| A method and server for predicting damaging missense mutations IA Adzhubei, S Schmidt, L Peshkin, VE Ramensky, A Gerasimova, P Bork, ... Nature methods 7 (4), 248-249, 2010 | 14247 | 2010 |
| Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project Management Group Liefer Laura A. 51 Wetterstrand Kris A. 51 Good Peter J. 51 ... nature 447 (7146), 799-816, 2007 | 6050 | 2007 |
| Predicting functional effect of human missense mutations using PolyPhen‐2 I Adzhubei, DM Jordan, SR Sunyaev Current protocols in human genetics 76 (1), 7.20. 1-7.20. 41, 2013 | 3761 | 2013 |
| Human mutation rate associated with DNA replication timing JA Stamatoyannopoulos, I Adzhubei, RE Thurman, GV Kryukov, ... Nature genetics 41 (4), 393-395, 2009 | 465 | 2009 |
| A universal trend of amino acid gain and loss in protein evolution IK Jordan, FA Kondrashov, IA Adzhubei, YI Wolf, EV Koonin, ... Nature 433 (7026), 633-638, 2005 | 324 | 2005 |
| No evidence that selection has been less effective at removing deleterious mutations in Europeans than in Africans R Do, D Balick, H Li, I Adzhubei, S Sunyaev, D Reich Nature genetics 47 (2), 126-131, 2015 | 202 | 2015 |
| Mutation mapping and identification by whole-genome sequencing I Leshchiner, K Alexa, P Kelsey, I Adzhubei, CA Austin-Tse, JD Cooney, ... Genome research 22 (8), 1541-1548, 2012 | 153 | 2012 |
| Non-random usage of ‘degenerate’ codons is related to protein three-dimensional structure AA Adzhubei, IA Adzhubei, IA Krasheninnikov, S Neidle FEBS Letters 399 (1-2), 78-82, 1996 | 125 | 1996 |
| An international effort towards developing standards for best practices in analysis, interpretation and reporting of clinical genome sequencing results in the CLARITY Challenge CA Brownstein, AH Beggs, N Homer, B Merriman, TW Yu, KC Flannery, ... Genome biology 15, 1-18, 2014 | 124 | 2014 |
| Calibration of multiple in silico tools for predicting pathogenicity of mismatch repair gene missense substitutions BA Thompson, MS Greenblatt, MP Vallee, JC Herkert, C Tessereau, ... Human mutation 34 (1), 255-265, 2013 | 115 | 2013 |
| Rare, low-frequency, and common variants in the protein-coding sequence of biological candidate genes from GWASs contribute to risk of rheumatoid arthritis D Diogo, F Kurreeman, EA Stahl, KP Liao, N Gupta, JD Greenberg, ... The American Journal of Human Genetics 92 (1), 15-27, 2013 | 113 | 2013 |
| Protein identification pipeline for the homology-driven proteomics M Junqueira, V Spirin, TS Balbuena, H Thomas, I Adzhubei, S Sunyaev, ... Journal of proteomics 71 (3), 346-356, 2008 | 90 | 2008 |
| Nonuniform size distribution of nascent globin peptides, evidence for pause localization sites, and a cotranslational protein-folding model IA Krasheninnikov, AA Komar, IA Adzhubei Journal of protein chemistry 10, 445-453, 1991 | 57 | 1991 |
| Hypermutable non-synonymous sites are under stronger negative selection S Schmidt, A Gerasimova, FA Kondrashov, IA Adzuhbei, AS Kondrashov, ... PLoS genetics 4 (11), e1000281, 2008 | 48 | 2008 |
| Separating the wheat from the chaff: unbiased filtering of background tandem mass spectra improves protein identification M Junqueira, V Spirin, T Santana Balbuena, P Waridel, V Surendranath, ... Journal of proteome research 7 (8), 3382-3395, 2008 | 48 | 2008 |
| An Integrated Sequence-Structure Database incorporating matching mRNA sequence, amino acid sequence and protein three-dimensional structure data IA Adzhubei, AA Adzhubei, S Neidle Nucleic acids research 26 (1), 327-331, 1998 | 42 | 1998 |
| Natural polypeptides in left‐handed helical conformation A circular dichroism study of the linker histones’ C‐terminal fragments and β‐endorphin AA Makarov, VM Lobachov, IA Adzhubei, NG Esipova FEBS letters 306 (1), 63-65, 1992 | 34 | 1992 |
| ISSD Version 2.0: taxonomic range extended IA Adzhubei, AA Adzhubei Nucleic acids research 27 (1), 268-271, 1999 | 30 | 1999 |
| Scanning microcalorimetry and circular dichroism study of melting of the natural polypeptides in the left-handed helical conformation AA Makarov, IA Adzhubei, II Protasevich, VM Lobachov, NG Esipova Journal of protein chemistry 12, 85-91, 1993 | 18 | 1993 |
| Melting of the left‐handed helical conformation of charged poly‐L‐lysine AA Makarov, IA Adzhubei, II Protasevich, VM Lobachov, GD Fasman Biopolymers: Original Research on Biomolecules 34 (8), 1123-1124, 1994 | 15 | 1994 |
Shamil SunyaevProfessor of Biomedical Informatics and of Medicine (BWH), Harvard Medical School在 rics.bwh.harvard.edu 的电子邮件经过验证
