| Biocatalytic reductive amination from discovery to commercial manufacturing applied to abrocitinib JAK1 inhibitor R Kumar, MJ Karmilowicz, D Burke, MP Burns, LA Clark, CG Connor, ... Nature Catalysis 4 (9), 775-782, 2021 | 91 | 2021 |
| A chemoenzymatic route to chiral intermediates used in the multikilogram synthesis of a gamma secretase inhibitor M Burns, CA Martinez, B Vanderplas, R Wisdom, S Yu, RA Singer Organic Process Research & Development 21 (6), 871-877, 2017 | 41 | 2017 |
| Application of Biocatalytic Reductive Amination for the Synthesis of a Key Intermediate to a CDK 2/4/6 Inhibitor S Duan, DW Widlicka, MP Burns, R Kumar, I Hotham, JN Desrosiers, ... Organic Process Research & Development 26 (3), 879-890, 2021 | 28 | 2021 |
| Biocatalytic oxidation of 2-methylquinoxaline to 2-quinoxalinecarboxylic acid JW Wong, HA Watson, JF Bouressa, MP Burns, JJ Cawley, AE Doro, ... Organic process research & development 6 (4), 477-481, 2002 | 26 | 2002 |
| Ketoreductase/Transaminase, one-pot, multikilogram biocatalytic Cascade Reaction M Burns, W Bi, H Kim, MS Lall, C Li, BT O’Neill Organic Process Research & Development 25 (4), 941-946, 2021 | 18 | 2021 |
| Application of Flow and Biocatalytic Transaminase Technology for the Synthesis of a 1-Oxa-8-azaspiro [4.5] decan-3-amine JT Kohrt, PH Dorff, M Burns, C Lee, SV O’Neil, RJ Maguire, R Kumar, ... Organic Process Research & Development 26 (3), 616-623, 2021 | 14 | 2021 |
| Application of biocatalysis towards asymmetric reduction and hydrolytic desymmetrisation in the synthesis of a β-3 receptor agonist M Badland, MP Burns, RJ Carroll, RM Howard, D Laity, NJ Wymer Green Chemistry 13 (10), 2888-2894, 2011 | 13 | 2011 |
| Alternate synthesis of a β-3 adrenergic receptor agonist RW Scott, DE Fox, JW Wong, MP Burns Organic process research & development 8 (4), 587-592, 2004 | 12 | 2004 |
| Stereoselective bioconversion of aliphatic dinitriles into cyano carboxylic acids MP Burns, JK Weaver, JW Wong US Patent 8,304,252, 2012 | 11 | 2012 |
| Stereoselective bioconversion of aliphatic dinitriles into cyano carboxylic acids MP Burns, JK Weaver, JW Wong US Patent 7,727,749, 2010 | 11 | 2010 |
| Biocatalytic preparation of 1-cyano-cyclohexaneacetic acid J Wong, M Burns US Patent App. 10/869,518, 2005 | 8 | 2005 |
| Microbial hydroxylation of (Z)-2-benzylidene-1-azabicyclo [2.2. 2] octan-3-one JW Wong, MP Burns Tetrahedron: Asymmetry 10 (22), 4295-4305, 1999 | 8 | 1999 |
| Engineering of a Reductive Aminase to Enable the Synthesis of a Key Intermediate to a CDK 2/4/6 Inhibitor J Steflik, A Gilio, M Burns, G Grogan, R Kumar, R Lewis, C Martinez ACS Catalysis 13 (15), 10065-10075, 2023 | 6 | 2023 |
| Microbial asymmetric reduction of 2-chloro-1-[-6-(2, 5-dimethyl-pyrrol-1-yl)-pyridin-3-yl]-ethanone MP Burns, JW Wong US Patent 6,451,587, 2002 | 6 | 2002 |
| Process for the synthesis of cis-1, 3-diols MP Burns, JW Wong US Patent App. 11/941,485, 2008 | 2 | 2008 |
| Microbial conversion of 2-methylquinoxaline MP Burns, JJ Cawley, JW Wong US Patent 6,361,979, 2002 | 1 | 2002 |
| Protein engineering of the sorbose reductase from Candida albicans for the production of a biocatalyst capable of substrate coupled cofactor recycle MP Burns Quinnipiac University, 2013 | | 2013 |
| Industrial Carbonyl Reduction DP Mangan, TS Moody, O Gooding, GW Huisman, CA Martinez, ... Practical Methods for Biocatalysis and Biotransformations 2, 115-127, 2012 | | 2012 |
| 4.3 Enzymatic Reduction of 2, 6-dichloro-3-fluoro-acetophenone to Produce (S)-1-(2, 6-dichloro-3-fluorophenyl) ethanol CA Martinez, A Smogowicz, JS Steflik, MS Brown, KS Midelfort, MP Burns, ... Practical Methods for Biocatalysis and Biotransformations 2 2101, 121, 2010 | | 2010 |
| Transformação microbiana de 2-metilquinoxalina MP Burns, JJ Cawley, JW Wong | | 2001 |
