关注
ANDREW SWENSEN
ANDREW SWENSEN
Principal Research Scientist, AbbVie Inc.
在 ABBVIE.COM 的电子邮件经过验证
标题
引用次数
引用次数
年份
The roles of co-transmission in neural network modulation
MP Nusbaum, DM Blitz, AM Swensen, D Wood, E Marder
Trends in neurosciences 24 (3), 146-154, 2001
3922001
Ionic mechanisms of burst firing in dissociated Purkinje neurons
AM Swensen, BP Bean
Journal of Neuroscience 23 (29), 9650-9663, 2003
2482003
Robustness of burst firing in dissociated purkinje neurons with acute or long-term reductions in sodium conductance
AM Swensen, BP Bean
Journal of Neuroscience 25 (14), 3509-3520, 2005
2302005
Multiple peptides converge to activate the same voltage-dependent current in a central pattern-generating circuit
AM Swensen, E Marder
Journal of Neuroscience 20 (18), 6752-6759, 2000
2212000
eIF2B activator prevents neurological defects caused by a chronic integrated stress response
YL Wong, L LeBon, AM Basso, KL Kohlhaas, AL Nikkel, HM Robb, ...
Elife 8, e42940, 2019
1762019
Modulators with convergent cellular actions elicit distinct circuit outputs
AM Swensen, E Marder
Journal of Neuroscience 21 (11), 4050-4058, 2001
1592001
Analgesic effects of a substituted N-triazole oxindole (TROX-1), a state-dependent, voltage-gated calcium channel 2 blocker
C Abbadie, OB McManus, SY Sun, RM Bugianesi, G Dai, RJ Haedo, ...
Journal of Pharmacology and Experimental Therapeutics 334 (2), 545-555, 2010
1172010
A high-throughput assay for evaluating state dependence and subtype selectivity of Cav2 calcium channel inhibitors
G Dai, RJ Haedo, VA Warren, KS Ratliff, RM Bugianesi, A Rush, ...
Assay and drug development technologies 6 (2), 195-212, 2008
1002008
Gaba and Responses to Gaba in the Stomatogastric Ganglion of the Crab Cancer Borealis
AM Swensen, J Golowasch, AE Christie, MJ Coleman, MP Nusbaum, ...
Journal of Experimental Biology 203 (14), 2075-2092, 2000
882000
Characterization of the substituted N-triazole oxindole TROX-1, a small-molecule, state-dependent inhibitor of Cav2 calcium channels
AM Swensen, J Herrington, RM Bugianesi, G Dai, RJ Haedo, KS Ratliff, ...
Molecular pharmacology 81 (3), 488-497, 2012
752012
Discovery of 4-[(2R,4R)-4-({[1-(2,2-Difluoro-1,3-benzodioxol-5-yl)cyclopropyl]carbonyl}amino)-7-(difluoromethoxy)-3,4-dihydro-2H-chromen-2-yl]benzoic Acid …
X Wang, B Liu, X Searle, C Yeung, A Bogdan, S Greszler, A Singh, Y Fan, ...
Journal of Medicinal Chemistry 61 (4), 1436-1449, 2018
742018
Automated electrophysiology in drug discovery
BT Priest, AM Swensen, OB McManus
Current pharmaceutical design 13 (23), 2325-2337, 2007
622007
Novel CaV2.1 clone replicates many properties of Purkinje cell CaV2.1 current
KS Richards, AM Swensen, D Lipscombe, K Bommert
European Journal of Neuroscience 26 (10), 2950-2961, 2007
442007
A-1048400 is a novel, orally active, state-dependent neuronal calcium channel blocker that produces dose-dependent antinociception without altering hemodynamic function in rats
VE Scott, TA Vortherms, W Niforatos, AM Swensen, T Neelands, I Milicic, ...
Biochemical pharmacology 83 (3), 406-418, 2012
402012
A Pharmacologically Validated, High-Capacity, Functional Thallium Flux Assay for the Human Ether-à-go-go Related Gene Potassium Channel
WA Schmalhofer, AM Swensen, BS Thomas, JP Felix, RJ Haedo, K Solly, ...
Assay and drug development technologies 8 (6), 714-726, 2010
402010
Identification and characterization of novel CFTR potentiators
M Gees, S Musch, S Van der Plas, AS Wesse, A Vandevelde, K Verdonck, ...
Frontiers in pharmacology 9, 1221, 2018
392018
Pharmacologic inhibition of the renal outer medullary potassium channel causes diuresis and natriuresis in the absence of kaliuresis
J Pharmacol Exp Ther. 348 (1), 153-164, 2014
372014
Discovery of ABBV/GLPG-3221, a Potent Corrector of CFTR for the Treatment of Cystic Fibrosis
MJC Scanio, XB Searle, B Liu, JR Koenig, R Altenbach, GA Gfesser, ...
ACS Medicinal Chemistry Letters 10 (11), 1543-1548, 2019
332019
Discovery of MK-7145, an oral small molecule ROMK inhibitor for the treatment of hypertension and heart failure
H Tang, Y Zhu, N Teumelsan, SP Walsh, A Shahripour, BT Priest, ...
ACS Medicinal Chemistry Letters 7 (7), 697-701, 2016
332016
Aminopiperidine Sulfonamide Cav2.2 Channel Inhibitors for the Treatment of Chronic Pain
PP Shao, F Ye, PK Chakravarty, DJ Varughese, JB Herrington, G Dai, ...
Journal of medicinal chemistry 55 (22), 9847-9855, 2012
332012
系统目前无法执行此操作,请稍后再试。
文章 1–20