ATF4 activation promotes hepatic mitochondrial dysfunction by repressing NRF1–TFAM signalling in alcoholic steatohepatitis L Hao, W Zhong, H Dong, W Guo, X Sun, W Zhang, R Yue, T Li, A Griffiths, ... Gut 70 (10), 1933-1945, 2021 | 97 | 2021 |
ER stress-induced upregulation of NNMT contributes to alcohol-related fatty liver development Q Song, Y Chen, J Wang, L Hao, C Huang, A Griffiths, Z Sun, Z Zhou, ... Journal of hepatology 73 (4), 783-793, 2020 | 89 | 2020 |
Elevated circulating stearic acid leads to a major lipotoxic effect on mouse pancreatic beta cells in hyperlipidaemia via a miR-34a-5p-mediated PERK/p53-dependent pathway H Lu, L Hao, S Li, S Lin, L Lv, Y Chen, H Cui, T Zi, X Chu, L Na, C Sun Diabetologia 59 (6), 1247-1257, 2016 | 78 | 2016 |
Mitochondria-targeted ubiquinone (MitoQ) enhances acetaldehyde clearance by reversing alcohol-induced posttranslational modification of aldehyde dehydrogenase 2: a molecular … L Hao, Q Sun, W Zhong, W Zhang, X Sun, Z Zhou Redox biology 14, 626-636, 2018 | 73 | 2018 |
Increase of circulating cholesterol in vitamin D deficiency is linked to reduced vitamin D receptor activity via the Insig‐2/SREBP‐2 pathway S Li, Y He, S Lin, L Hao, Y Ye, L Lv, Z Sun, H Fan, Z Shi, J Li, R Feng, ... Molecular nutrition & food research 60 (4), 798-809, 2016 | 69 | 2016 |
Paneth cell dysfunction mediates alcohol‐related steatohepatitis through promoting bacterial translocation in mice: role of zinc deficiency W Zhong, X Wei, L Hao, TD Lin, R Yue, X Sun, W Guo, H Dong, T Li, ... Hepatology 71 (5), 1575-1591, 2020 | 59 | 2020 |
Fatty acids inhibit LAMP2-mediated autophagy flux via activating ER stress pathway in alcohol-related liver disease W Guo, W Zhong, L Hao, H Dong, X Sun, R Yue, T Li, Z Zhou Cellular and molecular gastroenterology and hepatology 12 (5), 1599-1615, 2021 | 41 | 2021 |
Calcium supplementation increases circulating cholesterol by reducing its catabolism via GPER and TRPC1-dependent pathway in estrogen deficient women S Li, Y Li, H Ning, L Na, Y Niu, M Wang, R Feng, L Liu, F Guo, S Hou, ... International journal of cardiology 168 (3), 2548-2560, 2013 | 33 | 2013 |
Activation of PPARα-catalase pathway reverses alcoholic liver injury via upregulating NAD synthesis and accelerating alcohol clearance R Yue, G Chen, G Xie, L Hao, W Guo, X Sun, W Jia, Q Zhang, Z Zhou, ... Free radical biology and medicine 174, 249-263, 2021 | 30 | 2021 |
Activation of AhR-NQO1 signaling pathway protects against alcohol-induced liver injury by improving redox balance H Dong, L Hao, W Zhang, W Zhong, W Guo, R Yue, X Sun, Z Zhou Cellular and molecular gastroenterology and hepatology 12 (3), 793-811, 2021 | 25 | 2021 |
Insulin protects hepatic lipotoxicity by regulating ER stress through the PI3K/Akt/p53 involved pathway independently of autophagy inhibition H Ning, Z Sun, Y Liu, L Liu, L Hao, Y Ye, R Feng, J Li, Y Li, X Chu, S Li, ... Nutrients 8 (4), 227, 2016 | 22 | 2016 |
Activation of mTORC1 by free fatty acids suppresses LAMP2 and autophagy function via ER stress in alcohol-related liver disease W Guo, W Zhong, L Hao, X Sun, Z Zhou Cells 10 (10), 2730, 2021 | 17 | 2021 |
Loss of long-chain acyl-CoA synthetase 1 promotes hepatocyte death in alcohol-induced steatohepatitis H Dong, W Zhong, W Zhang, L Hao, W Guo, R Yue, X Sun, Z Sun, ... Metabolism 138, 155334, 2023 | 16 | 2023 |
Conventional type 1 dendritic cells protect against gut barrier disruption via maintaining Akkermansia muciniphila in alcoholic steatohepatitis L Hao, W Zhong, J Woo, X Wei, H Ma, H Dong, W Guo, X Sun, R Yue, ... Hepatology 78 (3), 896-910, 2023 | 11 | 2023 |
TLR9 signaling protects alcohol-induced hepatic oxidative stress but worsens liver inflammation in mice L Hao, W Zhong, X Sun, Z Zhou Frontiers in Pharmacology 12, 709002, 2021 | 8 | 2021 |
Promoting intestinal antimicrobial defense and microbiome symbiosis contributes to IL-22-mediated protection against alcoholic hepatitis in mice R Yue, X Wei, L Hao, H Dong, W Guo, X Sun, J Zhao, Z Zhou, W Zhong Frontiers in Immunology 14, 1289356, 2023 | 3 | 2023 |
Small intestinal lamina propria immune cells dyshomeostasis is associated with alcoholic steatohepatitis in the mouse L Hao, W Zhong, X Sun, Z Zhou The Journal of Immunology 202 (1_Supplement), 182.33-182.33, 2019 | 1 | 2019 |
Reversal of hepatic accumulation of nordeoxycholic acid underlines the beneficial effects of cholestyramine on alcohol-associated liver disease in mice W Guo, W Zhong, L He, X Wei, L Hao, H Dong, R Yue, X Sun, X Yin, ... Hepatology Communications 8 (8), e0507, 2024 | | 2024 |
Conventional type 1 dendritic cells protect against gut barrier disruption via maintaining A. muciniphila in alcoholic 2 steatohepatitis 3 L Hao, W Zhong, J Woo, X Wei, H Ma, Z Zhou | | 2023 |
INHIBITION OF HEPATIC TRIGLYCERIDE SYNTHESIS EXAGGERATES ALCOHOL-INDUCED HEPATIC LIPOTOXICITY IN MICE BY ACTIVATING mTORC1-ER STRESS PATHWAY AND SUPPRESSING LAMP2-MEIDATED … W Guo, W Zhong, L Hao, H Dong, X Sun, R Yue, Z Zhou HEPATOLOGY 76, S988-S988, 2022 | | 2022 |