The roles of co-transmission in neural network modulation MP Nusbaum, DM Blitz, AM Swensen, D Wood, E Marder Trends in neurosciences 24 (3), 146-154, 2001 | 392 | 2001 |
Ionic mechanisms of burst firing in dissociated Purkinje neurons AM Swensen, BP Bean Journal of Neuroscience 23 (29), 9650-9663, 2003 | 248 | 2003 |
Robustness of burst firing in dissociated purkinje neurons with acute or long-term reductions in sodium conductance AM Swensen, BP Bean Journal of Neuroscience 25 (14), 3509-3520, 2005 | 230 | 2005 |
Multiple peptides converge to activate the same voltage-dependent current in a central pattern-generating circuit AM Swensen, E Marder Journal of Neuroscience 20 (18), 6752-6759, 2000 | 221 | 2000 |
eIF2B activator prevents neurological defects caused by a chronic integrated stress response YL Wong, L LeBon, AM Basso, KL Kohlhaas, AL Nikkel, HM Robb, ... Elife 8, e42940, 2019 | 176 | 2019 |
Modulators with convergent cellular actions elicit distinct circuit outputs AM Swensen, E Marder Journal of Neuroscience 21 (11), 4050-4058, 2001 | 159 | 2001 |
Analgesic effects of a substituted N-triazole oxindole (TROX-1), a state-dependent, voltage-gated calcium channel 2 blocker C Abbadie, OB McManus, SY Sun, RM Bugianesi, G Dai, RJ Haedo, ... Journal of Pharmacology and Experimental Therapeutics 334 (2), 545-555, 2010 | 117 | 2010 |
A high-throughput assay for evaluating state dependence and subtype selectivity of Cav2 calcium channel inhibitors G Dai, RJ Haedo, VA Warren, KS Ratliff, RM Bugianesi, A Rush, ... Assay and drug development technologies 6 (2), 195-212, 2008 | 100 | 2008 |
Gaba and Responses to Gaba in the Stomatogastric Ganglion of the Crab Cancer Borealis AM Swensen, J Golowasch, AE Christie, MJ Coleman, MP Nusbaum, ... Journal of Experimental Biology 203 (14), 2075-2092, 2000 | 88 | 2000 |
Characterization of the substituted N-triazole oxindole TROX-1, a small-molecule, state-dependent inhibitor of Cav2 calcium channels AM Swensen, J Herrington, RM Bugianesi, G Dai, RJ Haedo, KS Ratliff, ... Molecular pharmacology 81 (3), 488-497, 2012 | 75 | 2012 |
Discovery of 4-[(2R,4R)-4-({[1-(2,2-Difluoro-1,3-benzodioxol-5-yl)cyclopropyl]carbonyl}amino)-7-(difluoromethoxy)-3,4-dihydro-2H-chromen-2-yl]benzoic Acid … X Wang, B Liu, X Searle, C Yeung, A Bogdan, S Greszler, A Singh, Y Fan, ... Journal of Medicinal Chemistry 61 (4), 1436-1449, 2018 | 74 | 2018 |
Automated electrophysiology in drug discovery BT Priest, AM Swensen, OB McManus Current pharmaceutical design 13 (23), 2325-2337, 2007 | 62 | 2007 |
Novel CaV2.1 clone replicates many properties of Purkinje cell CaV2.1 current KS Richards, AM Swensen, D Lipscombe, K Bommert European Journal of Neuroscience 26 (10), 2950-2961, 2007 | 44 | 2007 |
A-1048400 is a novel, orally active, state-dependent neuronal calcium channel blocker that produces dose-dependent antinociception without altering hemodynamic function in rats VE Scott, TA Vortherms, W Niforatos, AM Swensen, T Neelands, I Milicic, ... Biochemical pharmacology 83 (3), 406-418, 2012 | 40 | 2012 |
A Pharmacologically Validated, High-Capacity, Functional Thallium Flux Assay for the Human Ether-à-go-go Related Gene Potassium Channel WA Schmalhofer, AM Swensen, BS Thomas, JP Felix, RJ Haedo, K Solly, ... Assay and drug development technologies 8 (6), 714-726, 2010 | 40 | 2010 |
Identification and characterization of novel CFTR potentiators M Gees, S Musch, S Van der Plas, AS Wesse, A Vandevelde, K Verdonck, ... Frontiers in pharmacology 9, 1221, 2018 | 39 | 2018 |
Pharmacologic inhibition of the renal outer medullary potassium channel causes diuresis and natriuresis in the absence of kaliuresis J Pharmacol Exp Ther. 348 (1), 153-164, 2014 | 37 | 2014 |
Discovery of ABBV/GLPG-3221, a Potent Corrector of CFTR for the Treatment of Cystic Fibrosis MJC Scanio, XB Searle, B Liu, JR Koenig, R Altenbach, GA Gfesser, ... ACS Medicinal Chemistry Letters 10 (11), 1543-1548, 2019 | 33 | 2019 |
Discovery of MK-7145, an oral small molecule ROMK inhibitor for the treatment of hypertension and heart failure H Tang, Y Zhu, N Teumelsan, SP Walsh, A Shahripour, BT Priest, ... ACS Medicinal Chemistry Letters 7 (7), 697-701, 2016 | 33 | 2016 |
Aminopiperidine Sulfonamide Cav2.2 Channel Inhibitors for the Treatment of Chronic Pain PP Shao, F Ye, PK Chakravarty, DJ Varughese, JB Herrington, G Dai, ... Journal of medicinal chemistry 55 (22), 9847-9855, 2012 | 33 | 2012 |