| A novel tumor necrosis factor–mediated mechanism of direct epithelial sodium channel activation I Czikora, A Alli, HF Bao, D Kaftan, S Sridhar, HJ Apell, B Gorshkov, ... American journal of respiratory and critical care medicine 190 (5), 522-532, 2014 | 68 | 2014 |
| The PI3 kinase/mTOR blocker NVP-BEZ235 overrides resistance against irreversible ErbB inhibitors in breast cancer cells C Brünner-Kubath, W Shabbir, V Saferding, R Wagner, CF Singer, ... Breast cancer research and treatment 129, 387-400, 2011 | 68 | 2011 |
| A C-terminal membrane anchor affects the interactions of prion proteins with lipid membranes NK Chu, W Shabbir, E Bove-Fenderson, C Araman, R Lemmens-Gruber, ... Journal of Biological Chemistry 289 (43), 30144-30160, 2014 | 36 | 2014 |
| Mechanism of action of novel lung edema therapeutic AP301 by activation of the epithelial sodium channel W Shabbir, P Scherbaum-Hazemi, S Tzotzos, B Fischer, H Fischer, ... Molecular pharmacology 84 (6), 899-910, 2013 | 36 | 2013 |
| AP301, a synthetic peptide mimicking the lectin-like domain of TNF, enhances amiloride-sensitive Na+ current in primary dog, pig and rat alveolar type II cells S Tzotzos, B Fischer, H Fischer, H Pietschmann, R Lucas, G Dupré, ... Pulmonary pharmacology & therapeutics 26 (3), 356-363, 2013 | 32 | 2013 |
| Curcumin potentiates α7 nicotinic acetylcholine receptors and alleviates autistic-like social deficits and brain oxidative stress status in mice P Jayaprakash, D Isaev, W Shabbir, DE Lorke, B Sadek, M Oz International journal of molecular sciences 22 (14), 7251, 2021 | 22 | 2021 |
| The lectin-like domain of TNF increases ENaC open probability through a novel site at the interface between the second transmembrane and C-terminal domains of the α-subunit R Lucas, Q Yue, A Alli, BJ Duke, O Al-Khalili, TL Thai, J Hamacher, ... Journal of Biological Chemistry 291 (45), 23440-23451, 2016 | 21 | 2016 |
| Cannabidiol inhibits multiple ion channels in rabbit ventricular cardiomyocytes D Isaev, W Shabbir, EY Dinc, DE Lorke, G Petroianu, M Oz Frontiers in pharmacology 13, 821758, 2022 | 20 | 2022 |
| Glycosylation-dependent activation of epithelial sodium channel by solnatide W Shabbir, S Tzotzos, M Bedak, M Aufy, A Willam, M Kraihammer, ... Biochemical Pharmacology 98 (4), 740-753, 2015 | 20 | 2015 |
| Restoration of epithelial sodium channel function by synthetic peptides in pseudohypoaldosteronism type 1B mutants A Willam, M Aufy, S Tzotzos, H Evanzin, S Chytracek, S Geppert, ... Frontiers in Pharmacology 8, 85, 2017 | 17 | 2017 |
| WNK1 is a chloride-stimulated scaffold that regulates mTORC2 activity and ion transport B Saha, DCA Leite-Dellova, J Demko, MV Sørensen, E Takagi, ... Journal of cell science 135 (23), jcs260313, 2022 | 16 | 2022 |
| Interaction of diltiazem with an intracellularly accessible binding site on CaV1.2 W Shabbir, S Beyl, EN Timin, D Schellmann, T Erker, A Hohaus, ... British journal of pharmacology 162 (5), 1074-1082, 2011 | 16 | 2011 |
| TnF lectin-like Domain restores epithelial sodium channel Function in Frameshift Mutants associated with Pseudohypoaldosteronism Type 1B A Willam, M Aufy, S Tzotzos, D El-Malazi, F Poser, A Wagner, ... Frontiers in immunology 8, 601, 2017 | 14 | 2017 |
| Potassium activates mTORC2-dependent SGK1 phosphorylation to stimulate epithelial sodium channel: role in rapid renal responses to dietary potassium B Saha, W Shabbir, E Takagi, XP Duan, DCAL Dellova, J Demko, A Manis, ... Journal of the American Society of Nephrology 34 (6), 1019-1038, 2023 | 10 | 2023 |
| CRISPR/Cas9 Mediated Knock Down of δ-ENaC Blunted the TNF-Induced Activation of ENaC in A549 Cells W Shabbir, N Topcagic, M Aufy, M Oz International Journal of Molecular Sciences 22 (4), 1858, 2021 | 9 | 2021 |
| Loss of barrier integrity in alveolar epithelial cells downregulates ENaC expression and activity via Ca2+ and TRPV4 activation A Dagenais, J Desjardins, W Shabbir, A Roy, D Filion, R Sauvé, ... Pflügers Archiv-European Journal of Physiology 470, 1615-1631, 2018 | 9 | 2018 |
| Identification of phosphorylation sites and binding pockets for modulation of NaV1.5 channel by Fyn tyrosine kinase SM Iqbal, M Aufy, W Shabbir, R Lemmens‐Gruber The FEBS Journal 285 (13), 2520-2530, 2018 | 9 | 2018 |
| Physicochemical properties of pore residues predict activation gating of CaV1.2: A correlation mutation analysis S Beyl, K Depil, A Hohaus, A Stary-Weinzinger, E Timin, W Shabbir, ... Pflügers Archiv-European Journal of Physiology 461, 53-63, 2011 | 9 | 2011 |
| Potassium activates mTORC2-dependent SGK1 phosphorylation to stimulate ENaC: role in rapid renal responses to dietary potassium B Saha, W Shabbir, E Takagi, XP Duan, DC Almeida Leite Dellova, ... Journal of the American Society of Nephrology (JASN) 34 (6), 1019-1038, 2023 | 6 | 2023 |
| Activation of autosomal recessive Pseudohypoaldosteronism1 ENaC with aldosterone W Shabbir, N Topcagic, M Aufy European Journal of Pharmacology 901, 174090, 2021 | 6 | 2021 |
