Human β cell transcriptome analysis uncovers lncRNAs that are tissue-specific, dynamically regulated, and abnormally expressed in type 2 diabetes I Morán, I Akerman, M Van De Bunt, R Xie, M Benazra, T Nammo, L Arnes, ... Cell metabolism 16 (4), 435-448, 2012 | 491 | 2012 |
Epigenetic priming of enhancers predicts developmental competence of hESC-derived endodermal lineage intermediates A Wang, F Yue, Y Li, R Xie, T Harper, NA Patel, K Muth, J Palmer, Y Qiu, ... Cell stem cell 16 (4), 386-399, 2015 | 266 | 2015 |
Dynamic chromatin remodeling mediated by polycomb proteins orchestrates pancreatic differentiation of human embryonic stem cells R Xie, LJ Everett, HW Lim, NA Patel, J Schug, E Kroon, OG Kelly, A Wang, ... Cell stem cell 12 (2), 224-237, 2013 | 260 | 2013 |
Single amino acid mutations in the cadherin receptor from Heliothis virescens affect its toxin binding ability to Cry1A toxins R Xie, M Zhuang, LS Ross, I Gomez, DI Oltean, A Bravo, M Soberon, ... Journal of Biological Chemistry 280 (9), 8416-8425, 2005 | 168 | 2005 |
A Sox9/Fgf feed-forward loop maintains pancreatic organ identity PA Seymour, HP Shih, NA Patel, KK Freude, R Xie, CJ Lim, M Sander Development 139 (18), 3363-3372, 2012 | 131 | 2012 |
Urocortin 3 marks mature human primary and embryonic stem cell-derived pancreatic alpha and beta cells T van der Meulen, R Xie, OG Kelly, WW Vale, M Sander, MO Huising PloS one 7 (12), e52181, 2012 | 108 | 2012 |
A gene regulatory network cooperatively controlled by Pdx1 and Sox9 governs lineage allocation of foregut progenitor cells HP Shih, PA Seymour, NA Patel, R Xie, A Wang, PP Liu, GW Yeo, ... Cell reports 13 (2), 326-336, 2015 | 100 | 2015 |
Modulating the phenotype of host macrophages to enhance osteogenesis in MSC-laden hydrogels: design of a glucomannan coating material Y Niu, Q Li, R Xie, S Liu, R Wang, P Xing, Y Shi, Y Wang, L Dong, C Wang Biomaterials 139, 39-55, 2017 | 67 | 2017 |
Decoding the dynamic DNA methylation and hydroxymethylation landscapes in endodermal lineage intermediates during pancreatic differentiation of hESC J Li, X Wu, Y Zhou, M Lee, L Guo, W Han, W Mo, W Cao, D Sun, R Xie, ... Nucleic acids research 46 (6), 2883-2900, 2018 | 66 | 2018 |
Acetylation of AGO2 promotes cancer progression by increasing oncogenic miR-19b biogenesis H Zhang, Y Wang, J Dou, Y Guo, J He, L Li, X Liu, R Chen, R Deng, ... Oncogene 38 (9), 1410-1431, 2019 | 63 | 2019 |
Ros-induced histone modifications and their role in cell survival and cell death TJ Monks, R Xie, K Tikoo, SS Lau Drug metabolism reviews 38 (4), 755-767, 2006 | 60 | 2006 |
PARP-1 hyperactivation and reciprocal elevations in intracellular Ca2+ during ROS-induced nonapoptotic cell death F Zhang, R Xie, FM Munoz, SS Lau, TJ Monks Toxicological Sciences 140 (1), 118-134, 2014 | 56 | 2014 |
Highly Toxic and Broad-Spectrum Insecticidal Bacillus thuringiensis Engineered by Using the Transposon Tn917 and Protoplast Fusion J Yu, Y Pang, M Tang, R Xie, L Tan, S Zeng, M Yuan, J Liu Current Microbiology 43, 112-119, 2001 | 44 | 2001 |
Decoding the role of TET family dioxygenases in lineage specification X Wu, G Li, R Xie Epigenetics & Chromatin 11 (1), 58, 2018 | 40 | 2018 |
Phosphorylation of TET2 by AMPK is indispensable in myogenic differentiation T Zhang, X Guan, UL Choi, Q Dong, MMT Lam, J Zeng, J Xiong, X Wang, ... Epigenetics & Chromatin 12, 1-17, 2019 | 34 | 2019 |
A systems view of epigenetic networks regulating pancreas development and β‐cell function R Xie, AC Carrano, M Sander Wiley Interdisciplinary Reviews: Systems Biology and Medicine 7 (1), 1-11, 2015 | 26 | 2015 |
Anti-tumor effects of a ‘human & mouse cross-reactive’anti-ADAM17 antibody in a pancreatic cancer model in vivo J Ye, SM Yuen, G Murphy, R Xie, HF Kwok European Journal of Pharmaceutical Sciences 110, 62-69, 2017 | 25 | 2017 |
LncRNA UCA1 maintains the low‐tumorigenic and nonmetastatic status by stabilizing E‐cadherin in primary prostate cancer cells X Zhao, Y Wang, J He, R Deng, X Huang, Y Guo, L Li, R Xie, J Yu Molecular Carcinogenesis 59 (10), 1174-1187, 2020 | 17 | 2020 |
TET1 dioxygenase is required for FOXA2-associated chromatin remodeling in pancreatic beta-cell differentiation J Li, X Wu, J Ke, M Lee, Q Lan, J Li, J Yu, Y Huang, DQ Sun, R Xie Nature Communications 13 (1), 3907, 2022 | 13 | 2022 |
PRDM3 attenuates pancreatitis and pancreatic tumorigenesis by regulating inflammatory response J Ye, A Huang, H Wang, AMY Zhang, X Huang, Q Lan, T Sato, S Goyama, ... Cell Death & Disease 11 (3), 187, 2020 | 13 | 2020 |