| High-resolution CRISPR screens reveal fitness genes and genotype-specific cancer liabilities T Hart, M Chandrashekhar, M Aregger, Z Steinhart, KR Brown, ... Cell 163 (6), 1515-1526, 2015 | 1671 | 2015 |
| Evaluation and design of genome-wide CRISPR/SpCas9 knockout screens T Hart, AHY Tong, K Chan, J Van Leeuwen, A Seetharaman, M Aregger, ... G3: Genes, Genomes, Genetics 7 (8), 2719-2727, 2017 | 522 | 2017 |
| Essential gene profiles in breast, pancreatic, and ovarian cancer cells R Marcotte, KR Brown, F Suarez, A Sayad, K Karamboulas, ... Cancer discovery 2 (2), 172-189, 2012 | 383 | 2012 |
| Functional genomic landscape of cancer-intrinsic evasion of killing by T cells KA Lawson, CM Sousa, X Zhang, E Kim, R Akthar, JJ Caumanns, Y Yao, ... Nature 586 (7827), 120-126, 2020 | 316 | 2020 |
| A negative genetic interaction map in isogenic cancer cell lines reveals cancer cell vulnerabilities FJ Vizeacoumar, R Arnold, FS Vizeacoumar, M Chandrashekhar, ... Molecular systems biology 9 (1), 696, 2013 | 112 | 2013 |
| Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism M Aregger, KA Lawson, M Billmann, M Costanzo, AHY Tong, K Chan, ... Nature metabolism 2 (6), 499-513, 2020 | 87 | 2020 |
| Dynamics of macrophage trogocytosis of rituximab-coated B cells T Pham, P Mero, JW Booth PLoS One 6 (1), e14498, 2011 | 69 | 2011 |
| Essential gene profiles in breast, pancreatic, and ovarian cancer cells. Cancer Discov. 2012; 2: 172–189. doi: 10.1158/2159-8290 R Marcotte, KR Brown, F Suarez, A Sayad, K Karamboulas, ... CD-11-0224.[Europe PMC free article][Abstract][CrossRef][Google Scholar], 2012 | 59 | 2012 |
| Cancer-selective metabolic vulnerabilities in MYC-amplified medulloblastoma WD Gwynne, Y Suk, S Custers, N Mikolajewicz, JK Chan, Z Zador, ... Cancer Cell 40 (12), 1488-1502. e7, 2022 | 39 | 2022 |
| Differential recruitment of activating and inhibitory FcγRII during phagocytosis S Syam, P Mero, T Pham, CA McIntosh, P Bruhns, JW Booth The Journal of Immunology 184 (6), 2966-2973, 2010 | 36 | 2010 |
| Prolonging microtubule dysruption enhances the immunogenicity of chronic lymphocytic leukaemia cells SP Shaha, J Tomic, Y Shi, T Pham, P Mero, D White, L He, JL Baryza, ... Clinical & Experimental Immunology 158 (2), 186-198, 2009 | 34 | 2009 |
| Phosphorylation-independent ubiquitylation and endocytosis of FcγRIIA P Mero, CY Zhang, ZY Huang, MK Kim, AD Schreiber, S Grinstein, ... Journal of Biological Chemistry 281 (44), 33242-33249, 2006 | 34 | 2006 |
| Dependence of human colorectal cells lacking the FBW7 tumor suppressor on the spindle assembly checkpoint ML Bailey, T Singh, P Mero, J Moffat, P Hieter Genetics 201 (3), 885-895, 2015 | 26 | 2015 |
| Pooled CRISPR-based genetic screens in mammalian cells K Chan, AHY Tong, KR Brown, P Mero, J Moffat JoVE (Journal of Visualized Experiments), e59780, 2019 | 18 | 2019 |
| Survival-based CRISPR genetic screens across a panel of permissive cell lines identify common and cell-specific SARS-CoV-2 host factors K Chan, AG Farias, H Lee, F Guvenc, P Mero, KR Brown, H Ward, ... Heliyon 9 (1), 2023 | 14 | 2023 |
| Forward genetic screen in human podocytes identifies diphthamide biosynthesis genes as regulators of adhesion DP Cinà, T Ketela, KR Brown, M Chandrashekhar, P Mero, C Li, T Onay, ... American Journal of Physiology-Renal Physiology 317 (6), F1593-F1604, 2019 | 8 | 2019 |
| Chemical genomics with pyrvinium identifies C1orf115 as a regulator of drug efflux SN Masud, M Chandrashekhar, M Aregger, G Tan, X Zhang, P Mero, ... Nature Chemical Biology 18 (12), 1370-1379, 2022 | 4 | 2022 |
| The TSC22D, WNK, and NRBP gene families exhibit functional buffering and evolved with Metazoa for cell volume regulation YX Xiao, SY Lee, M Aguilera-Uribe, R Samson, A Au, Y Khanna, Z Liu, ... Cell reports 43 (7), 2024 | 2 | 2024 |
| Systematic genome-scale identification of host factors for SARS-CoV-2 infection across models yields a core single gene dependency; ACE2 K Chan, AG Farias, H Lee, F Guvenc, P Mero, K Aulakh, KR Brown, ... BioRxiv, 2021.06. 28.450244, 2021 | 2 | 2021 |
| Cell cycle regulation of mitochondrial protein import revealed by genome-scale pooled bimolecular fluorescence complementation screening K Blakely, P Mero, R Arnold, A Saleem, C Misquitta, D Kasimer, S Kumar, ... bioRxiv, 770669, 2019 | 1 | 2019 |
