CRISPR-Cas9 to induce fetal hemoglobin for the treatment of sickle cell disease S Demirci, A Leonard, K Essawi, JF Tisdale Molecular Therapy-Methods & Clinical Development 23, 276-285, 2021 | 38 | 2021 |
Definitive hematopoietic stem/progenitor cells from human embryonic stem cells through serum/feeder-free organoid-induced differentiation S Demirci, JJ Haro-Mora, A Leonard, C Drysdale, D Malide, K Keyvanfar, ... Stem cell research & therapy 11, 1-14, 2020 | 21 | 2020 |
Advances in CRISPR delivery methods: perspectives and challenges S Demirci, K Essawi, P Germino-Watnick, X Liu, W Hakami, JF Tisdale The CRISPR Journal 5 (5), 660-676, 2022 | 6 | 2022 |
Comparative Analysis of Red Blood Cells, White Blood Cells, Platelet Count, and Indices in Type 2 Diabetes Mellitus Patients and Normal Controls: Association and Clinical … K Essawi, G Dobie, MF Shaabi, W Hakami, M Saboor, AM Madkhali, ... Diabetes, Metabolic Syndrome and Obesity, 3123-3132, 2023 | 5 | 2023 |
Pre-existing immunity does not impair the engraftment of CRISPR-Cas9-edited cells in rhesus macaques conditioned with busulfan or radiation K Essawi, W Hakami, MBN Khan, R Martin, J Zeng, R Chu, N Uchida, ... Molecular Therapy Methods & Clinical Development 29, 483-493, 2023 | 4 | 2023 |
Forced enhancer-promoter rewiring to alter gene expression in animal models SA Peslak, S Demirci, V Chandra, B Ryu, SK Bhardwaj, J Jiang, ... Molecular Therapy-Nucleic Acids 31, 452-465, 2023 | 3 | 2023 |
Combined+ 58 and+ 55 BCL11A enhancer editing Yields exceptional efficiency, specificity and HbF induction in human and NHP preclinical models J Zeng, S Demirci, MA Nguyen, LY Lin, SA Maitland, E Mintzer, Y Wu, ... Blood 138, 1852, 2021 | 3 | 2021 |
In vivo measurement of RBC survival in patients with sickle cell disease before or after hematopoietic stem cell transplantation AK Leonard, D Furstenau, Z Inam, C Luckett, R Chu, S Demirci, K Essawi, ... Blood Advances 8 (7), 1806-1816, 2024 | 1 | 2024 |
Assessing Nutritional Anemia Among University Students in Jazan, Saudi Arabia: A Public Health Perspective W Hakami, G Dobie, KA Alneami, M Shaabi, K Essawi, M Saboor, ... Journal of Blood Medicine, 51-60, 2024 | | 2024 |
Impact of iron deficiency anemia on academic achievement among female university students in Saudi Arabia K Essawi, S Hakami, A Abdullah, D Badr, AA Madkhali, W Hakami, ... African journal of reproductive health 28 (9), 85-97, 2024 | | 2024 |
Ex vivo culture resting time impacts transplantation outcomes of genome-edited human hematopoietic stem and progenitor cells in xenograft mouse models S Demirci, MBN Khan, G Hinojosa, A Le, A Leonard, K Essawi, ... Cytotherapy 26 (6), 641-648, 2024 | | 2024 |
Correlation of circulating endothelial markers in COVID-19 patients admitted to the intensive care unit with laboratory data W Hakami, G Dobie, AA Mobarki, AM Madkhali, MS Akhter, AR Hakami, ... European Journal of Inflammation 21, 1721727X231210425, 2023 | | 2023 |
The Development of a Non-toxic Gene Editing Tool for the Study and Treatment of Sickle Cell Disease KM Essawi The Catholic University of America, 2022 | | 2022 |