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Xiuxiu Lu
Xiuxiu Lu
NCI-Frederick/NIH, SIOC-China
在 nih.gov 的电子邮件经过验证
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引用次数
引用次数
年份
Highly efficient production of soluble proteins from insoluble inclusion bodies by a two-step-denaturing and refolding method
Z Yang, L Zhang, Y Zhang, T Zhang, Y Feng, X Lu, W Lan, J Wang, H Wu, ...
PloS one 6 (7), e22981, 2011
1622011
Structure of the Rpn13-Rpn2 complex provides insights for Rpn13 and Uch37 as anticancer targets
X Lu, U Nowicka, V Sridharan, F Liu, L Randles, D Hymel, M Dyba, ...
Nature communications 8 (1), 15540, 2017
782017
Evolutionary diversification of Mesobuthus α-scorpion toxins affecting sodium channels
S Zhu, S Peigneur, B Gao, X Lu, C Cao, J Tytgat
Molecular & Cellular Proteomics 11 (1), 2012
642012
Crystal structure of DNA cytidine deaminase ABOBEC3G catalytic deamination domain suggests a binding mode of full-length enzyme to single-stranded DNA
X Lu, T Zhang, Z Xu, S Liu, B Zhao, W Lan, C Wang, J Ding, C Cao
Journal of Biological Chemistry 290 (7), 4010-4021, 2015
562015
Covalent Rpn13-binding inhibitors for the treatment of ovarian cancer
RK Anchoori, R Jiang, S Peng, R Soong, A Algethami, MA Rudek, ...
ACS omega 3 (9), 11917-11929, 2018
332018
A high affinity hRpn2-derived peptide that displaces human Rpn13 from proteasome in 293T cells
X Lu, F Liu, SE Durham, SG Tarasov, KJ Walters
PLoS One 10 (10), e0140518, 2015
292015
An extended conformation for K48 ubiquitin chains revealed by the hRpn2: Rpn13: K48-diubiquitin structure
X Lu, DL Ebelle, H Matsuo, KJ Walters
Structure 28 (5), 495-506. e3, 2020
252020
Structure-guided bifunctional molecules hit a DEUBAD-lacking hRpn13 species upregulated in multiple myeloma
X Lu, VR Sabbasani, V Osei-Amponsa, CN Evans, JC King, SG Tarasov, ...
Nature Communications 12 (1), 7318, 2021
212021
hRpn13 shapes the proteome and transcriptome through epigenetic factors HDAC8, PADI4, and transcription factor NF-κB p50
V Osei-Amponsa, M Chandravanshi, X Lu, V Magidson, S Das, ...
Molecular Cell 84 (3), 522-537. e8, 2024
32024
Exploiting the Proteasome for Disease Treatment: From Dynamic Architecture to Vast Functions
GR Buel, X Lu, KJ Walters
Protein Homeostasis in Drug Discovery: A Chemical Biology Perspective, 135-177, 2022
12022
A structure-based designed small molecule depletes hRpn13Pru and a select group of KEN box proteins
X Lu, M Chandravanshi, VR Sabbasani, S Gaikwad, VK Hughitt, ...
Nature Communications 15 (1), 2485, 2024
2024
Structure of hRpn13 at the Proteasome
X Lu, F Liu, U Nowicka, V Sridharan, M Dyba, SG Tarasov, KJ Walters
The FASEB Journal 31, 603.5-603.5, 2017
2017
A New Conformation for K48 Ubiquitin Chains Revealed by the hRpn2: Rpn13: K48-Diubiquitin Structure
X Lu, D Ebelle, H Matsuo, KJ Walters
Available at SSRN 3508886, 0
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