Mouse embryonic stem cell expansion in a microcarrier-based stirred culture system AM Fernandes, TG Fernandes, MM Diogo, CL da Silva, D Henrique, ... Journal of biotechnology 132 (2), 227-236, 2007 | 218 | 2007 |
Delta one T cells for immunotherapy of chronic lymphocytic leukemia: clinical-grade expansion/differentiation and preclinical proof of concept AR Almeida, DV Correia, A Fernandes-Platzgummer, CL da Silva, ... Clinical Cancer Research 22 (23), 5795-5804, 2016 | 180 | 2016 |
A xenogeneic‐free bioreactor system for the clinical‐scale expansion of human mesenchymal stem/stromal cells F Dos Santos, A Campbell, A Fernandes‐Platzgummer, PZ Andrade, ... Biotechnology and bioengineering 111 (6), 1116-1127, 2014 | 178 | 2014 |
Scalable production of human mesenchymal stromal cell-derived extracellular vesicles under serum-/xeno-free conditions in a microcarrier-based bioreactor culture system M de Almeida Fuzeta, N Bernardes, FD Oliveira, AC Costa, ... Frontiers in Cell and Developmental Biology 8, 553444, 2020 | 101 | 2020 |
Scalable microcarrier-based manufacturing of mesenchymal stem/stromal cells AM de Soure, A Fernandes-Platzgummer, CL da Silva, JMS Cabral Journal of biotechnology 236, 88-109, 2016 | 93 | 2016 |
A xeno‐free microcarrier‐based stirred culture system for the scalable expansion of human mesenchymal stem/stromal cells isolated from bone marrow and adipose tissue JG Carmelo, A Fernandes‐Platzgummer, MM Diogo, CL da Silva, ... Biotechnology journal 10 (8), 1235-1247, 2015 | 85 | 2015 |
Stirred tank bioreactor culture combined with serum‐/xenogeneic‐free culture medium enables an efficient expansion of umbilical cord‐derived mesenchymal stem/stromal cells A Mizukami, A Fernandes‐Platzgummer, JG Carmelo, K Swiech, ... Biotechnology journal 11 (8), 1048-1059, 2016 | 78 | 2016 |
Integrated purification of monoclonal antibodies directly from cell culture medium with aqueous two-phase systems M Silva, A Fernandes-Platzgummer, R Aires-Barros, A Azevedo Separation and Purification Technology 132, 330-335, 2014 | 63 | 2014 |
Integrated culture platform based on a human platelet lysate supplement for the isolation and scalable manufacturing of umbilical cord matrix-derived mesenchymal stem/stromal cells AM de Soure, A Fernandes-Platzgummer, F Moreira, C Lilaia, SH Liu, ... Journal of Tissue Engineering and Regenerative Medicine, doi: 10.1002/term.2200, 2016 | 61 | 2016 |
Scale‐up of mouse embryonic stem cell expansion in stirred bioreactors A Fernandes‐Platzgummer, MM Diogo, RP Baptista, CL Silva, ... Biotechnology progress 27 (5), 1421-1432, 2011 | 53 | 2011 |
Mesenchymal stromal cells induce regulatory T cells via epigenetic conversion of human conventional CD4 T cells in vitro RI Azevedo, E Minskaia, A Fernandes-Platzgummer, AIS Vieira, ... Stem Cells 38 (8), 1007-1019, 2020 | 52 | 2020 |
Different stages of pluripotency determine distinct patterns of proliferation, metabolism, and lineage commitment of embryonic stem cells under hypoxia TG Fernandes, MM Diogo, A Fernandes-Platzgummer, CL da Silva, ... Stem Cell Research 5 (1), 76-89, 2010 | 49 | 2010 |
A fully-closed and automated hollow fiber bioreactor for clinical-grade manufacturing of human mesenchymal stem/stromal cells A Mizukami, MS de Abreu Neto, F Moreira, A Fernandes-Platzgummer, ... Stem cell reviews and reports 14, 141-143, 2018 | 36 | 2018 |
Kinetic and metabolic analysis of mouse embryonic stem cell expansion under serum-free conditions TG Fernandes, AM Fernandes-Platzgummer, CL Da Silva, MM Diogo, ... Biotechnology letters 32, 171-179, 2010 | 31 | 2010 |
Scalable ex vivo expansion of human mesenchymal stem/stromal cells in microcarrier-based stirred culture systems JG Carmelo, A Fernandes-Platzgummer, JMS Cabral, CL da Silva Stem Cells and Good Manufacturing Practices: Methods, Protocols, and …, 2015 | 30 | 2015 |
Microcarrier culture systems for stem cell manufacturing SM Badenes, A Fernandes-Platzgummer, CAV Rodrigues, MM Diogo, ... Stem cell manufacturing, 77-104, 2016 | 27 | 2016 |
Addressing the manufacturing challenges of cell-based therapies M de Almeida Fuzeta, AD de Matos Branco, A Fernandes-Platzgummer, ... Current applications of pharmaceutical biotechnology, 225-278, 2020 | 26 | 2020 |
Clinical-grade manufacturing of therapeutic human mesenchymal stem/stromal cells in microcarrier-based culture systems A Fernandes-Platzgummer, JG Carmelo, CL da Silva, JMS Cabral Mesenchymal Stem Cells: Methods and Protocols, 375-388, 2016 | 24 | 2016 |
Maximizing mouse embryonic stem cell production in a stirred tank reactor by controlling dissolved oxygen concentration and continuous perfusion operation A Fernandes-Platzgummer, MM Diogo, CL da Silva, JMS Cabral Biochemical engineering journal 82, 81-90, 2014 | 22 | 2014 |
Modulation of the in vitro angiogenic potential of human mesenchymal stromal cells from different tissue sources DS Pinto, T Ahsan, J Serra, A Fernandes‐Platzgummer, JMS Cabral, ... Journal of Cellular Physiology 235 (10), 7224-7238, 2020 | 19 | 2020 |