Phase separation of p53 precedes aggregation and is affected by oncogenic mutations and ligands EC Petronilho, MM Pedrote, MA Marques, YM Passos, MF Mota, ... Chemical science 12 (21), 7334-7349, 2021 | 56 | 2021 |
CryoEM maps are full of potential MA Marques, MD Purdy, M Yeager Current Opinion in Structural Biology 58, 214-223, 2019 | 50 | 2019 |
The status of p53 oligomeric and aggregation states in cancer GAP de Oliveira, EC Petronilho, MM Pedrote, MA Marques, TCRG Vieira, ... Biomolecules 10 (4), 548, 2020 | 48 | 2020 |
Structural basis for the dissociation of α-synuclein fibrils triggered by pressure perturbation of the hydrophobic core GAP de Oliveira, MA Marques, C Cruzeiro-Silva, Y Cordeiro, C Schuabb, ... Scientific reports 6 (1), 37990, 2016 | 43 | 2016 |
Aggregation-primed molten globule conformers of the p53 core domain provide potential tools for studying p53C aggregation in cancer MM Pedrote, GAP de Oliveira, AL Felix, MF Mota, MA Marques, IN Soares, ... Journal of Biological Chemistry 293 (29), 11374-11387, 2018 | 37 | 2018 |
Cardiac troponin and tropomyosin: structural and cellular perspectives to unveil the hypertrophic cardiomyopathy phenotype MA Marques, GAP De Oliveira Frontiers in physiology 7, 429, 2016 | 37 | 2016 |
The intrinsically disordered C terminus of troponin T binds to troponin C to modulate myocardial force generation JR Johnston, M Landim-Vieira, MA Marques, GAP De Oliveira, ... Journal of Biological Chemistry 294 (52), 20054-20069, 2019 | 26 | 2019 |
Amide hydrogens reveal a temperature-dependent structural transition that enhances site-II Ca2+-binding affinity in a C-domain mutant of cardiac troponin C T Veltri, GAP de Oliveira, EA Bienkiewicz, FL Palhano, MA Marques, ... Scientific reports 7 (1), 691, 2017 | 26 | 2017 |
Targeting biomolecular condensation and protein aggregation against cancer JL Silva, D Foguel, VF Ferreira, TCRG Vieira, MA Marques, GDS Ferretti, ... Chemical reviews 123 (14), 9094-9138, 2023 | 20 | 2023 |
Allosteric transmission along a loosely structured backbone allows a cardiac troponin C mutant to function with only one Ca2+ ion MA Marques, JR Pinto, AH Moraes, A Iqbal, MTQ de Magalhães, ... Biophysical Journal 112 (3), 62a, 2017 | 17 | 2017 |
New heteroleptic ruthenium (II) complexes with sulfamethoxypyridazine and diimines as potential antitumor agents ACC de Melo, JM Santana, KJRC Nunes, BL Rodrigues, N Castilho, ... Molecules 24 (11), 2154, 2019 | 13 | 2019 |
Insights into the intramolecular coupling between the N-and C-domains of troponin C derived from high-pressure, fluorescence, nuclear magnetic resonance, and small-angle X-ray … GAP de Oliveira, CB Rocha, MA Marques, Y Cordeiro, MM Sorenson, ... Biochemistry 52 (1), 28-40, 2013 | 13 | 2013 |
Protein of a thousand faces: The tumor-suppressive and oncogenic responses of p53 MA Marques, GC Andrade, JL Silva, GAP de Oliveira Frontiers in molecular biosciences 9, 944955, 2022 | 11 | 2022 |
The missing links within troponin MA Marques, MS Parvatiyar, W Yang, GAP de Oliveira, JR Pinto Archives of biochemistry and biophysics 663, 95-100, 2019 | 9 | 2019 |
O movimento de Titularização de Activos em Portugal J Pinto, M Marques Cadernos do Mercado de Valores Mobiliários 26, 8-45, 2007 | 9 | 2007 |
Anomalous structural dynamics of minimally frustrated residues in cardiac troponin C triggers hypertrophic cardiomyopathy MA Marques, M Landim-Vieira, AH Moraes, B Sun, JR Johnston, ... Chemical science 12 (21), 7308-7323, 2021 | 7 | 2021 |
Conformational stability of SARS-CoV-2 glycoprotein spike variants HRS Arruda, TM Lima, RGF Alvim, FBA Victorio, DPB Abreu, FF Marsili, ... Iscience 26 (1), 2023 | 6 | 2023 |
The chameleonic behavior of p53 in health and disease: the transition from a client to an aberrant condensate scaffold in cancer MA Marques, GAP de Oliveira, JL Silva Essays in Biochemistry 66 (7), 1023-1033, 2022 | 6 | 2022 |
High pressure studies on the misfolding and aggregation of p53 in cancer and of α-synuclein in Parkinson’s disease GAP de Oliveira, MA Marques, MM Pedrote, JL Silva High Pressure Research 39 (2), 193-201, 2019 | 5 | 2019 |
Interactions of ruthenium (II) compounds with sulfasalazine and N, N′-heterocyclic ligands with proteins ACC de Melo, JMSVP Santana, KJR da Costa Nunes, ... Inorganica Chimica Acta 467, 385-390, 2017 | 5 | 2017 |