Drug repurposing screens reveal cell-type-specific entry pathways and FDA-approved drugs active against SARS-Cov-2 M Dittmar, JS Lee, K Whig, E Segrist, M Li, B Kamalia, L Castellana, ... Cell reports 35 (1), 2021 | 185 | 2021 |
Pharmacological activation of STING blocks SARS-CoV-2 infection M Li, M Ferretti, B Ying, H Descamps, E Lee, M Dittmar, JS Lee, K Whig, ... Science immunology 6 (59), eabi9007, 2021 | 161 | 2021 |
Pyrimidine inhibitors synergize with nucleoside analogues to block SARS-CoV-2 DC Schultz, RM Johnson, K Ayyanathan, J Miller, K Whig, B Kamalia, ... Nature 604 (7904), 134-140, 2022 | 159 | 2022 |
Drug repurposing screens reveal FDA approved drugs active against SARS-Cov-2 M Dittmar, JS Lee, K Whig, E Segrist, M Li, K Jurado, K Samby, H Ramage, ... biorxiv, 2020.06. 19.161042, 2020 | 59 | 2020 |
Modulation of BCL-2 in both T cells and tumor cells to enhance chimeric antigen receptor T-cell immunotherapy against cancer YG Lee, P Guruprasad, G Ghilardi, R Pajarillo, CT Sauter, R Patel, ... Cancer discovery 12 (10), 2372-2391, 2022 | 47 | 2022 |
High-throughput identification of post-transcriptional utrophin up-regulators for Duchenne muscle dystrophy (DMD) therapy E Loro, K Sengupta, S Bogdanovich, K Whig, DC Schultz, DM Huryn, ... Scientific Reports 10 (1), 2132, 2020 | 28 | 2020 |
Discovery of novel small-molecule inducers of heme oxygenase-1 that protect human iPSC-derived cardiomyocytes from oxidative stress RJ Kirby, DB Divlianska, K Whig, N Bryan, CJ Morfa, A Koo, BL Hood, ... Journal of Pharmacology and Experimental Therapeutics 364 (1), 87-96, 2018 | 27 | 2018 |
Drug repurposing screens reveal cell-type-specific entry pathways and FDA-approved drugs active against SARS-Cov-2. Cell Rep 35: 108959 M Dittmar, JS Lee, K Whig, E Segrist, M Li, B Kamalia, L Castellana, ... | 19 | 2021 |
Discovery of small molecule guanylyl cyclase A receptor positive allosteric modulators SJ Sangaralingham, K Whig, S Peddibhotla, RJ Kirby, HE Sessions, ... Proceedings of the National Academy of Sciences 118 (52), e2109386118, 2021 | 17 | 2021 |
Pharmacological activation of STING blocks SARS-CoV-2 infection. Sci Immunol 6: eabi9007 M Li, M Ferretti, B Ying, H Descamps, E Lee, M Dittmar, JS Lee, K Whig, ... | 16 | 2021 |
The lncRNA ALPHA specifically targets chikungunya virus to control infection MG Basavappa, M Ferretti, M Dittmar, J Stoute, MC Sullivan, K Whig, ... Molecular cell 82 (19), 3729-3744. e10, 2022 | 10 | 2022 |
Modulation of BCL-2 in both T cells and tumor cells to enhance chimeric antigen receptor T-cell immunotherapy against cancer. Cancer Discov 2022; 12: 2372–91. doi: 10.1158/2159 … YG Lee, P Guruprasad, G Ghilardi, R Pajarillo, CT Sauter, R Patel, ... CD-21-1026, 0 | 10 | |
High-throughput RNA interference screening: Tricks of the trade NM Nebane, T Coric, K Whig, S McKellip, LK Woods, M Sosa, ... Journal of laboratory automation 18 (4), 334-339, 2013 | 9 | 2013 |
Acoustic droplet ejection technology and its application in high-throughput RNA interference screening NM Nebane, T Coric, S McKellip, LK Woods, M Sosa, L Rasmussen, ... Journal of laboratory automation 21 (1), 198-203, 2016 | 7 | 2016 |
Pyrimidine biosynthesis inhibitors synergize with nucleoside analogs to block SARS-CoV-2 infection DC Schultz, RM Johnson, K Ayyanathan, J Miller, K Whig, B Kamalia, ... bioRxiv, 2021.06. 24.449811, 2021 | 6 | 2021 |
Drug repurposing screens reveal cell-typespecific entry pathways and FDA-approved drugs active against SARS-Cov-2. Cell Rep. 2021; 35 (1): 108959 M Dittmar, JS Lee, K Whig, E Segrist, M Li, B Kamalia J. CELREP, 2021 | 6 | 2021 |
Development and application of high-throughput screens for the discovery of compounds that disrupt ErbB4 signaling: Candidate cancer therapeutics RL Cullum, LM Lucas, JI Senfeld, JT Piazza, LT Neel, K Whig, L Zhai, ... Plos one 15 (12), e0243901, 2020 | 5 | 2020 |
Polo-like kinase 1 as a therapeutic target for malignant peripheral nerve sheath tumors (MPNST) and schwannomas J Guo, KE Chaney, K Choi, G Witek, AV Patel, H Xie, D Lin, K Whig, ... American Journal of Cancer Research 10 (3), 856, 2020 | 5 | 2020 |
Drug repurposing screens reveal FDA approved drugs active against SARS-Cov-2. bioRxiv. 2020 M Dittmar, JS Lee, K Whig, E Segrist, M Li, K Jurado, K Samby, H Ramage, ... Google Scholar, 0 | 5 | |
Nucleoside analogs NM107 and AT-527 are antiviral against rubella virus M Dittmar, K Whig, J Miller, B Kamalia, S Suppiah, L Perelygina, ... PNAS nexus 2 (9), pgad256, 2023 | 4 | 2023 |