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Joaquín Arribas
Joaquín Arribas
ICREA Research Professor; Director, Hospital del Mar Research Institute; VHIO
在 researchmar.net 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
Trastuzumab (herceptin), a humanized anti-Her2 receptor monoclonal antibody, inhibits basal and activated Her2 ectodomain cleavage in breast cancer cells
MA Molina, J Codony-Servat, J Albanell, F Rojo, J Arribas, J Baselga
Cancer research 61 (12), 4744-4749, 2001
10722001
Expression of p95HER2, a truncated form of the HER2 receptor, and response to anti-HER2 therapies in breast cancer
M Scaltriti, F Rojo, A Ocaña, J Anido, M Guzman, J Cortes, S Di Cosimo, ...
Journal of the National Cancer Institute 99 (8), 628-638, 2007
10452007
NVP-BEZ235, a dual PI3K/mTOR inhibitor, prevents PI3K signaling and inhibits the growth of cancer cells with activating PI3K mutations
V Serra, B Markman, M Scaltriti, PJA Eichhorn, V Valero, M Guzman, ...
Cancer research 68 (19), 8022-8030, 2008
9252008
Interrogating open issues in cancer precision medicine with patient-derived xenografts
AT Byrne, DG Alférez, F Amant, D Annibali, J Arribas, AV Biankin, A Bruna, ...
Nature Reviews Cancer 17 (4), 254-268, 2017
6602017
PI3K inhibition results in enhanced HER signaling and acquired ERK dependency in HER2-overexpressing breast cancer
V Serra, M Scaltriti, L Prudkin, PJA Eichhorn, YH Ibrahim, ...
Oncogene 30 (22), 2547-2557, 2011
6082011
Diverse Cell Surface Protein Ectodomains Are Shed by a System Sensitive to Metalloprotease Inhibitors (∗)
J Arribas, L Coodly, P Vollmer, TK Kishimoto, S Rose-John, J Massagué
Journal of Biological Chemistry 271 (19), 11376-11382, 1996
5301996
Lapatinib, a HER2 tyrosine kinase inhibitor, induces stabilization and accumulation of HER2 and potentiates trastuzumab-dependent cell cytotoxicity
M Scaltriti, C Verma, M Guzman, J Jimenez, JL Parra, K Pedersen, ...
Oncogene 28 (6), 803-814, 2009
4952009
Metalloprotease-disintegrin MDC9: intracellular maturation and catalytic activity
M Roghani, JD Becherer, ML Moss, RE Atherton, H Erdjument-Bromage, ...
Journal of Biological Chemistry 274 (6), 3531-3540, 1999
4171999
Combined epidermal growth factor receptor targeting with the tyrosine kinase inhibitor gefitinib (ZD1839) and the monoclonal antibody cetuximab (IMC-C225) superiority over …
P Matar, F Rojo, R Cassia, G Moreno-Bueno, S Di Cosimo, J Tabernero, ...
Clinical cancer research 10 (19), 6487-6501, 2004
3682004
TACE is required for the activation of the EGFR by TGF‐α in tumors
M Borrell‐Pagès, F Rojo, J Albanell, J Baselga, J Arribas
The EMBO journal, 2003
3602003
Mechanism of action of trastuzumab and scientific update
J Baselga, J Albanell, MA Molina, J Arribas
Seminars in oncology 28, 4-11, 2001
3602001
RAD51 foci as a functional biomarker of homologous recombination repair and PARP inhibitor resistance in germline BRCA-mutated breast cancer
C Cruz, M Castroviejo-Bermejo, S Gutiérrez-Enríquez, A Llop-Guevara, ...
Annals of Oncology 29 (5), 1203-1210, 2018
3462018
Cleavage of the HER2 ectodomain is a pervanadate-activable process that is inhibited by the tissue inhibitor of metalloproteases-1 in breast cancer cells
J Codony-Servat, J Albanell, JC Lopez-Talavera, J Arribas, J Baselga
Cancer research 59 (6), 1196-1201, 1999
3401999
ZD1839, a specific epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, induces the formation of inactive EGFR/HER2 and EGFR/HER3 heterodimers and prevents …
J Anido, P Matar, J Albanell, M Guzmán, F Rojo, J Arribas, S Averbuch, ...
Clinical Cancer Research 9 (4), 1274-1283, 2003
2992003
Protein ectodomain shedding
J Arribas, A Borroto
Chemical reviews 102 (12), 4627-4638, 2002
2982002
Human MT6-matrix metalloproteinase: identification, progelatinase A activation, and expression in brain tumors
G Velasco, S Cal, A Merlos-Suárez, AA Ferrando, S Alvarez, A Nakano, ...
Cancer Research 60 (4), 877-882, 2000
2902000
Identification and characterization of Cardiac Glycosides as senolytic compounds
F Triana-Martínez, P Picallos-Rabina, S Da Silva-Álvarez, F Pietrocola, ...
Nature communications 10 (1), 4731, 2019
2812019
p95HER2 and breast cancer
J Arribas, J Baselga, K Pedersen, JL Parra-Palau
Cancer research 71 (5), 1515-1519, 2011
2762011
Biosynthesis of tumorigenic HER2 C‐terminal fragments by alternative initiation of translation
J Anido, M Scaltriti, JJ Bech Serra, BS Josefat, F Rojo Todo, J Baselga, ...
The EMBO journal 25 (13), 3234-3244, 2006
2752006
A naturally occurring HER2 carboxy-terminal fragment promotes mammary tumor growth and metastasis
K Pedersen, PD Angelini, S Laos, A Bach-Faig, MP Cunningham, ...
Molecular and cellular biology 29 (12), 3319-3331, 2009
2192009
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