C9ORF72 repeat expansion causes vulnerability of motor neurons to Ca2+-permeable AMPA receptor-mediated excitotoxicity BT Selvaraj, MR Livesey, C Zhao, JM Gregory, OT James, EM Cleary, ... Nature communications 9 (1), 347, 2018 | 199 | 2018 |
Truncated stathmin-2 is a marker of TDP-43 pathology in frontotemporal dementia M Prudencio, J Humphrey, S Pickles, AL Brown, SE Hill, JM Kachergus, ... The Journal of clinical investigation 130 (11), 2020 | 137 | 2020 |
Mitochondrial bioenergetic deficits in C9orf72 amyotrophic lateral sclerosis motor neurons cause dysfunctional axonal homeostasis AR Mehta, JM Gregory, O Dando, RN Carter, K Burr, J Nanda, D Story, ... Acta neuropathologica 141, 257-279, 2021 | 102 | 2021 |
Mutant C9orf72 human iPSC‐derived astrocytes cause non‐cell autonomous motor neuron pathophysiology C Zhao, AC Devlin, AK Chouhan, BT Selvaraj, M Stavrou, K Burr, V Brivio, ... Glia 68 (5), 1046-1064, 2020 | 101 | 2020 |
Local axonal function of STAT3 rescues axon degeneration in the pmn model of motoneuron disease BT Selvaraj, N Frank, FLP Bender, E Asan, M Sendtner Journal of Cell Biology 199 (3), 437-451, 2012 | 91 | 2012 |
Maturation and electrophysiological properties of human pluripotent stem cell-derived oligodendrocytes MR Livesey, D Magnani, EM Cleary, NA Vasistha, OT James, BT Selvaraj, ... Stem cells 34 (4), 1040-1053, 2016 | 74 | 2016 |
C9orf72-derived arginine-containing dipeptide repeats associate with axonal transport machinery and impede microtubule-based motility L Fumagalli, FL Young, S Boeynaems, M De Decker, AR Mehta, ... Science Advances 7 (15), eabg3013, 2021 | 69 | 2021 |
Hypothermic preconditioning of human cortical neurons requires proteostatic priming NM Rzechorzek, P Connick, R Patani, BT Selvaraj, S Chandran EBioMedicine 2 (6), 528-535, 2015 | 53 | 2015 |
Dysregulation of AMPA receptor subunit expression in sporadic ALS post‐mortem brain JM Gregory, MR Livesey, K McDade, BT Selvaraj, SK Barton, S Chandran, ... The Journal of pathology 250 (1), 67-78, 2020 | 49 | 2020 |
iPSC-derived myelinoids to study myelin biology of humans OG James, BT Selvaraj, D Magnani, K Burr, P Connick, SK Barton, ... Developmental Cell 56 (9), 1346-1358. e6, 2021 | 47 | 2021 |
Altered network properties in C9ORF72 repeat expansion cortical neurons are due to synaptic dysfunction EM Perkins, K Burr, P Banerjee, AR Mehta, O Dando, BT Selvaraj, ... Molecular neurodegeneration 16, 1-16, 2021 | 44 | 2021 |
Evidence for evolutionary divergence of activity-dependent gene expression in developing neurons J Qiu, J McQueen, B Bilican, O Dando, D Magnani, K Punovuori, ... Elife 5, e20337, 2016 | 36 | 2016 |
Neurofilament depletion improves microtubule dynamics via modulation of Stat3/stathmin signaling P Yadav, BT Selvaraj, FLP Bender, M Behringer, M Moradi, R Sivadasan, ... Acta neuropathologica 132, 93-110, 2016 | 29 | 2016 |
Targeting mitochondrial dysfunction in amyotrophic lateral sclerosis: a systematic review and meta-analysis AR Mehta, R Walters, FM Waldron, S Pal, BT Selvaraj, MR Macleod, ... Brain communications 1 (1), fcz009, 2019 | 28 | 2019 |
FMRP interacts with C/D box snoRNA in the nucleus and regulates ribosomal RNA methylation MN D'Souza, NKC Gowda, V Tiwari, RO Babu, P Anand, SG Dastidar, ... IScience 9, 399-411, 2018 | 25 | 2018 |
CNTF, STAT3 and new therapies for axonal degeneration: what are they and what can they do? BT Selvaraj, M Sendtner Expert Review of Neurotherapeutics 13 (3), 239-241, 2013 | 20 | 2013 |
Cell-autonomous immune dysfunction driven by disrupted autophagy in C9orf72-ALS iPSC-derived microglia contributes to neurodegeneration P Banerjee, AR Mehta, RS Nirujogi, J Cooper, OG James, J Nanda, ... Science Advances 9 (16), eabq0651, 2023 | 18 | 2023 |
Modeling the C9ORF72 repeat expansion mutation using human induced pluripotent stem cells BT Selvaraj, MR Livesey, S Chandran Brain Pathology 27 (4), 518-524, 2017 | 18 | 2017 |
Familial t (1; 11) translocation is associated with disruption of white matter structural integrity and oligodendrocyte–myelin dysfunction NA Vasistha, M Johnstone, SK Barton, SE Mayerl, B Thangaraj Selvaraj, ... Molecular psychiatry 24 (11), 1641-1654, 2019 | 17 | 2019 |
Generation of twenty four induced pluripotent stem cell lines from twenty four members of the Lothian Birth Cohort 1936 J Toombs, L Panther, L Ornelas, C Liu, E Gomez, R Martín-Ibáñez, ... Stem cell research 46, 101851, 2020 | 15 | 2020 |