Cancer cells tune the signaling pathways to empower de novo synthesis of nucleotides E Villa, ES Ali, U Sahu, I Ben-Sahra Cancers 11 (5), 688, 2019 | 226 | 2019 |
mTORC1 stimulates cell growth through SAM synthesis and m6A mRNA-dependent control of protein synthesis E Villa, U Sahu, BP O’Hara, ES Ali, KA Helmin, JM Asara, P Gao, ... Molecular cell 81 (10), 2076-2093. e9, 2021 | 105 | 2021 |
ERK2 phosphorylates PFAS to mediate posttranslational control of de novo purine synthesis ES Ali, U Sahu, E Villa, BP O’Hara, P Gao, C Beaudet, AW Wood, ... Molecular cell 78 (6), 1178-1191. e6, 2020 | 52 | 2020 |
Trm1p, a Zn (II) 2Cys6-type transcription factor, is essential for the transcriptional activation of genes of methanol utilization pathway, in Pichia pastoris U Sahu, KK Rao, PN Rangarajan Biochemical and Biophysical Research Communications 451 (1), 158-164, 2014 | 51 | 2014 |
Purine nucleotide depletion prompts cell migration by stimulating the serine synthesis pathway MH Soflaee, R Kesavan, U Sahu, A Tasdogan, E Villa, Z Djabari, F Cai, ... Nature communications 13 (1), 2698, 2022 | 37 | 2022 |
Regulation of acetate metabolism and acetyl Co-A synthetase 1 (ACS1) expression by methanol expression regulator 1 (Mxr1p) in the methylotrophic yeast Pichia pastoris U Sahu, PN Rangarajan Journal of Biological Chemistry 291 (7), 3648-3657, 2016 | 22 | 2016 |
Methanol expression regulator 1 (Mxr1p) is essential for the utilization of amino acids as the sole source of carbon by the methylotrophic yeast, Pichia pastoris U Sahu, PN Rangarajan Journal of Biological Chemistry 291 (39), 20588-20601, 2016 | 21 | 2016 |
NOTCH1-driven UBR7 stimulates nucleotide biosynthesis to promote T cell acute lymphoblastic leukemia S Srivastava, U Sahu, Y Zhou, AK Hogan, KM Sathyan, J Bodner, ... Science Advances 7 (5), eabc9781, 2021 | 15 | 2021 |
Methionine synthase is localized to the nucleus in Pichia pastoris and Candida albicans and to the cytoplasm in Saccharomyces cerevisiae U Sahu, VKH Rajendra, SS Kapnoor, R Bhagavat, N Chandra, ... Journal of Biological Chemistry 292 (36), 14730-14746, 2017 | 12 | 2017 |
Characterization of the transactivation and nuclear localization functions of Pichia pastoris zinc finger transcription factor Mxr1p A Gupta, KK Rao, U Sahu, PN Rangarajan Journal of Biological Chemistry 297 (4), 2021 | 7 | 2021 |
GATOR2 rings GATOR1 to speak to mTORC1 U Sahu, I Ben-Sahra Molecular Cell 83 (1), 6-8, 2023 | 5 | 2023 |
Pyrimidines maintain mitochondrial pyruvate oxidation to support de novo lipogenesis. U Sahu, E Villa, CR Reczek, Z Zhao, BP O’Hara, MD Torno, R Mishra, ... Science 383 (6690), 1484-1492, 2024 | 4 | 2024 |
Function and regulation of an aldehyde dehydrogenase essential for ethanol and methanol metabolism of the yeast, Komagataella phaffii KK Rao, U Sahu, PN Rangarajan bioRxiv, 2020.06. 14.151365, 2020 | 1 | 2020 |
Exploiting De Novo Serine Synthesis as a Metabolic Vulnerability to Overcome Sunitinib Resistance in Advanced Renal Cell Carcinoma M Teisseire, U Sahu, J Parola, MC Tsai, V Vial, J Durivault, R Grepin, ... bioRxiv, 2024.03. 22.586287, 2024 | | 2024 |
The cell cycle loops UTP around CAD U Sahu, I Ben-Sahra Nature Metabolism 5 (2), 199-200, 2023 | | 2023 |
Mxr1p is a Global Regulator of Multiple Metabolic Pathways in the Methylotrophic Yeast Pichia Pastoris U Sahu | | 2018 |