Oxidized phospholipids on lipoprotein (a) elicit arterial wall inflammation and an inflammatory monocyte response in humans FM van der Valk, S Bekkering, J Kroon, C Yeang, J Van den Bossche, ... Circulation 134 (8), 611-624, 2016 | 513 | 2016 |
Lipoprotein (a) and oxidized phospholipids promote valve calcification in patients with aortic stenosis KH Zheng, S Tsimikas, T Pawade, J Kroon, WSA Jenkins, MK Doris, ... Journal of the American College of Cardiology 73 (17), 2150-2162, 2019 | 256 | 2019 |
PCSK9 monoclonal antibodies reverse the pro-inflammatory profile of monocytes in familial hypercholesterolaemia SJ Bernelot Moens, AE Neele, J Kroon, FM Van Der Valk, ... European heart journal 38 (20), 1584-1593, 2017 | 176 | 2017 |
A local VE-cadherin and Trio-based signaling complex stabilizes endothelial junctions through Rac1 I Timmerman, N Heemskerk, J Kroon, A Schaefer, J van Rijssel, ... Journal of cell science 128 (16), 3041-3054, 2015 | 127 | 2015 |
Atherogenic lipoprotein (a) increases vascular glycolysis, thereby facilitating inflammation and leukocyte extravasation JG Schnitzler, RM Hoogeveen, L Ali, KHM Prange, F Waissi, ... Circulation research 126 (10), 1346-1359, 2020 | 119 | 2020 |
Remnant cholesterol elicits arterial wall inflammation and a multilevel cellular immune response in humans SJ Bernelot Moens, SL Verweij, JG Schnitzler, LCA Stiekema, M Bos, ... Arteriosclerosis, thrombosis, and vascular biology 37 (5), 969-975, 2017 | 116 | 2017 |
Efficacy and safety assessment of a TRAF6-targeted nanoimmunotherapy in atherosclerotic mice and non-human primates M Lameijer, T Binderup, MMT Van Leent, ML Senders, F Fay, J Malkus, ... Nature biomedical engineering 2 (5), 279-292, 2018 | 115 | 2018 |
Triglyceride-rich lipoproteins and remnants: targets for therapy? GM Dallinga-Thie, J Kroon, J Borén, MJ Chapman Current cardiology reports 18, 1-9, 2016 | 109 | 2016 |
The Rho-guanine nucleotide exchange factor Trio controls leukocyte transendothelial migration by promoting docking structure formation J Van Rijssel, J Kroon, M Hoogenboezem, FPJ Van Alphen, RJ De Jong, ... Molecular biology of the cell 23 (15), 2831-2844, 2012 | 97 | 2012 |
Association of lipoprotein (a) with atherosclerotic plaque progression Y Kaiser, M Daghem, E Tzolos, MN Meah, MK Doris, AJ Moss, ... Journal of the American College of Cardiology 79 (3), 223-233, 2022 | 93 | 2022 |
Statin therapy and lipoprotein (a) levels: a systematic review and meta-analysis LM de Boer, AOJ Oorthuys, A Wiegman, MW Langendam, J Kroon, ... European journal of preventive cardiology 29 (5), 779-792, 2022 | 80 | 2022 |
Arterial and cellular inflammation in patients with CKD SJB Moens, SL Verweij, FM van der Valk, JC van Capelleveen, J Kroon, ... Journal of the American Society of Nephrology 28 (4), 1278-1285, 2017 | 76 | 2017 |
Tetraspanin CD63 promotes vascular endothelial growth factor receptor 2-β1 integrin complex formation, thereby regulating activation and downstream signaling in endothelial … S Tugues, S Honjo, C König, N Padhan, J Kroon, L Gualandi, X Li, ... Journal of Biological Chemistry 288 (26), 19060-19071, 2013 | 76 | 2013 |
Oral butyrate does not affect innate immunity and islet autoimmunity in individuals with longstanding type 1 diabetes: a randomised controlled trial PF de Groot, T Nikolic, S Imangaliyev, S Bekkering, G Duinkerken, ... Diabetologia 63, 597-610, 2020 | 74 | 2020 |
Targeted proteomics improves cardiovascular risk prediction in secondary prevention NS Nurmohamed, JP Belo Pereira, RM Hoogeveen, J Kroon, ... European heart journal 43 (16), 1569-1577, 2022 | 70 | 2022 |
Potent lipoprotein (a) lowering following apolipoprotein (a) antisense treatment reduces the pro-inflammatory activation of circulating monocytes in patients with elevated … LCA Stiekema, KHM Prange, RM Hoogeveen, SL Verweij, J Kroon, ... European heart journal 41 (24), 2262-2271, 2020 | 67 | 2020 |
Metabolism: the road to inflammation and atherosclerosis L Ali, JG Schnitzler, J Kroon Current Opinion in Lipidology 29 (6), 474-480, 2018 | 65 | 2018 |
Monocyte-chemoattractant protein-1 levels in human atherosclerotic lesions associate with plaque vulnerability MK Georgakis, SW Van Der Laan, Y Asare, JM Mekke, S Haitjema, ... Arteriosclerosis, thrombosis, and vascular biology 41 (6), 2038-2048, 2021 | 64 | 2021 |
PCSK9 antibody alirocumab attenuates arterial wall inflammation without changes in circulating inflammatory markers RM Hoogeveen, TSJ Opstal, Y Kaiser, LCA Stiekema, J Kroon, RJJ Knol, ... JACC: Cardiovascular Imaging 12 (12), 2571-2573, 2019 | 61 | 2019 |
Inhibition of GTPase Rac1 in endothelium by 6-mercaptopurine results in immunosuppression in nonimmune cells: new target for an old drug G Marinković, J Kroon, M Hoogenboezem, KA Hoeben, MS Ruiter, ... The Journal of Immunology 192 (9), 4370-4378, 2014 | 58 | 2014 |