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Francis Ayombil, Ph.D.
Francis Ayombil, Ph.D.
Children's Hospital of Philadelphia - Univ. of Pennsylvania
在 email.chop.edu 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
Regulation of factor V and factor V-short by TFPIα: relationship between B-domain proteolysis and binding
T Petrillo, F Ayombil, C van’t Veer, RM Camire
Journal of Biological Chemistry 296, 2021
332021
Microbial detheobromination of cocoa (Theobroma cacao) pod husk.
NA Adamafio, F Ayombil, K Tano-Debrah
322011
Proteolysis of plasma‐derived factor V following its endocytosis by megakaryocytes forms the platelet‐derived factor V/Va pool
F Ayombil, S Abdalla, PB Tracy, BA Bouchard
Journal of Thrombosis and Haemostasis 11 (8), 1532-1539, 2013
262013
Insights into vitamin K-dependent carboxylation: home field advantage
F Ayombil, RM Camire
Haematologica 105 (8), 1996, 2020
92020
Plasma growth factors maintain constitutive translation in platelets to regulate reactivity and thrombotic potential
JGT Wurtzel, S Lazar, S Askari, X Zhao, J Severa, F Ayombil, JV Michael, ...
Blood Advances 8 (6), 1550-1566, 2024
82024
Activation of Piezo1 channels in compressed red blood cells augments platelet-driven contraction of blood clots
NG Evtugina, AD Peshkova, AI Khabirova, IA Andrianova, S Abdullayeva, ...
Journal of Thrombosis and Haemostasis 21 (9), 2418-2429, 2023
82023
Regulation of factor V by the anticoagulant protease activated protein C: Influence of the B-domain and TFPIα
F Ayombil, T Petrillo, H Kim, RM Camire
Journal of Biological Chemistry 298 (11), 2022
62022
Voices on diversity: creating a sense of belonging
L McGill, D Brooks, J Joseph, J Silva-Fisher, S Guerrier, T Addo, A Guerra, ...
Molecular Cell 81 (2), 213-217, 2021
42021
A Novel Approach for Generating Platelet-Delivered FVIII: Role of Transient LRP1 Expression during Megakaryopoiesis
J Tkaczynski, R Lyde, H Ahn, F Ayombil, S Borst, P Gadue, DL French, ...
Blood 134, 1102, 2019
32019
Voices on diversity: recruiting underrepresented scientists
J Joseph, J Johnson, F Ayombil, J Silva-Fisher, S Guerrier, LM Nervo, ...
Molecular cell 81 (3), 414-417, 2021
22021
Voices on Diversity: Combating Racial Inequality to Increase Diversity
J Silva-Fisher, S Guerrier, LM Nervo, A Guerra, L McGill, D Brooks, ...
Molecular cell 81 (1), 1-5, 2021
22021
Voices on diversity: multiple paths to becoming a scientist
J Silva-Fisher, LM Nervo, T Addo, A Guerra, M Walker, S Guerrier, ...
Molecular cell 80 (5), 752-757, 2020
22020
Voices on diversity: support systems that work
LM Nervo, F Ayombil, T Addo, A Guerra, M Walker, L McGill, J Joseph, ...
Molecular cell 81 (5), 885-888, 2021
12021
PB0538 A Monoclonal Antibody against Human Factor V Impairs its Activation and Procoagulant Function
F Ayombil, S Quinn, E Cid, M Bunce, R Camire
Research and Practice in Thrombosis and Haemostasis 7, 2023
2023
An Antibody Targeting Human FV Promotes Thrombin Generation and Reduces Bleeding in a Hemophilic Mouse Model
S Quinn, L Ivanciu, RJ Davidson, F Ayombil, RM Camire
Blood 140 (Supplement 1), 963-964, 2022
2022
Protection of Human Factor V from Activated Protein C Using a Monoclonal Antibody-Biochemical Characterization and Evaluation Using a Mouse Injury Model
S Quinn, L Ivanciu, RJ Davidson, F Ayombil, J Crosby, A Revenko, ...
Blood 138, 2092, 2021
2021
Acidic and basic residues within factor V B-domain impacts downregulation by APC
F Ayombil, T Petrillo, R Camire
HAEMOPHILIA 25, 8-9, 2019
2019
Defining platelet-derived components regulating the Prothrombinase enzyme complex
F Ayombil
The University of Vermont and State Agricultural College, 2016
2016
Fragment-2 inhibition of prothrombinase reveals a unique enzyme-substrate interface for the platelet-bound enzyme
F Ayombil, LM Haynes, PB Tracy
JOURNAL OF THROMBOSIS AND HAEMOSTASIS 13, 557-557, 2015
2015
Prethrombin-1, the Gla-domainless prothrombin intermediate, is activated efficiently to thrombin by prothrombinase assembled on the activated platelet surface
PB Tracy, F Ayombil, JR Silveira, JP Wood
JOURNAL OF THROMBOSIS AND HAEMOSTASIS 9, 352-352, 2011
2011
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