CRISPR/Cas9 cleavage of viral DNA efficiently suppresses hepatitis B virus V Ramanan, A Shlomai, DBT Cox, RE Schwartz, E Michailidis, A Bhatta, ... Scientific reports 5 (1), 10833, 2015 | 326 | 2015 |
Modeling host interactions with hepatitis B virus using primary and induced pluripotent stem cell-derived hepatocellular systems A Shlomai, RE Schwartz, V Ramanan, A Bhatta, YP de Jong, SN Bhatia, ... Proceedings of the National Academy of Sciences 111 (33), 12193-12198, 2014 | 270 | 2014 |
Development of light‐activated CRISPR using guide RNAs with photocleavable protectors PK Jain, V Ramanan, AG Schepers, NS Dalvie, A Panda, HE Fleming, ... Angewandte Chemie International Edition 55 (40), 12440-12444, 2016 | 181 | 2016 |
In situ expansion of engineered human liver tissue in a mouse model of chronic liver disease KR Stevens, MA Scull, V Ramanan, CL Fortin, RR Chaturvedi, KA Knouse, ... Science translational medicine 9 (399), eaah5505, 2017 | 171 | 2017 |
Micropatterned coculture of primary human hepatocytes and supportive cells for the study of hepatotropic pathogens S March, V Ramanan, K Trehan, S Ng, A Galstian, N Gural, MA Scull, ... Nature protocols 10 (12), 2027-2053, 2015 | 168 | 2015 |
Systems biology and physical biology of clathrin-mediated endocytosis V Ramanan, NJ Agrawal, J Liu, S Engles, R Toy, R Radhakrishnan Integrative Biology 3 (8), 803-815, 2011 | 80 | 2011 |
A robust cell culture system supporting the complete life cycle of hepatitis B virus E Michailidis, J Pabon, K Xiang, P Park, V Ramanan, HH Hoffmann, ... Scientific reports 7 (1), 16616, 2017 | 73 | 2017 |
Photocleavable side groups to spatially alter hydrogel properties and cellular interactions VV Ramanan, JS Katz, M Guvendiren, ER Cohen, RA Marklein, ... Journal of Materials Chemistry 20 (40), 8920-8926, 2010 | 46 | 2010 |
Hepatitis B virus induces RNR-R2 expression via DNA damage response activation I Ricardo-Lax, V Ramanan, E Michailidis, T Shamia, N Reuven, CM Rice, ... Journal of hepatology 63 (4), 789-796, 2015 | 35 | 2015 |
New methods in tissue engineering: improved models for viral infection V Ramanan, MA Scull, TP Sheahan, CM Rice, SN Bhatia Annual review of virology 1 (1), 475-499, 2014 | 29 | 2014 |
Mesoscale simulations of curvature-inducing protein partitioning on lipid bilayer membranes in the presence of mean curvature fields J Liu, R Tourdot, V Ramanan, NJ Agrawal, R Radhakrishanan Molecular physics 110 (11-12), 1127-1137, 2012 | 29 | 2012 |
Nanofiber–nanorod composites exhibiting light-induced reversible lower critical solution temperature transitions VV Ramanan, KC Hribar, JS Katz, JA Burdick Nanotechnology 22 (49), 494009, 2011 | 25 | 2011 |
Viral genome imaging of hepatitis C virus to probe heterogeneous viral infection and responses to antiviral therapies V Ramanan, K Trehan, ML Ong, JM Luna, HH Hoffmann, C Espiritu, ... Virology 494, 236-247, 2016 | 19 | 2016 |
Delivery, use and therapeutic applications of the crispr-cas systems and compositions for hbv and viral diseases and disorders S Bhatia, C Rice, F Zhang, DBT Cox, V Ramanan, R Schwartz, A Shlomai | 11 | 2015 |
Delivery, use and therapeutic applications of the crispr-cas systems and compositions for hbv and viral diseases and disorders S Bhatia, C Rice, F Zhang, DBT Cox, V Ramanan, R Schwartz, A Shlomai US Patent App. 17/002,262, 2020 | 9 | 2020 |
TARGETING VIRAL DNA WITH CRISPR/Cas9 ROBUSTLY SUPPRESSES HEPATITIS B VIRUS A Shlomai, V Ramanan, DB Cox, RE Schwartz, E Michailidis, A Bhatta, ... JOURNAL OF HEPATOLOGY 62, S519-S519, 2015 | 2 | 2015 |
Genomic profiling and perturbation of Hepatitis B virus infection V Ramanan Massachusetts Institute of Technology, 2016 | | 2016 |
P0545: Targeting viral DNA with CRISPR/Cas9 robustly suppresses hepatitis B virus V Ramanan, DB Cox, RE Schwartz, E Michailidis, A Bhatta, F Zhang, ... Journal of Hepatology, S519, 2015 | | 2015 |
Modeling hepatitis B virus infection in primary and in inducible pluripotent stem cell-derived human hepatocytes to study virus-host interactions: 222 RE Schwartz, A Shlomai, V Ramanan, A Bhatta, YP De Jong, S Bhatia, ... Hepatology 60, 310A, 2014 | | 2014 |
Novel in vitro models for assembly of VLDL and low-density hepatitis C virus particles: 1770 U Andreo, MA Scull, YP De Jong, V Ramanan, B Flatley, RE Schwartz, ... Hepatology 60, 1050A-1051A, 2014 | | 2014 |