Cannabidiol modulates serotonergic transmission and reverses both allodynia and anxiety-like behavior in a model of neuropathic pain D De Gregorio, RJ McLaughlin, L Posa, R Ochoa-Sanchez, J Enns, ... Pain 160 (1), 136-150, 2019 | 358 | 2019 |
Antibiotic-induced microbiota perturbation causes gut endocannabinoidome changes, hippocampal neuroglial reorganization and depression in mice F Guida, F Turco, M Iannotta, D De Gregorio, I Palumbo, G Sarnelli, ... Brain, behavior, and immunity 67, 230-245, 2018 | 293 | 2018 |
Hallucinogens in mental health: preclinical and clinical studies on LSD, psilocybin, MDMA, and ketamine D De Gregorio, A Aguilar-Valles, KH Preller, BD Heifets, M Hibicke, ... Journal of Neuroscience 41 (5), 891-900, 2021 | 162 | 2021 |
Psychedelics in psychiatry: neuroplastic, immunomodulatory, and neurotransmitter mechanisms A Inserra, D De Gregorio, G Gobbi Pharmacological Reviews 73 (1), 202-277, 2021 | 160 | 2021 |
d-Lysergic Acid Diethylamide (LSD) as a Model of Psychosis: Mechanism of Action and Pharmacology D De Gregorio, S Comai, L Posa, G Gobbi International journal of molecular sciences 17 (11), 1953, 2016 | 130 | 2016 |
Palmitoylethanolamide reduces pain-related behaviors and restores glutamatergic synapses homeostasis in the medial prefrontal cortex of neuropathic mice F Guida, L Luongo, F Marmo, R Romano, M Iannotta, F Napolitano, ... Molecular brain 8, 1-15, 2015 | 120 | 2015 |
Antidepressant actions of ketamine engage cell-specific translation via eIF4E A Aguilar-Valles, D De Gregorio, E Matta-Camacho, MJ Eslamizade, ... Nature 590 (7845), 315-319, 2021 | 94 | 2021 |
d-Lysergic acid diethylamide, psilocybin, and other classic hallucinogens: mechanism of action and potential therapeutic applications in mood disorders D De Gregorio, JP Enns, NA Nuñez, L Posa, G Gobbi Progress in brain research 242, 69-96, 2018 | 94 | 2018 |
The hallucinogen d-lysergic diethylamide (LSD) decreases dopamine firing activity through 5-HT1A, D2 and TAAR1 receptors D De Gregorio, L Posa, R Ochoa-Sanchez, R McLaughlin, S Maione, ... Pharmacological Research 113, 81-91, 2016 | 93 | 2016 |
Behavioral, biochemical and electrophysiological changes in spared nerve injury model of neuropathic pain F Guida, D De Gregorio, E Palazzo, F Ricciardi, S Boccella, C Belardo, ... International journal of molecular sciences 21 (9), 3396, 2020 | 82 | 2020 |
Genetic deletion of monoacylglycerol lipase leads to impaired cannabinoid receptor CB1R signaling and anxiety‐like behavior R Imperatore, G Morello, L Luongo, U Taschler, R Romano, ... Journal of neurochemistry 135 (4), 799-813, 2015 | 82 | 2015 |
Translational control of depression-like behavior via phosphorylation of eukaryotic translation initiation factor 4E A Aguilar-Valles, N Haji, D De Gregorio, E Matta-Camacho, ... Nature communications 9 (1), 2459, 2018 | 79 | 2018 |
Lysergic acid diethylamide (LSD) promotes social behavior through mTORC1 in the excitatory neurotransmission D De Gregorio, J Popic, JP Enns, A Inserra, A Skalecka, A Markopoulos, ... Proceedings of the National Academy of Sciences 118 (5), e2020705118, 2021 | 75 | 2021 |
Targeting melatonin MT2 receptors: a novel pharmacological avenue for inflammatory and neuropathic pain L Posa, D De Gregorio, G Gobbi, S Comai Current medicinal chemistry 25 (32), 3866-3882, 2018 | 65 | 2018 |
Alterations of brain and cerebellar proteomes linked to Aβ and tau pathology in a female triple-transgenic murine model of Alzheimer's disease D Ciavardelli, E Silvestri, A Del Viscovo, M Bomba, D De Gregorio, ... Cell death & disease 1 (10), e90-e90, 2010 | 63 | 2010 |
MMPIP, an mGluR7-selective negative allosteric modulator, alleviates pain and normalizes affective and cognitive behavior in neuropathic mice E Palazzo, R Romano, L Luongo, S Boccella, D De Gregorio, ... Pain 156 (6), 1060-1073, 2015 | 61 | 2015 |
Repeated lysergic acid diethylamide (LSD) reverses stress-induced anxiety-like behavior, cortical synaptogenesis deficits and serotonergic neurotransmission decline D De Gregorio, A Inserra, JP Enns, A Markopoulos, M Pileggi, ... Neuropsychopharmacology 47 (6), 1188-1198, 2022 | 52 | 2022 |
Palmitoylethanolamide reduces neuropsychiatric behaviors by restoring cortical electrophysiological activity in a mouse model of mild traumatic brain injury F Guida, S Boccella, M Iannotta, D De Gregorio, C Giordano, C Belardo, ... Frontiers in Pharmacology 8, 95, 2017 | 51 | 2017 |
Ketones and pain: unexplored role of hydroxyl carboxylic acid receptor type 2 in the pathophysiology of neuropathic pain S Boccella, F Guida, F De Logu, D De Gregorio, M Mazzitelli, C Belardo, ... The FASEB Journal 33 (1), 1062-1073, 2019 | 46 | 2019 |
Melatonin MT1 receptor as a novel target in neuropsychopharmacology: MT1 ligands, pathophysiological and therapeutic implications, and perspectives S Comai, M Lopez-Canul, D De Gregorio, A Posner, M Ettaoussi, ... Pharmacological research 144, 343-356, 2019 | 44 | 2019 |