Stem-like CD8 T cells mediate response of adoptive cell immunotherapy against human cancer S Krishna, FJ Lowery, AR Copeland, E Bahadiroglu, R Mukherjee, L Jia, ... Science 370 (6522), 1328-1334, 2020 | 341 | 2020 |
TCR contact residue hydrophobicity is a hallmark of immunogenic CD8+ T cell epitopes D Chowell, S Krishna, PD Becker, C Cocita, J Shu, X Tan, PD Greenberg, ... Proceedings of the National Academy of Sciences 112 (14), E1754-E1762, 2015 | 244 | 2015 |
Molecular signatures of antitumor neoantigen-reactive T cells from metastatic human cancers FJ Lowery, S Krishna, R Yossef, NB Parikh, PD Chatani, N Zacharakis, ... Science 375 (6583), 877-884, 2022 | 217 | 2022 |
Multifunctional CRISPR-Cas9 with engineered immunosilenced human T cell epitopes SR Ferdosi, R Ewaisha, F Moghadam, S Krishna, JG Park, ... Nature communications 10 (1), 1842, 2019 | 172 | 2019 |
Multi-phenotype CRISPR-Cas9 screen identifies p38 kinase as a target for adoptive immunotherapies D Gurusamy, AN Henning, TN Yamamoto, Z Yu, N Zacharakis, S Krishna, ... Cancer cell 37 (6), 818-833. e9, 2020 | 122 | 2020 |
A phenotypic signature that identifies neoantigen-reactive T cells in fresh human lung cancers K Hanada, C Zhao, R Gil-Hoyos, JJ Gartner, C Chow-Parmer, FJ Lowery, ... Cancer Cell 40 (5), 479-493. e6, 2022 | 89 | 2022 |
Human Papilloma Virus Specific Immunogenicity and Dysfunction of CD8+ T Cells in Head and Neck Cancer S Krishna, P Ulrich, E Wilson, F Parikh, P Narang, S Yang, AK Read, ... Cancer research 78 (21), 6159-6170, 2018 | 75 | 2018 |
Adoptive cellular therapy with autologous tumor-infiltrating lymphocytes and T-cell receptor–engineered T cells targeting common p53 neoantigens in human solid tumors SP Kim, NR Vale, N Zacharakis, S Krishna, Z Yu, B Gasmi, JJ Gartner, ... Cancer immunology research 10 (8), 932-946, 2022 | 70 | 2022 |
Modelling the effect of early detection of Ebola D Chowell, C Castillo-Chavez, S Krishna, X Qiu, KS Anderson The Lancet Infectious Diseases 15 (2), 148-149, 2015 | 66 | 2015 |
JAK2 and PD-L1 amplification enhance the dynamic expression of PD-L1 in triple-negative breast cancer M Chen, B Pockaj, M Andreozzi, MT Barrett, S Krishna, S Eaton, R Niu, ... Clinical breast cancer 18 (5), e1205-e1215, 2018 | 59 | 2018 |
A machine learning model for ranking candidate HLA class I neoantigens based on known neoepitopes from multiple human tumor types JJ Gartner, MR Parkhurst, A Gros, E Tran, MS Jafferji, A Copeland, ... Nature cancer 2 (5), 563-574, 2021 | 50 | 2021 |
Rapid identification and evaluation of neoantigen-reactive T-cell receptors from single cells BC Paria, N Levin, FJ Lowery, A Pasetto, DC Deniger, MR Parkhurst, ... Journal of Immunotherapy 44 (1), 1-8, 2021 | 26 | 2021 |
Neoantigen identification and response to adoptive cell transfer in anti–PD-1 naïve and experienced patients with metastatic melanoma ST Levi, AR Copeland, S Nah, JS Crystal, GD Ivey, A Lalani, M Jafferji, ... Clinical cancer research 28 (14), 3042-3052, 2022 | 25 | 2022 |
T-cell epitope discovery for therapeutic cancer vaccines S Krishna, KS Anderson Vaccine Design: Methods and Protocols: Volume 1: Vaccines for Human Diseases …, 2016 | 20 | 2016 |
High throughput identification of t-cell recognition antigens and epitopes J Labaer, K Anderson, J Qiu, S Krishna US Patent App. 15/770,323, 2018 | 12 | 2018 |
Cell surface marker-based capture of neoantigen-reactive CD8+ T-cell receptors from metastatic tumor digests PD Chatani, FJ Lowery, NB Parikh, KJ Hitscherich, R Yossef, V Hill, ... Journal for ImmunoTherapy of Cancer 11 (5), 2023 | 10 | 2023 |
Phenotypic signatures of circulating neoantigen-reactive CD8+ T cells in patients with metastatic cancers R Yossef, S Krishna, S Sindiri, FJ Lowery, AR Copeland, JJ Gartner, ... Cancer Cell 41 (12), 2154-2165. e5, 2023 | 6 | 2023 |
A Random Forest based approach to MHC class I epitope prediction and analysis EA Wilson, S Krishna, KS Anderson The Journal of Immunology 200 (1_Supplement), 99.11-99.11, 2018 | 4 | 2018 |
Single-cell analysis of circulating neoantigen-reactive CD8+ T cells allows isolation of novel tumor reactive TCRs R Yoseph, S Krishna, FJ Lowery, AR Copeland, NB Parikh, K Hitscherich, ... Cancer Research 82 (12_Supplement), 2762-2762, 2022 | 3 | 2022 |
Modulating human Cas9-specific host immune response R Ewaisha, S Kiani, SR Ferdosi, K Anderson, F Moghadam, S Krishna, ... US Patent 11,208,640, 2021 | 2 | 2021 |