The role of metallobiology and amyloid‐β peptides in Alzheimer’s disease BR Roberts, TM Ryan, AI Bush, CL Masters, JA Duce Journal of Neurochemistry 120, 149, 2012 | 333 | 2012 |
Utility of an improved model of amyloid-beta (Abeta1-42) toxicity in Caenorhabditis elegans for drug screening for Alzheimer's disease G McColl, BR Roberts, TL Pukala, VB Kenche, CM Roberts, CD Link, ... Molecular Neurodegeneration 7 (1), 57, 2012 | 259 | 2012 |
2017 publication guidelines for structural modelling of small-angle scattering data from biomolecules in solution: an update J Trewhella, AP Duff, D Durand, F Gabel, JM Guss, WA Hendrickson, ... Acta Crystallographica Section D: Structural Biology 73 (9), 710-728, 2017 | 221 | 2017 |
Improved radiation dose efficiency in solution SAXS using a sheath flow sample environment N Kirby, N Cowieson, AM Hawley, ST Mudie, DJ McGillivray, M Kusel, ... Acta Crystallographica Section D: Structural Biology 72 (12), 1254-1266, 2016 | 152 | 2016 |
Biochemically-defined pools of amyloid-β in sporadic Alzheimer’s disease: correlation with amyloid PET BR Roberts, M Lind, AZ Wagen, A Rembach, T Frugier, QX Li, TM Ryan, ... Brain 140 (5), 1486-1498, 2017 | 144 | 2017 |
Ammonium hydroxide treatment of Aβ produces an aggregate free solution suitable for biophysical and cell culture characterization TM Ryan, J Caine, HDT Mertens, N Kirby, J Nigro, K Breheney, ... PeerJ 1, e73, 2013 | 124 | 2013 |
Stabilization of nontoxic Aβ-oligomers: insights into the mechanism of action of hydroxyquinolines in Alzheimer's disease TM Ryan, BR Roberts, G McColl, DJ Hare, PA Doble, QX Li, M Lind, ... Journal of Neuroscience 35 (7), 2871-2884, 2015 | 88 | 2015 |
Nanostructure of electrospun collagen: do electrospun collagen fibers form native structures? KH Sizeland, KA Hofman, IC Hallett, DE Martin, J Potgieter, NM Kirby, ... Materialia 3, 90-96, 2018 | 85 | 2018 |
Metalloproteomics: Principles, challenges and applications to neurodegeneration BR Roberts, A Lothian, DJ Hare, CL Masters, TM Ryan, R Grimm Frontiers in Aging Neuroscience 1, 0, 2013 | 81* | 2013 |
PcoE–a metal sponge expressed to the periplasm of copper resistance E. coli. Implication of its function role in copper resistance M Zimmermann, S Udagedara, CM Sze, TM Ryan, GJ Howlett, Z Xiao, ... Journal of Inorganic Biochemistry 115, 186-197, 2012 | 81 | 2012 |
An optimized SEC-SAXS system enabling high X-ray dose for rapid SAXS assessment with correlated UV measurements for biomolecular structure analysis TM Ryan, J Trewhella, JM Murphy, JR Keown, L Casey, FG Pearce, ... Journal of applied crystallography 51 (1), 97-111, 2018 | 78 | 2018 |
The effect of paraformaldehyde fixation and sucrose cryoprotection on metal concentration in murine neurological tissue DJ Hare, JL George, L Bray, I Volitakis, A Vais, TM Ryan, RA Cherny, ... Journal of Analytical Atomic Spectrometry 29 (3), 565-570, 2014 | 59 | 2014 |
Profiling the iron, copper and zinc content in primary neuron and astrocyte cultures by rapid online quantitative size exclusion chromatography-inductively coupled plasma-mass … DJ Hare, A Grubman, TM Ryan, A Lothian, JR Liddell, R Grimm, ... Metallomics 5 (12), 1656-1662, 2013 | 58 | 2013 |
Small amphipathic molecules modulate the secondary structure and amyloid fibril forming kinetics of the Alzheimer's disease peptide Aβ1-42 TM Ryan, A Friedhuber, M Lind, GJ Howlett, CL Masters, BR Roberts Journal of Biological Chemistry, 2012 | 53 | 2012 |
Domain organization of the monomeric form of the Tom70 mitochondrial import receptor RD Mills, J Trewhella, TW Qiu, T Welte, TM Ryan, T Hanley, RB Knott, ... Journal of molecular biology 388 (5), 1043-1058, 2009 | 46 | 2009 |
Effects of polysaccharide charge pattern on the microstructures of β-lactoglobulin-pectin complex coacervates, studied by SAXS and SANS AY Xu, LD Melton, TM Ryan, JP Mata, A Rekas, MAK Williams, ... Food Hydrocolloids 77, 952-963, 2018 | 44 | 2018 |
Fluorescence detection of a lipid-induced tetrameric intermediate in amyloid fibril formation by apolipoprotein C-II TM Ryan, GJ Howlett, MF Bailey Journal of Biological Chemistry 283 (50), 35118-35128, 2008 | 42 | 2008 |
High-affinity amphipathic modulators of amyloid fibril nucleation and elongation TM Ryan, MDW Griffin, CL Teoh, J Ooi, GJ Howlett Journal of molecular biology 406 (3), 416-429, 2011 | 36 | 2011 |
The acute phase protein lactoferrin is a key feature of Alzheimer’s disease and predictor of Aβ burden through induction of APP amyloidogenic processing A Tsatsanis, AN McCorkindale, BX Wong, E Patrick, TM Ryan, RW Evans, ... Molecular psychiatry 26 (10), 5516-5531, 2021 | 33 | 2021 |
Sedimentation velocity analysis of amyloid oligomers and fibrils using fluorescence detection YF Mok, TM Ryan, S Yang, DM Hatters, GJ Howlett, MDW Griffin Methods 54 (1), 67-75, 2011 | 33 | 2011 |