Sequence-based design of bioactive small molecules that target precursor microRNAs SP Velagapudi, SM Gallo, MD Disney Nature chemical biology 10 (4), 291-297, 2014 | 342 | 2014 |
Effect of COVID-19 pandemic lockdowns on planned cancer surgery for 15 tumour types in 61 countries: an international, prospective, cohort study J Glasbey, A Ademuyiwa, A Adisa, E AlAmeer, AP Arnaud, F Ayasra, ... The Lancet Oncology 22 (11), 1507-1517, 2021 | 247 | 2021 |
Inforna 2.0: a platform for the sequence-based design of small molecules targeting structured RNAs MD Disney, AM Winkelsas, SP Velagapudi, M Southern, M Fallahi, ... ACS chemical biology 11 (6), 1720-1728, 2016 | 204 | 2016 |
Design of a small molecule against an oncogenic noncoding RNA SP Velagapudi, MD Cameron, CL Haga, LH Rosenberg, M Lafitte, ... Proceedings of the National Academy of Sciences 113 (21), 5898-5903, 2016 | 195 | 2016 |
Small molecule inhibition of microRNA-210 reprograms an oncogenic hypoxic circuit MG Costales, CL Haga, SP Velagapudi, JL Childs-Disney, DG Phinney, ... Journal of the American Chemical Society 139 (9), 3446-3455, 2017 | 168 | 2017 |
Small molecule targeted recruitment of a nuclease to RNA MG Costales, Y Matsumoto, SP Velagapudi, MD Disney Journal of the American Chemical Society 140 (22), 6741-6744, 2018 | 166 | 2018 |
Two-dimensional combinatorial screening identifies specific aminoglycoside− RNA internal loop partners MD Disney, LP Labuda, DJ Paul, SG Poplawski, A Pushechnikov, T Tran, ... Journal of the American Chemical Society 130 (33), 11185-11194, 2008 | 155 | 2008 |
Small-molecule targeted recruitment of a nuclease to cleave an oncogenic RNA in a mouse model of metastatic cancer MG Costales, H Aikawa, Y Li, JL Childs-Disney, D Abegg, DG Hoch, ... Proceedings of the National Academy of Sciences 117 (5), 2406-2411, 2020 | 135 | 2020 |
Preoperative nasopharyngeal swab testing and postoperative pulmonary complications in patients undergoing elective surgery during the SARS-CoV-2 pandemic British Journal of Surgery 108 (1), 88-96, 2021 | 95 | 2021 |
Defining RNA–small molecule affinity landscapes enables design of a small molecule inhibitor of an oncogenic noncoding RNA SP Velagapudi, Y Luo, T Tran, HS Haniff, Y Nakai, M Fallahi, GJ Martinez, ... ACS Central Science 3 (3), 205-216, 2017 | 91 | 2017 |
Structure-activity relationships through sequencing (StARTS) defines optimal and suboptimal RNA motif targets for small molecules SP Velagapudi, SJ Seedhouse, MD Disney Angewandte Chemie (International ed. in English) 49 (22), 3816, 2010 | 83 | 2010 |
Translation of the intrinsically disordered protein α-synuclein is inhibited by a small molecule targeting its structured mRNA P Zhang, HJ Park, J Zhang, E Junn, RJ Andrews, SP Velagapudi, ... Proceedings of the National Academy of Sciences 117 (3), 1457-1467, 2020 | 82 | 2020 |
Approved anti-cancer drugs target oncogenic non-coding RNAs SP Velagapudi, MG Costales, BR Vummidi, Y Nakai, AJ Angelbello, ... Cell Chemical Biology 25 (9), 1086-1094. e7, 2018 | 81 | 2018 |
Defining the RNA internal loops preferred by benzimidazole derivatives via 2D combinatorial screening and computational analysis SP Velagapudi, SJ Seedhouse, J French, MD Disney Journal of the American Chemical Society 133 (26), 10111-10118, 2011 | 71 | 2011 |
A designed small molecule inhibitor of a non-coding RNA sensitizes HER2 negative cancers to herceptin MG Costales, DG Hoch, D Abegg, JL Childs-Disney, SP Velagapudi, ... Journal of the American Chemical Society 141 (7), 2960-2974, 2019 | 62 | 2019 |
Two-dimensional combinatorial screening enables the bottom-up design of a microRNA-10b inhibitor SP Velagapudi, MD Disney Chemical Communications 50 (23), 3027-3029, 2014 | 62 | 2014 |
Inhibition of non-ATG translational events in cells via covalent small molecules targeting RNA WY Yang, HD Wilson, SP Velagapudi, MD Disney Journal of the American Chemical Society 137 (16), 5336-5345, 2015 | 61 | 2015 |
Head and neck cancer surgery during the COVID‐19 pandemic: an international, multicenter, observational cohort study COVIDSurg Collaborative, R Shaw, SC Winter, J Glasbey, MWS Ho, ... Cancer 127 (14), 2476-2488, 2021 | 60 | 2021 |
Small molecule inhibition of miR-544 biogenesis disrupts adaptive responses to hypoxia by modulating ATM-mTOR signaling CL Haga, SP Velagapudi, JR Strivelli, WY Yang, MD Disney, DG Phinney ACS chemical biology 10 (10), 2267-2276, 2015 | 60 | 2015 |
Small molecule chemical probes of microRNA function SP Velagapudi, BR Vummidi, MD Disney Current opinion in chemical biology 24, 97-103, 2015 | 53 | 2015 |