The epitranscriptome m6A writer METTL3 promotes chemo-and radioresistance in pancreatic cancer cells K Taketo, M Konno, A Asai, J Koseki, M Toratani, T Satoh, Y Doki, M Mori, ... International journal of oncology 52 (2), 621-629, 2018 | 347 | 2018 |
Oncogene c-Myc promotes epitranscriptome m6A reader YTHDF1 expression in colorectal cancer Y Nishizawa, M Konno, A Asai, J Koseki, K Kawamoto, N Miyoshi, ... Oncotarget 9 (7), 7476, 2018 | 213 | 2018 |
Role of pyruvate kinase M2 in transcriptional regulation leading to epithelial–mesenchymal transition A Hamabe, M Konno, N Tanuma, H Shima, K Tsunekuni, K Kawamoto, ... Proceedings of the National Academy of Sciences 111 (43), 15526-15531, 2014 | 210 | 2014 |
Tumour-suppressive function of SIRT4 in human colorectal cancer M Miyo, H Yamamoto, M Konno, H Colvin, N Nishida, J Koseki, ... British journal of cancer 113 (3), 492-499, 2015 | 155 | 2015 |
MicroRNA-1246 expression associated with CCNG2-mediated chemoresistance and stemness in pancreatic cancer S Hasegawa, H Eguchi, H Nagano, M Konno, Y Tomimaru, H Wada, ... British journal of cancer 111 (8), 1572-1580, 2014 | 151 | 2014 |
Distinct methylation levels of mature microRNAs in gastrointestinal cancers M Konno, J Koseki, A Asai, A Yamagata, T Shimamura, D Motooka, ... Nature communications 10 (1), 3888, 2019 | 147 | 2019 |
Oncometabolite D-2-hydroxyglurate directly induces epithelial-mesenchymal transition and is associated with distant metastasis in colorectal cancer H Colvin, N Nishida, M Konno, N Haraguchi, H Takahashi, J Nishimura, ... Scientific reports 6 (1), 36289, 2016 | 117 | 2016 |
α-1-C-Butyl-1,4-dideoxy-1,4-imino-l-arabinitol as a Second-Generation Iminosugar-Based Oral α-Glucosidase Inhibitor for Improving Postprandial Hyperglycemia A Kato, E Hayashi, S Miyauchi, I Adachi, T Imahori, Y Natori, Y Yoshimura, ... Journal of medicinal chemistry 55 (23), 10347-10362, 2012 | 86 | 2012 |
Metabolic adaptation to nutritional stress in human colorectal cancer M Miyo, M Konno, N Nishida, T Sueda, K Noguchi, H Matsui, H Colvin, ... Scientific reports 6 (1), 38415, 2016 | 71 | 2016 |
The combination of the expression of hexokinase 2 and pyruvate kinase M2 is a prognostic marker in patients with pancreatic cancer H Ogawa, H Nagano, M Konno, H Eguchi, J Koseki, K Kawamoto, ... Molecular and clinical oncology 3 (3), 563-571, 2015 | 65 | 2015 |
CD44/CD133-positive colorectal cancer stem cells are sensitive to trifluridine exposure K Tsunekuni, M Konno, N Haraguchi, J Koseki, A Asai, K Matsuoka, ... Scientific reports 9 (1), 14861, 2019 | 60 | 2019 |
The mitochondrial one‑carbon metabolic pathway is associated with patient survival in pancreatic cancer K Noguchi, M Konno, J Koseki, N Nishida, K Kawamoto, D Yamada, ... Oncology letters 16 (2), 1827-1834, 2018 | 55 | 2018 |
The importance of mitochondrial folate enzymes in human colorectal cancer M Miyo, M Konno, H Colvin, N Nishida, J Koseki, K Kawamoto, ... Oncology reports 37 (1), 417-425, 2017 | 55 | 2017 |
Disruption of endolysosomal RAB5/7 efficiently eliminates colorectal cancer stem cells M Takeda, J Koseki, H Takahashi, N Miyoshi, N Nishida, J Nishimura, ... Cancer research 79 (7), 1426-1437, 2019 | 54 | 2019 |
Enzymes of the one-carbon folate metabolism as anticancer targets predicted by survival rate analysis J Koseki, M Konno, A Asai, H Colvin, K Kawamoto, N Nishida, D Sakai, ... Scientific reports 8 (1), 303, 2018 | 51 | 2018 |
Design and synthesis of labystegines, hybrid iminosugars from LAB and calystegine, as inhibitors of intestinal α-glucosidases: binding conformation and interaction for ntSI A Kato, ZL Zhang, HY Wang, YM Jia, CY Yu, K Kinami, Y Hirokami, Y Tsuji, ... The Journal of organic chemistry 80 (9), 4501-4515, 2015 | 49 | 2015 |
MicroRNAs induce epigenetic reprogramming and suppress malignant phenotypes of human colon cancer cells H Ogawa, X Wu, K Kawamoto, N Nishida, M Konno, J Koseki, H Matsui, ... PLoS One 10 (5), e0127119, 2015 | 44 | 2015 |
Spatial and single-cell transcriptomics decipher the cellular environment containing HLA-G+ cancer cells and SPP1+ macrophages in colorectal cancer Y Ozato, Y Kojima, Y Kobayashi, Y Hisamatsu, T Toshima, Y Yonemura, ... Cell reports 42 (1), 2023 | 41 | 2023 |
Combined evaluation of hexokinase 2 and phosphorylated pyruvate dehydrogenase‐E1α in invasive front lesions of colorectal tumors predicts cancer metabolism and patient prognosis A Hamabe, H Yamamoto, M Konno, M Uemura, J Nishimura, T Hata, ... Cancer science 105 (9), 1100-1108, 2014 | 41 | 2014 |
Mitochondrial pyruvate carrier 1 expression controls cancer epithelial‐mesenchymal transition and radioresistance Y Takaoka, M Konno, J Koseki, H Colvin, A Asai, K Tamari, T Satoh, ... Cancer Science 110 (4), 1331-1339, 2019 | 39 | 2019 |