Homozygous mutations in CSF1R cause a pediatric-onset leukoencephalopathy and can result in congenital absence of microglia N Oosterhof, IJ Chang, EG Karimiani, LE Kuil, DM Jensen, R Daza, ... The American Journal of Human Genetics 104 (5), 936-947, 2019 | 224 | 2019 |
Colony-stimulating factor 1 receptor (CSF1R) regulates microglia density and distribution, but not microglia differentiation in vivo N Oosterhof, LE Kuil, HC van der Linde, SM Burm, W Berdowski, ... Cell reports 24 (5), 1203-1217. e6, 2018 | 138 | 2018 |
Identification of a conserved and acute neurodegeneration‐specific microglial transcriptome in the zebrafish N Oosterhof, IR Holtman, LE Kuil, HC van der Linde, EWGM Boddeke, ... Glia 65 (1), 138-149, 2017 | 90 | 2017 |
Gene expression profiling reveals a conserved microglia signature in larval zebrafish J Mazzolini, S Le Clerc, G Morisse, C Coulonges, LE Kuil, TJ Van Ham, ... Glia 68 (2), 298-315, 2020 | 60 | 2020 |
Zebrafish: a model organism for studying enteric nervous system development and disease LE Kuil, RK Chauhan, WW Cheng, RMW Hofstra, MM Alves Frontiers in Cell and Developmental Biology 8, 629073, 2021 | 50 | 2021 |
Reverse genetic screen reveals that Il34 facilitates yolk sac macrophage distribution and seeding of the brain LE Kuil, N Oosterhof, SN Geurts, HC Van Der Linde, E Meijering, ... Disease models & mechanisms 12 (3), dmm037762, 2019 | 48 | 2019 |
Zebrafish macrophage developmental arrest underlies depletion of microglia and reveals Csf1r-independent metaphocytes LE Kuil, N Oosterhof, G Ferrero, T Mikulášová, M Hason, J Dekker, ... Elife 9, e53403, 2020 | 46 | 2020 |
Overexpression of mineralocorticoid receptors partially prevents chronic stress-induced reductions in hippocampal memory and structural plasticity S Kanatsou, BC Fearey, LE Kuil, PJ Lucassen, AP Harris, JR Seckl, ... PloS one 10 (11), e0142012, 2015 | 42 | 2015 |
Hexb enzyme deficiency leads to lysosomal abnormalities in radial glia and microglia in zebrafish brain development LE Kuil, A López Martí, A Carreras Mascaro, JC van den Bosch, ... Glia 67 (9), 1705-1718, 2019 | 36 | 2019 |
The health effect of probiotics on high-fat diet-induced cognitive impairment, depression and anxiety: A cross-species systematic review J Lof, K Smits, V Melotte, LE Kuil Neuroscience & Biobehavioral Reviews 136, 104634, 2022 | 28 | 2022 |
Size matters: large copy number losses in Hirschsprung disease patients reveal genes involved in enteric nervous system development LE Kuil, KC MacKenzie, CS Tang, JD Windster, TL Le, A Karim, ... PLoS Genetics 17 (8), e1009698, 2021 | 25 | 2021 |
Overexpression of mineralocorticoid receptors does not affect memory and anxiety-like behavior in female mice S Kanatsou, LE Kuil, M Arp, MS Oitzl, AP Harris, JR Seckl, HJ Krugers, ... Frontiers in behavioral neuroscience 9, 182, 2015 | 13 | 2015 |
Inhibition of ROCK signaling pathway accelerates enteric neural crest cell‐based therapy after transplantation in a rat hypoganglionic model Y Zhao, X Ge, H Yu, LE Kuil, MM Alves, D Tian, Q Huang, X Chen, ... Neurogastroenterology & Motility 32 (9), e13895, 2020 | 8 | 2020 |
TFAP2B Haploinsufficiency Impacts Gastrointestinal Function and Leads to Pediatric Intestinal Pseudo-obstruction A Zada, LE Kuil, BM de Graaf, N Kakiailatu, JD Windster, AS Brooks, ... Frontiers in cell and developmental biology 10, 901824, 2022 | 7 | 2022 |
Unbiased characterization of the larval zebrafish enteric nervous system at a single cell transcriptomic level LE Kuil, NJM Kakiailatu, JD Windster, E Bindels, JTM Zink, G van der Zee, ... Iscience 26 (7), 2023 | 6 | 2023 |
Microglial activation by genetically targeted conditional neuronal ablation in the zebrafish N Oosterhof, LE Kuil, TJ van Ham Inflammation: Methods and Protocols, 377-390, 2017 | 4 | 2017 |
ATP5PO levels regulate enteric nervous system development in zebrafish, linking Hirschsprung disease to Down Syndrome LE Kuil, RK Chauhan, BM de Graaf, WW Cheng, NJM Kakiailatu, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1870 (3), 166991, 2024 | 2 | 2024 |
Human enteric glia diversity in health and disease: new avenues for the treatment of Hirschsprung disease JD Windster, LE Kuil, NJM Kakiailatu, A Antanaviciute, A Sacchetti, ... bioRxiv, 2023.09. 26.559481, 2023 | 2 | 2023 |
Correction: overexpression of mineralocorticoid receptors partially prevents chronic stress-induced reductions in hippocampal memory and structural plasticity S Kanatsou, BC Fearey, LE Kuil, PJ Lucassen, AP Harris, JR Seckl, ... Plos one 10 (12), e0145706, 2015 | 2 | 2015 |
Fractionated brain X-irradiation profoundly reduces hippocampal immature neuron numbers without affecting spontaneous behavior in mice LE Kuil, R Seigers, M Loos, MC de Gooijer, A Compter, W Boogerd, ... Heliyon 10 (9), 2024 | 1 | 2024 |