-TOCOPHERYLQUINONE (TQ) REDUCES INTESTINAL INFLAMMATION BY INHIBITING NFkB AND STAT3 SIGNALING IN AN ARYL HYDROCARBON RECEPTOR (AHR) DEPENDENT MECHANISM
K Saha, AS Ganapathy, A Wang, NM Morris, L Harris, GS Yochum, ...
Gastroenterology 164 (6), S-209-S-210, 2023
2023
282 ALPHA-TOCOPHERYLQUINONE ACTIVATE AHR/NRF2 PATHWAY AND ENHANCES INTESTINAL EPITHELIAL TIGHT JUNCTION BARRIER VIA DIFFERENTIAL MODULATION OF CLAUDINS
AS Ganapathy, K Saha, A Wang, V Dharmaprakash, GS Yochum, ...
Gastroenterology 164 (6), S-53, 2023
2023
664 INTESTINAL EPITHELIA-SPECIFIC DELETION OF ARYL HYDROCARBON RECEPTOR (AHR) REDUCES PARACELLULAR TIGHT JUNCTION PERMEABILITY AND HINDERS IMMUNOGENIC TOLERANCE
A Venkatesh, K Saha, AS Ganapathy, A Wang, NM Morris, MT Nighot, ...
Gastroenterology 164 (6), S-129, 2023
2023
DOP68 Autophagy induction in the intestinal epithelium protects against inflammation-induced barrier loss in vivo.
K Saha, AS Ganapathy, A Wang, N Morris, G Yochum, W Koltun, W Ding, ...
Journal of Crohn's and Colitis 17 (Supplement_1), i144-i145, 2023
2023
596: AP2M1 AND LC3 LIPIDATION GUIDES CLAUDIN-2 INTO AUTOLYSOSOME
AS Ganapathy, K Saha, A Wang, MT Nighot, TY Ma, P Nighot
Gastroenterology 162 (7), S-149, 2022
2022
352: PPI ADMINISTRATION INDUCED COLONIC TIGHT JUNCTION BARRIER DYSFUNCTION IS ASSOCIATED WITH INCREASE IN PH, MLCK AND ENETROCOCCUS FECALIS.
NM Morris, K Saha, AS Ganapathy, PK Nighot, K Clarke, TY Ma, ...
Gastroenterology 162 (7), S-76, 2022
2022
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