Lactate: a metabolic driver in the tumour landscape L Ippolito, A Morandi, E Giannoni, P Chiarugi Trends in biochemical sciences 44 (2), 153-166, 2019 | 337 | 2019 |
Cancer-associated fibroblasts promote prostate cancer malignancy via metabolic rewiring and mitochondrial transfer L Ippolito, A Morandi, ML Taddei, M Parri, G Comito, A Iscaro, ... Oncogene 38 (27), 5339-5355, 2019 | 201 | 2019 |
Compartmentalized activities of the pyruvate dehydrogenase complex sustain lipogenesis in prostate cancer J Chen, I Guccini, D Di Mitri, D Brina, A Revandkar, M Sarti, E Pasquini, ... Nature genetics 50 (2), 219-228, 2018 | 181 | 2018 |
Targeting the receptor tyrosine kinase RET sensitizes breast cancer cells to tamoxifen treatment and reveals a role for RET in endocrine resistance I Plaza-Menacho, A Morandi, D Robertson, S Pancholi, S Drury, ... Oncogene 29 (33), 4648-4657, 2010 | 167 | 2010 |
Lactate modulates CD4+ T-cell polarization and induces an immunosuppressive environment, which sustains prostate carcinoma progression via TLR8/miR21 axis G Comito, A Iscaro, M Bacci, A Morandi, L Ippolito, M Parri, I Montagnani, ... Oncogene 38 (19), 3681-3695, 2019 | 166 | 2019 |
Linking metabolic reprogramming to therapy resistance in cancer A Morandi, S Indraccolo Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1868 (1), 1-6, 2017 | 152 | 2017 |
Senescent stroma promotes prostate cancer progression: the role of miR-210 ML Taddei, L Cavallini, G Comito, E Giannoni, M Folini, A Marini, ... Molecular oncology 8 (8), 1729-1746, 2014 | 138 | 2014 |
Targeting the metabolic reprogramming that controls epithelial-to-mesenchymal transition in aggressive tumors A Morandi, ML Taddei, P Chiarugi, E Giannoni Frontiers in oncology 7, 40, 2017 | 137 | 2017 |
Metabolic shift toward oxidative phosphorylation in docetaxel resistant prostate cancer cells L Ippolito, A Marini, L Cavallini, A Morandi, L Pietrovito, G Pintus, ... Oncotarget 7 (38), 61890, 2016 | 134 | 2016 |
GDNF–RET signaling in ER-positive breast cancers is a key determinant of response and resistance to aromatase inhibitors A Morandi, LA Martin, Q Gao, S Pancholi, A Mackay, D Robertson, ... Cancer research 73 (12), 3783-3795, 2013 | 131 | 2013 |
Ponatinib is a potent inhibitor of wild-type and drug-resistant gatekeeper mutant RET kinase L Mologni, S Redaelli, A Morandi, I Plaza-Menacho, ... Molecular and cellular endocrinology 377 (1-2), 1-6, 2013 | 112 | 2013 |
Mesenchymal to amoeboid transition is associated with stem-like features of melanoma cells ML Taddei, E Giannoni, A Morandi, L Ippolito, M Ramazzotti, M Callari, ... Cell Communication and Signaling 12, 1-12, 2014 | 109 | 2014 |
RET in breast cancer: functional and therapeutic implications A Morandi, I Plaza-Menacho, CM Isacke Trends in molecular medicine 17 (3), 149-157, 2011 | 109 | 2011 |
Targeting stromal-induced pyruvate kinase M2 nuclear translocation impairs oxphos and prostate cancer metastatic spread E Giannoni, ML Taddei, A Morandi, G Comito, M Calvani, F Bianchini, ... Oncotarget 6 (27), 24061, 2015 | 105 | 2015 |
Fat and furious: lipid metabolism in antitumoral therapy response and resistance M Bacci, N Lorito, A Smiriglia, A Morandi Trends in cancer 7 (3), 198-213, 2021 | 96 | 2021 |
miR-155 Drives Metabolic Reprogramming of ER+ Breast Cancer Cells Following Long-Term Estrogen Deprivation and Predicts Clinical Response to Aromatase … M Bacci, E Giannoni, A Fearns, R Ribas, Q Gao, ML Taddei, G Pintus, ... Cancer research 76 (6), 1615-1626, 2016 | 94 | 2016 |
Metabolic reprogramming identifies the most aggressive lesions at early phases of hepatic carcinogenesis MA Kowalik, G Guzzo, A Morandi, A Perra, S Menegon, I Masgras, ... Oncotarget 7 (22), 32375, 2016 | 92 | 2016 |
Reprogramming of amino acid transporters to support aspartate and glutamate dependency sustains endocrine resistance in breast cancer M Bacci, N Lorito, L Ippolito, M Ramazzotti, S Luti, S Romagnoli, M Parri, ... Cell reports 28 (1), 104-118. e8, 2019 | 80 | 2019 |
ERK5/BMK1 is indispensable for optimal colony-stimulating factor 1 (CSF-1)-induced proliferation in macrophages in a Src-dependent fashion E Rovida, E Spinelli, S Sdelci, V Barbetti, A Morandi, S Giuntoli, ... The Journal of Immunology 180 (6), 4166-4172, 2008 | 77 | 2008 |
Lactate rewires lipid metabolism and sustains a metabolic–epigenetic axis in prostate cancer L Ippolito, G Comito, M Parri, M Iozzo, A Duatti, F Virgilio, N Lorito, ... Cancer research 82 (7), 1267-1282, 2022 | 69 | 2022 |