Efficient genome modification by CRISPR-Cas9 nickase with minimal off-target effects B Shen, W Zhang, J Zhang, J Zhou, J Wang, L Chen, L Wang, A Hodgkins, ... Nature methods 11 (4), 399-402, 2014 | 980 | 2014 |
Reciprocal Transcriptional Regulation of Pou5f1 and Sox2 via the Oct4/Sox2 Complex in Embryonic Stem Cells JL Chew, YH Loh, W Zhang, X Chen, WL Tam, LS Yeap, P Li, YS Ang, ... Molecular and cellular biology 25 (14), 6031-6046, 2005 | 910 | 2005 |
The Drosophila Ste20 family kinase dMST functions as a tumor suppressor by restricting cell proliferation and promoting apoptosis J Jia, W Zhang, B Wang, R Trinko, J Jiang Genes & development 17 (20), 2514-2519, 2003 | 455 | 2003 |
Sall4 interacts with Nanog and co-occupies Nanog genomic sites in embryonic stem cells Q Wu, X Chen, J Zhang, YH Loh, TY Low, W Zhang, W Zhang, SK Sze, ... Journal of Biological Chemistry 281 (34), 24090-24094, 2006 | 370 | 2006 |
Off-target mutations are rare in Cas9-modified mice V Iyer, B Shen, W Zhang, A Hodgkins, T Keane, X Huang, WC Skarnes Nature methods 12 (6), 479-479, 2015 | 213 | 2015 |
Hedgehog-regulated Costal2-kinase complexes control phosphorylation and proteolytic processing of Cubitus interruptus W Zhang, Y Zhao, C Tong, G Wang, B Wang, J Jia, J Jiang Developmental cell 8 (2), 267-278, 2005 | 213 | 2005 |
Efficient in vivo deletion of a large imprinted lncRNA by CRISPR/Cas9 J Han, J Zhang, L Chen, B Shen, J Zhou, B Hu, Y Du, PH Tate, X Huang, ... RNA biology 11 (7), 829-835, 2014 | 196 | 2014 |
Estrogen-Related Receptor Beta Interacts with Oct4 To Positively Regulate Nanog Gene Expression DLC van den Berg, W Zhang, A Yates, E Engelen, K Takacs, K Bezstarosti, ... Molecular and cellular biology 28 (19), 5986-5995, 2008 | 192 | 2008 |
Dual sgRNAs facilitate CRISPR/Cas9‐mediated mouse genome targeting J Zhou, J Wang, B Shen, L Chen, Y Su, J Yang, W Zhang, X Tian, ... The FEBS journal 281 (7), 1717-1725, 2014 | 179 | 2014 |
OCT4/SOX2‐independent Nanog autorepression modulates heterogeneous Nanog gene expression in mouse ES cells P Navarro, N Festuccia, D Colby, A Gagliardi, NP Mullin, W Zhang, ... The EMBO journal 31 (24), 4547-4562, 2012 | 178 | 2012 |
One-step generation of different immunodeficient mice with multiple gene modifications by CRISPR/Cas9 mediated genome engineering J Zhou, B Shen, W Zhang, J Wang, J Yang, L Chen, N Zhang, K Zhu, J Xu, ... The international journal of biochemistry & cell biology 46, 49-55, 2014 | 155 | 2014 |
Hippo-YAP signaling controls lineage differentiation of mouse embryonic stem cells through modulating the formation of super-enhancers X Sun, Z Ren, Y Cun, C Zhao, X Huang, J Zhou, R Hu, X Su, L Ji, P Li, ... Nucleic acids research 48 (13), 7182-7196, 2020 | 52 | 2020 |
Rice HMGB1 protein recognizes DNA structures and bends DNA efficiently Q Wu, W Zhang, KH Pwee, PP Kumar Archives of biochemistry and biophysics 411 (1), 105-111, 2003 | 45 | 2003 |
Cloning and characterization of rice HMGB1 gene Q Wu, W Zhang, KH Pwee, PP Kumar Gene 312, 103-109, 2003 | 43 | 2003 |
The BAF and PRC2 complex subunits Dpf2 and Eed antagonistically converge on Tbx3 to control ESC differentiation W Zhang, C Chronis#, X Chen#, H Zhang, R Spalinskas, M Pardo, L Chen, ... Cell Stem Cell 24 (1), 138-152, 2019 | 38 | 2019 |
Interaction of wheat high-mobility-group proteins with four-way-junction DNA and characterization of the structure and expression of HMGA gene W Zhang, Q Wu, KH Pwee, RM Kini Archives of biochemistry and biophysics 409 (2), 357-366, 2003 | 34 | 2003 |
Efficient knockin mouse generation by ssDNA oligonucleotides and zinc-finger nuclease assisted homologous recombination in zygotes B Shen, X Zhang, Y Du, J Wang, J Gong, X Zhang, PH Tate, H Li, ... PLoS One 8 (10), e77696, 2013 | 25 | 2013 |
Mammalian SWI/SNF chromatin remodeling complexes in embryonic stem cells: regulating the balance between pluripotency and differentiation Y Ye, X Chen, W Zhang Frontiers in cell and developmental biology 8, 626383, 2021 | 19 | 2021 |
Characterization of the interaction of wheat HMGa with linear and four-way junction DNAs W Zhang, Q Wu, KH Pwee, SDS Jois, RM Kini Biochemistry 42 (21), 6596-6607, 2003 | 14 | 2003 |
SPEED: single-cell pan-species atlas in the light of ecology and evolution for development and diseases Y Chen, X Zhang, X Peng, Y Jin, P Ding, J Xiao, C Li, F Wang, A Chang, ... Nucleic acids research 51 (D1), D1150-D1159, 2023 | 13 | 2023 |