Highly efficient production of soluble proteins from insoluble inclusion bodies by a two-step-denaturing and refolding method Z Yang, L Zhang, Y Zhang, T Zhang, Y Feng, X Lu, W Lan, J Wang, H Wu, ... PloS one 6 (7), e22981, 2011 | 162 | 2011 |
Structure of the Rpn13-Rpn2 complex provides insights for Rpn13 and Uch37 as anticancer targets X Lu, U Nowicka, V Sridharan, F Liu, L Randles, D Hymel, M Dyba, ... Nature communications 8 (1), 15540, 2017 | 78 | 2017 |
Evolutionary diversification of Mesobuthus α-scorpion toxins affecting sodium channels S Zhu, S Peigneur, B Gao, X Lu, C Cao, J Tytgat Molecular & Cellular Proteomics 11 (1), 2012 | 64 | 2012 |
Crystal structure of DNA cytidine deaminase ABOBEC3G catalytic deamination domain suggests a binding mode of full-length enzyme to single-stranded DNA X Lu, T Zhang, Z Xu, S Liu, B Zhao, W Lan, C Wang, J Ding, C Cao Journal of Biological Chemistry 290 (7), 4010-4021, 2015 | 56 | 2015 |
Covalent Rpn13-binding inhibitors for the treatment of ovarian cancer RK Anchoori, R Jiang, S Peng, R Soong, A Algethami, MA Rudek, ... ACS omega 3 (9), 11917-11929, 2018 | 33 | 2018 |
A high affinity hRpn2-derived peptide that displaces human Rpn13 from proteasome in 293T cells X Lu, F Liu, SE Durham, SG Tarasov, KJ Walters PLoS One 10 (10), e0140518, 2015 | 29 | 2015 |
An extended conformation for K48 ubiquitin chains revealed by the hRpn2: Rpn13: K48-diubiquitin structure X Lu, DL Ebelle, H Matsuo, KJ Walters Structure 28 (5), 495-506. e3, 2020 | 25 | 2020 |
Structure-guided bifunctional molecules hit a DEUBAD-lacking hRpn13 species upregulated in multiple myeloma X Lu, VR Sabbasani, V Osei-Amponsa, CN Evans, JC King, SG Tarasov, ... Nature Communications 12 (1), 7318, 2021 | 21 | 2021 |
hRpn13 shapes the proteome and transcriptome through epigenetic factors HDAC8, PADI4, and transcription factor NF-κB p50 V Osei-Amponsa, M Chandravanshi, X Lu, V Magidson, S Das, ... Molecular Cell 84 (3), 522-537. e8, 2024 | 3 | 2024 |
Exploiting the Proteasome for Disease Treatment: From Dynamic Architecture to Vast Functions GR Buel, X Lu, KJ Walters Protein Homeostasis in Drug Discovery: A Chemical Biology Perspective, 135-177, 2022 | 1 | 2022 |
A structure-based designed small molecule depletes hRpn13Pru and a select group of KEN box proteins X Lu, M Chandravanshi, VR Sabbasani, S Gaikwad, VK Hughitt, ... Nature Communications 15 (1), 2485, 2024 | | 2024 |
Structure of hRpn13 at the Proteasome X Lu, F Liu, U Nowicka, V Sridharan, M Dyba, SG Tarasov, KJ Walters The FASEB Journal 31, 603.5-603.5, 2017 | | 2017 |
A New Conformation for K48 Ubiquitin Chains Revealed by the hRpn2: Rpn13: K48-Diubiquitin Structure X Lu, D Ebelle, H Matsuo, KJ Walters Available at SSRN 3508886, 0 | | |