Yeast Mph1 helicase dissociates Rad51-made D-loops: implications for crossover control in mitotic recombination R Prakash, D Satory, E Dray, A Papusha, J Scheller, W Kramer, L Krejci, ... Genes & development 23 (1), 67-79, 2009 | 300 | 2009 |
Brca2 is involved in meiosis in Arabidopsis thaliana as suggested by its interaction with Dmc1 N Siaud, E Dray, I Gy, E Gérard, N Takvorian, MP Doutriaux The EMBO journal 23 (6), 1392-1401, 2004 | 220 | 2004 |
Enhancement of RAD51 recombinase activity by the tumor suppressor PALB2 E Dray, J Etchin, C Wiese, D Saro, GJ Williams, M Hammel, X Yu, ... Nature structural & molecular biology 17 (10), 1255-1259, 2010 | 192 | 2010 |
Promotion of homologous recombination and genomic stability by RAD51AP1 via RAD51 recombinase enhancement C Wiese, E Dray, T Groesser, J San Filippo, I Shi, DW Collins, MS Tsai, ... Molecular cell 28 (3), 482-490, 2007 | 155 | 2007 |
Targeting cancer with a lupus autoantibody JE Hansen, G Chan, Y Liu, DC Hegan, S Dalal, E Dray, Y Kwon, Y Xu, ... Science translational medicine 4 (157), 157ra142-157ra142, 2012 | 108 | 2012 |
Targeting DNA damage response and replication stress in pancreatic cancer SB Dreyer, R Upstill-Goddard, V Paulus-Hock, C Paris, EM Lampraki, ... Gastroenterology 160 (1), 362-377. e13, 2021 | 105 | 2021 |
Interaction between Arabidopsis BRCA2 and its partners RAD51, DMC1, and DSS1 E Dray, N Siaud, E Dubois, MP Doutriaux Plant Physiology 140 (3), 1059-1069, 2006 | 94 | 2006 |
Chromosome arm aneuploidies shape tumour evolution and drug response A Shukla, THM Nguyen, SB Moka, JJ Ellis, JP Grady, H Oey, AS Cristino, ... Nature communications 11 (1), 449, 2020 | 91 | 2020 |
Long noncoding RNAs CUPID1 and CUPID2 mediate breast cancer risk at 11q13 by modulating the response to DNA damage JA Betts, MM Marjaneh, F Al-Ejeh, YC Lim, W Shi, H Sivakumaran, ... The American Journal of Human Genetics 101 (2), 255-266, 2017 | 91 | 2017 |
Oncosis and apoptosis induction by activation of an overexpressed ion channel in breast cancer cells AA Peters, SYN Jamaludin, KTDS Yapa, S Chalmers, AP Wiegmans, ... Oncogene 36 (46), 6490-6500, 2017 | 79 | 2017 |
The calcium pump plasma membrane Ca2+-ATPase 2 (PMCA2) regulates breast cancer cell proliferation and sensitivity to doxorubicin AA Peters, MJG Milevskiy, WC Lee, MC Curry, CE Smart, JM Saunus, ... Scientific reports 6 (1), 25505, 2016 | 77 | 2016 |
In epithelial cancers, aberrant COL17A1 promoter methylation predicts its misexpression and increased invasion PU Thangavelu, T Krenács, E Dray, PHG Duijf Clinical epigenetics 8, 1-13, 2016 | 74 | 2016 |
NUCKS1 is a novel RAD51AP1 paralog important for homologous recombination and genome stability AC Parplys, W Zhao, N Sharma, T Groesser, F Liang, DG Maranon, ... Nucleic acids research 43 (20), 9817-9834, 2015 | 72 | 2015 |
Long-range regulators of the lncRNA HOTAIR enhance its prognostic potential in breast cancer MJG Milevskiy, F Al-Ejeh, JM Saunus, KS Northwood, PJ Bailey, JA Betts, ... Human molecular genetics 25 (15), 3269-3283, 2016 | 69 | 2016 |
PRMT2 and RORγ expression are associated with breast cancer survival outcomes TG Oh, P Bailey, E Dray, AG Smith, J Goode, N Eriksson, JW Funder, ... Molecular Endocrinology 28 (7), 1166-1185, 2014 | 60 | 2014 |
Molecular basis for enhancement of the meiotic DMC1 recombinase by RAD51 associated protein 1 (RAD51AP1) E Dray, MH Dunlop, L Kauppi, JS Filippo, C Wiese, MS Tsai, S Begovic, ... Proceedings of the National Academy of Sciences 108 (9), 3560-3565, 2011 | 51 | 2011 |
A variant of the breast cancer type 2 susceptibility protein (BRC) repeat is essential for the RECQL5 helicase to interact with RAD51 recombinase for genome stabilization MN Islam, N Paquet, D Fox, E Dray, XF Zheng, H Klein, P Sung, W Wang Journal of Biological Chemistry 287 (28), 23808-23818, 2012 | 50 | 2012 |
Mechanistic insights into RAD51-associated protein 1 (RAD51AP1) action in homologous DNA repair MH Dunlop, E Dray, W Zhao, J San Filippo, MS Tsai, SG Leung, D Schild, ... Journal of Biological Chemistry 287 (15), 12343-12347, 2012 | 49 | 2012 |
Overexpression of the E2F target gene CENPI promotes chromosome instability and predicts poor prognosis in estrogen receptor-positive breast cancer PU Thangavelu, CY Lin, S Vaidyanathan, THM Nguyen, E Dray, ... Oncotarget 8 (37), 62167, 2017 | 46 | 2017 |
Clinical use and mechanisms of resistance for PARP inhibitors in homologous recombination-deficient cancers DC Janysek, J Kim, PHG Duijf, E Dray Translational Oncology 14 (3), 101012, 2021 | 38 | 2021 |