| Perforin pores in the endosomal membrane trigger the release of endocytosed granzyme B into the cytosol of target cells J Thiery, D Keefe, S Boulant, E Boucrot, M Walch, D Martinvalet, ... Nature immunology 12 (8), 770-777, 2011 | 392 | 2011 |
| Alteration of the antitumor immune response by cancer-associated fibroblasts L Ziani, S Chouaib, J Thiery Frontiers in immunology 9, 414, 2018 | 353 | 2018 |
| Capture of microRNA–bound mRNAs identifies the tumor suppressor miR-34a as a regulator of growth factor signaling A Lal, MP Thomas, G Altschuler, F Navarro, E O'Day, XL Li, C Concepcion, ... PLoS genetics 7 (11), e1002363, 2011 | 285 | 2011 |
| Cytotoxic cells kill intracellular bacteria through granulysin-mediated delivery of granzymes M Walch, F Dotiwala, S Mulik, J Thiery, T Kirchhausen, C Clayberger, ... Cell 157 (6), 1309-1323, 2014 | 223 | 2014 |
| Perforin activates clathrin-and dynamin-dependent endocytosis, which is required for plasma membrane repair and delivery of granzyme B for granzyme-mediated apoptosis J Thiery, D Keefe, S Saffarian, D Martinvalet, M Walch, E Boucrot, ... Blood, The Journal of the American Society of Hematology 115 (8), 1582-1593, 2010 | 171 | 2010 |
| ITPR1 protects renal cancer cells against natural killer cells by inducing autophagy Y Messai, MZ Noman, M Hasmim, B Janji, A Tittarelli, M Boutet, V Baud, ... Cancer research 74 (23), 6820-6832, 2014 | 162 | 2014 |
| Critical role of tumor microenvironment in shaping NK cell functions: implication of hypoxic stress M Hasmim, Y Messai, L Ziani, J Thiery, JH Bouhris, MZ Noman, ... Frontiers in immunology 6, 482, 2015 | 144 | 2015 |
| Granzyme B-induced mitochondrial ROS are required for apoptosis G Jacquemin, D Margiotta, A Kasahara, EY Bassoy, M Walch, J Thiery, ... Cell Death & Differentiation 22 (5), 862-874, 2015 | 132 | 2015 |
| Melanoma-associated fibroblasts decrease tumor cell susceptibility to NK cell-mediated killing through matrix-metalloproteinases secretion L Ziani, TB Safta-Saadoun, J Gourbeix, A Cavalcanti, C Robert, G Favre, ... Oncotarget 8 (12), 19780, 2017 | 116 | 2017 |
| Arf-like GTPase Arl8b regulates lytic granule polarization and natural killer cell–mediated cytotoxicity A Tuli, J Thiery, AM James, X Michelet, M Sharma, S Garg, KB Sanborn, ... Molecular biology of the cell 24 (23), 3721-3735, 2013 | 77 | 2013 |
| Role of hypoxic stress in regulating tumor immunogenicity, resistance and plasticity S Terry, R Faouzi Zaarour, G Hassan Venkatesh, A Francis, W El-Sayed, ... International journal of molecular sciences 19 (10), 3044, 2018 | 74 | 2018 |
| Perforin: a key pore-forming protein for immune control of viruses and cancer J Thiery, J Lieberman MACPF/CDC Proteins-Agents of Defence, Attack and Invasion, 197-220, 2014 | 65 | 2014 |
| Granzyme B–activated p53 interacts with Bcl-2 to promote cytotoxic lymphocyte–mediated apoptosis T Ben Safta, L Ziani, L Favre, L Lamendour, G Gros, F Mami-Chouaib, ... The Journal of Immunology 194 (1), 418-428, 2015 | 62 | 2015 |
| A three-dimensional tumor cell defect in activating autologous CTLs is associated with inefficient antigen presentation correlated with heat shock protein-70 down-regulation V Dangles-Marie, S Richon, M El Behi, H Echchakir, G Dorothée, J Thiery, ... Cancer research 63 (13), 3682-3687, 2003 | 60 | 2003 |
| Role of hypoxia-mediated autophagy in tumor cell death and survival RF Zaarour, B Azakir, EY Hajam, H Nawafleh, NA Zeinelabdin, ... Cancers 13 (3), 533, 2021 | 55 | 2021 |
| Tumor escape from killing: role of killer inhibitory receptors and acquisition of tumor resistance to cell death S Chouaib, J Thiery, A Gati, N Guerra, M El Behi, G Dorothee, ... Tissue Antigens 60 (4), 273-281, 2002 | 50 | 2002 |
| The pharmalogical reactivation of p53 function improves breast tumor cell lysis by granzyme B and NK cells through induction of autophagy M Chollat-Namy, T Ben Safta-Saadoun, D Haferssas, G Meurice, ... Cell death & disease 10 (10), 695, 2019 | 49 | 2019 |
| Hypoxia increases melanoma-associated fibroblasts immunosuppressive potential and inhibitory effect on T cell-mediated cytotoxicity L Ziani, S Buart, S Chouaib, J Thiery Oncoimmunology 10 (1), 1950953, 2021 | 47 | 2021 |
| Isolation of cytotoxic T cell and NK granules and purification of their effector proteins J Thiery, M Walch, DK Jensen, D Martinvalet, J Lieberman Current protocols in cell biology 47 (1), 3.37. 1-3.37. 29, 2010 | 47 | 2010 |
| Granzyme B-induced cell death involves induction of p53 tumor suppressor gene and its activation in tumor target cells F Meslin, J Thiery, C Richon, A Jalil, S Chouaib Journal of Biological Chemistry 282 (45), 32991-32999, 2007 | 47 | 2007 |
