Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from L cells and alpha cells H Ellingsgaard, I Hauselmann, B Schuler, AM Habib, LL Baggio, DT Meier, ... Nature medicine 17 (11), 1481-1489, 2011 | 1022 | 2011 |
Tumor necrosis factor-α induces skeletal muscle insulin resistance in healthy human subjects via inhibition of Akt substrate 160 phosphorylation P Plomgaard, K Bouzakri, R Krogh-Madsen, B Mittendorfer, JR Zierath, ... Diabetes 54 (10), 2939-2945, 2005 | 775 | 2005 |
Free fatty acids induce a proinflammatory response in islets via the abundantly expressed interleukin-1 receptor I M Böni-Schnetzler, S Boller, S Debray, K Bouzakri, DT Meier, R Prazak, ... Endocrinology 150 (12), 5218-5229, 2009 | 424 | 2009 |
Reduced activation of phosphatidylinositol-3 kinase and increased serine 636 phosphorylation of insulin receptor substrate-1 in primary culture of skeletal muscle cells from … K Bouzakri, M Roques, P Gual, S Espinosa, F Guebre-Egziabher, JP Riou, ... Diabetes 52 (6), 1319-1325, 2003 | 381 | 2003 |
Signaling specificity of interleukin-6 action on glucose and lipid metabolism in skeletal muscle L Al-Khalili, K Bouzakri, S Glund, F Lönnqvist, HA Koistinen, A Krook Molecular endocrinology 20 (12), 3364-3375, 2006 | 305 | 2006 |
siRNA-based gene silencing reveals specialized roles of IRS-1/Akt2 and IRS-2/Akt1 in glucose and lipid metabolism in human skeletal muscle K Bouzakri, A Zachrisson, L Al-Khalili, BB Zhang, HA Koistinen, A Krook, ... Cell metabolism 4 (1), 89-96, 2006 | 272 | 2006 |
Suppressor of cytokine signaling 3 expression and insulin resistance in skeletal muscle of obese and type 2 diabetic patients J Rieusset, K Bouzakri, E Chevillotte, N Ricard, D Jacquet, JP Bastard, ... Diabetes 53 (9), 2232-2241, 2004 | 254 | 2004 |
Lymphocyte-derived exosomal microRNAs promote pancreatic β cell death and may contribute to type 1 diabetes development C Guay, JK Kruit, S Rome, V Menoud, NL Mulder, A Jurdzinski, ... Cell metabolism 29 (2), 348-361. e6, 2019 | 235 | 2019 |
MAP4K4 gene silencing in human skeletal muscle prevents tumor necrosis factor-α-induced insulin resistance K Bouzakri, JR Zierath Journal of Biological chemistry 282 (11), 7783-7789, 2007 | 212 | 2007 |
Molecular mechanisms of skeletal muscle insulin resistance in type 2 diabetes K Bouzakri, HA Koistinen, JR Zierath Current diabetes reviews 1 (2), 167-174, 2005 | 144 | 2005 |
Bimodal effect on pancreatic β-cells of secretory products from normal or insulin-resistant human skeletal muscle K Bouzakri, P Plomgaard, T Berney, MY Donath, BK Pedersen, ... Diabetes 60 (4), 1111-1121, 2011 | 143 | 2011 |
Identification of a SIRT1 mutation in a family with type 1 diabetes A Biason-Lauber, M Böni-Schnetzler, BP Hubbard, K Bouzakri, A Brunner, ... Cell metabolism 17 (3), 448-455, 2013 | 134 | 2013 |
Circulating follistatin is liver-derived and regulated by the glucagon-to-insulin ratio JS Hansen, S Rutti, C Arous, JO Clemmesen, NH Secher, A Drescher, ... The Journal of Clinical Endocrinology & Metabolism 101 (2), 550-560, 2016 | 129 | 2016 |
IL-4 and IL-13 up-regulate intestinal trefoil factor expression: requirement for STAT6 and de novo protein synthesis C Blanchard, S Durual, M Estienne, K Bouzakri, MH Heim, N Blin, ... The Journal of Immunology 172 (6), 3775-3783, 2004 | 128 | 2004 |
siRNA-mediated reduction of inhibitor of nuclear factor-κB kinase prevents tumor necrosis factor-α–induced insulin resistance in human skeletal muscle RL Austin, A Rune, K Bouzakri, JR Zierath, A Krook Diabetes 57 (8), 2066-2073, 2008 | 124 | 2008 |
Skeletal muscle-released extracellular vesicles: state of the art S Rome, A Forterre, ML Mizgier, K Bouzakri Frontiers in physiology 10, 929, 2019 | 117 | 2019 |
Human skeletal myotubes display a cell-autonomous circadian clock implicated in basal myokine secretion L Perrin, U Loizides-Mangold, S Skarupelova, P Pulimeno, S Chanon, ... Molecular metabolism 4 (11), 834-845, 2015 | 97 | 2015 |
Malonyl CoenzymeA decarboxylase regulates lipid and glucose metabolism in human skeletal muscle K Bouzakri, R Austin, A Rune, ME Lassman, PM Garcia-Roves, JP Berger, ... Diabetes 57 (6), 1508-1516, 2008 | 96 | 2008 |
Pax6 controls the expression of critical genes involved in pancreatic α cell differentiation and function Y Gosmain, E Marthinet, C Cheyssac, A Guérardel, A Mamin, LS Katz, ... Journal of Biological Chemistry 285 (43), 33381-33393, 2010 | 90 | 2010 |
The expression of the p85α subunit of phosphatidylinositol 3-kinase is induced by activation of the peroxisome proliferator-activated receptor γ in human adipocytes J Rieusset, C Chambrier, K Bouzakri, E Dusserre, J Auwerx, JP Riou, ... Diabetologia 44, 544-554, 2001 | 87 | 2001 |